iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062596

UUCD1 version

UUC-MoD-01017

Ensembl Protein ID

ENSMODP00000008625.2

UniProt Accession

F6QW29; F6QW29_MONDO

Protein Name

Uncharacterized protein

Gene Name

UBE2D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000006958.2	ENSMODT00000008795.2	ENSMODP00000008625.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.40e-55	187.0	5	138
UBD/UBC-like/UBD_UBC	5.90e-85	282.5	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  
   Q: 5    RINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR-- 90
           89**********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           ++Wspal++++vllsi+sll++pnp++pl  e+a+++k++r +y+++ 
   Q: 91   SQWSPALTLSKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRIS 138
           ********************************************9876 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqw
   Q: 5    RINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+altlskvlls+csll+d++pddplv+eiariyktd++ky+ri+rewt
   Q: 94   SPALTLSKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWT 142
           ************************************************8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTLS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTGA AACGGATTAA TAAGGAACTT AGCGATTTGG CCCGTGACCC TCCAGCACAG 60
TGTTCTGCAG GTCCAGTTGG GGATGATATG TTTCATTGGC AAGCCACAAT TATGGGACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004043	Anas platyrhynchos	93.88	1.00e-81	294.00
IUUC-Aor-010157	Aspergillus oryzae	84.35	4.00e-74	269.00
IUUC-Cpo-022334	Cavia porcellus	97.28	6.00e-83	298.00
IUUC-Dno-029156	Dasypus novemcinctus	97.90	4.00e-82	295.00
IUUC-Dor-030285	Dipodomys ordii	99.28	1.00e-80	291.00
IUUC-Eca-034286	Equus caballus	99.28	1.00e-80	291.00
IUUC-Fca-035917	Felis catus	99.32	2.00e-85	306.00
IUUC-Fal-036904	Ficedula albicollis	99.29	3.00e-81	293.00
IUUC-Fso-038297	Fusarium solani	82.99	2.00e-73	267.00
IUUC-Gmo-038898	Gadus morhua	97.20	7.00e-82	295.00
IUUC-Gga-041015	Gallus gallus	97.28	2.00e-84	303.00
IUUC-Gma-043733	Glycine max	80.27	1.00e-70	258.00
IUUC-Hsa-046157	Homo sapiens	99.32	2.00e-85	306.00
IUUC-Meu-056462	Macropus eugenii	97.84	2.00e-79	287.00
IUUC-Mga-059237	Meleagris gallopavo	99.29	4.00e-81	292.00
IUUC-Mmr-060889	Microcebus murinus	97.28	2.00e-84	303.00
IUUC-Mmu-063796	Mus musculus	97.28	2.00e-84	303.00
IUUC-Opr-070191	Ochotona princeps	99.28	1.00e-80	291.00
IUUC-Oga-088477	Otolemur garnettii	94.52	4.00e-82	296.00
IUUC-Oar-090038	Ovis aries	99.32	2.00e-85	306.00
IUUC-Ptr-091438	Pan troglodytes	97.96	2.00e-84	303.00
IUUC-Psi-094076	Pelodiscus sinensis	99.32	2.00e-85	306.00
IUUC-Pab-098293	Pongo abelii	97.99	6.00e-84	302.00
IUUC-Rno-105498	Rattus norvegicus	99.32	2.00e-85	306.00
IUUC-Sce-106463	Saccharomyces cerevisiae	81.25	4.00e-70	256.00
IUUC-Spo-108032	Schizosaccharomyces pombe	83.67	2.00e-73	267.00
IUUC-Ssc-116154	Sus scrofa	95.24	2.00e-82	296.00
IUUC-Tgu-116727	Taeniopygia guttata	99.32	2.00e-85	306.00
IUUC-Tme-126912	Tuber melanosporum	81.63	7.00e-72	262.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence