iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059237

UUCD1 version

UUC-MeG-00765

Ensembl Protein ID

ENSMGAP00000011867.1

UniProt Accession

G1NFR2; G1NFR2_MELGA

Protein Name

Uncharacterized protein

Gene Name

UBE2D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000011349.1	ENSMGAT00000012749.1	ENSMGAP00000011867.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.30e-55	184.3	7	138
UBD/UBC-like/UBD_UBC	1.10e-83	278.0	8	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 3    kkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
            kel++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++
   Q: 7    PKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQ 92
           59********************.9************************************************************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           Wspal++++vllsi+sll++pnp++pl  e+a+++k++r +y+++ 
   Q: 93   WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRIS 138
           ******************************************9876 PP

UBD/UBC-like/UBD_UBC

   S: 4    kelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaa 92
           kel+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+a
   Q: 8    KELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPA 96
           9**************************************************************************************** PP
   S: 93   ltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           lt+skvlls+csll+d++pddplv+eiariyktd++ky+ri+rewt
   Q: 97   LTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWT 142
           *********************************************8 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

VFFLFLPKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTTTTTT TGTTTCTTCC TAAGGAACTT AGTGACTTAG CTCGTGATCC TCCAGCGCAG 60
TGTTCAGCAG GTCCTGTTGG AGATGACAGT AAGTAATCTT AGGTTTTTAG TTTTCTCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	79.29	1.00e-66	244.00
IUUC-Aml-001778	Ailuropoda melanoleuca	97.86	4.00e-80	289.00
IUUC-Atr-002861	Amborella trichopoda	80.71	1.00e-67	248.00
IUUC-Apl-004043	Anas platyrhynchos	94.48	6.00e-81	291.00
IUUC-Aca-005236	Anolis carolinensis	97.86	2.00e-80	290.00
IUUC-Aly-006221	Arabidopsis lyrata	80.71	2.00e-67	247.00
IUUC-Ath-007495	Arabidopsis thaliana	80.00	5.00e-67	246.00
IUUC-Ago-007967	Ashbya gossypii	78.87	2.00e-67	247.00
IUUC-Acl-008266	Aspergillus clavatus	84.29	4.00e-70	256.00
IUUC-Afl-008709	Aspergillus flavus	76.87	7.00e-69	254.00
IUUC-Afu-008956	Aspergillus fumigatus	85.00	2.00e-70	256.00
IUUC-Ani-009401	Aspergillus nidulans	82.86	4.00e-69	252.00
IUUC-Ang-009725	Aspergillus niger	84.00	1.00e-61	227.00
IUUC-Aor-010157	Aspergillus oryzae	84.29	3.00e-70	256.00
IUUC-Ate-010438	Aspergillus terreus	83.57	2.00e-69	253.00
IUUC-Ame-011831	Astyanax mexicanus	94.37	4.00e-79	285.00
IUUC-Bgr-012238	Blumeria graminis	79.29	5.00e-66	242.00
IUUC-Bta-013158	Bos taurus	97.86	2.00e-80	290.00
IUUC-Bci-013661	Botrytis cinerea	82.86	3.00e-70	256.00
IUUC-Bdi-014561	Brachypodium distachyon	80.00	2.00e-67	247.00
IUUC-Bol-015722	Brassica oleracea	81.43	2.00e-67	247.00
IUUC-Bra-016748	Brassica rapa	79.29	1.00e-67	250.00
IUUC-Cel-018362	Caenorhabditis elegans	92.86	4.00e-77	279.00
IUUC-Cja-019886	Callithrix jacchus	97.86	2.00e-80	290.00
IUUC-Cfa-020436	Canis familiaris	97.86	2.00e-80	290.00
IUUC-Cpo-022334	Cavia porcellus	97.86	5.00e-79	285.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	78.57	8.00e-66	241.00
IUUC-Csa-023377	Chlorocebus sabaeus	90.71	2.00e-76	276.00
IUUC-Cin-025379	Ciona intestinalis	85.61	1.00e-72	263.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	83.57	6.00e-70	255.00
IUUC-Cne-026957	Cryptococcus neoformans	79.14	2.00e-65	239.00
IUUC-Dre-027758	Danio rerio	97.14	8.00e-80	288.00
IUUC-Dno-028952	Dasypus novemcinctus	95.21	2.00e-81	293.00
IUUC-Dor-030285	Dipodomys ordii	100.00	1.00e-80	290.00
IUUC-Dse-031397	Dothistroma septosporum	83.57	4.00e-70	256.00
IUUC-Dme-031594	Drosophila melanogaster	93.57	5.00e-77	278.00
IUUC-Ete-032295	Echinops telfairi	97.84	1.00e-79	287.00
IUUC-Eca-034286	Equus caballus	100.00	1.00e-80	290.00
IUUC-Eeu-034766	Erinaceus europaeus	97.14	2.00e-78	283.00
IUUC-Fca-035917	Felis catus	100.00	2.00e-81	293.00
IUUC-Fal-036904	Ficedula albicollis	100.00	3.00e-81	292.00
IUUC-Fox-038021	Fusarium oxysporum	83.57	1.00e-69	254.00
IUUC-Fso-038297	Fusarium solani	82.86	2.00e-69	253.00
IUUC-Gmo-038898	Gadus morhua	97.79	5.00e-78	281.00
IUUC-Ggr-039912	Gaeumannomyces graminis	78.62	2.00e-65	240.00
IUUC-Gga-041015	Gallus gallus	97.86	1.00e-80	291.00
IUUC-Gac-042231	Gasterosteus aculeatus	95.00	3.00e-78	283.00
IUUC-Gma-043733	Glycine max	80.71	4.00e-68	249.00
IUUC-Ggo-045076	Gorilla gorilla	97.89	2.00e-80	290.00
IUUC-Hsa-046157	Homo sapiens	100.00	2.00e-81	293.00
IUUC-Hvu-047546	Hordeum vulgare	77.86	5.00e-66	242.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	96.50	1.00e-80	291.00
IUUC-Kpa-049290	Komagataella pastoris	78.57	6.00e-66	241.00
IUUC-Lpe-050972	Leersia perrieri	80.00	2.00e-67	246.00
IUUC-Loc-052788	Lepisosteus oculatus	95.71	4.00e-79	285.00
IUUC-Lma-053121	Leptosphaeria maculans	83.57	2.00e-70	256.00
IUUC-Laf-053580	Loxodonta africana	97.86	3.00e-80	289.00
IUUC-Mcc-054672	Macaca mulatta	97.84	4.00e-80	289.00
IUUC-Meu-056462	Macropus eugenii	98.56	2.00e-79	286.00
IUUC-Mor-057235	Magnaporthe oryzae	82.86	4.00e-69	252.00
IUUC-Mpo-057596	Magnaporthe poae	78.62	5.00e-65	239.00
IUUC-Mtr-058532	Medicago truncatula	80.00	6.00e-67	245.00
IUUC-Mla-059189	Melampsora laricipopulina	80.00	9.00e-65	238.00
IUUC-Mvi-060397	Microbotryum violaceum	81.43	7.00e-68	248.00
IUUC-Mmr-061550	Microcebus murinus	100.00	9.00e-81	291.00
IUUC-Mdo-062596	Monodelphis domestica	99.29	3.00e-81	292.00
IUUC-Mmu-063796	Mus musculus	97.86	1.00e-80	291.00
IUUC-Mac-064668	Musa acuminata	80.71	5.00e-67	246.00
IUUC-Mpu-066604	Mustela putorius furo	96.48	3.00e-80	290.00
IUUC-Nfi-068599	Neosartorya fischeri	85.00	2.00e-70	256.00
IUUC-Ncr-068677	Neurospora crassa	82.14	2.00e-68	250.00
IUUC-Nle-069800	Nomascus leucogenys	95.10	7.00e-78	281.00
IUUC-Opr-070191	Ochotona princeps	100.00	1.00e-80	290.00
IUUC-Ont-071766	Oreochromis niloticus	96.43	1.00e-79	287.00
IUUC-Oan-073026	Ornithorhynchus anatinus	91.43	1.00e-76	278.00
IUUC-Ocu-074315	Oryctolagus cuniculus	97.86	2.00e-80	290.00
IUUC-Oba-075411	Oryza barthii	80.00	2.00e-67	246.00
IUUC-Obr-076658	Oryza brachyantha	80.00	2.00e-67	246.00
IUUC-Ogl-076968	Oryza glaberrima	80.71	1.00e-67	247.00
IUUC-Ogu-078981	Oryza glumaepatula	80.00	2.00e-67	246.00
IUUC-Oin-079659	Oryza indica	80.71	1.00e-67	247.00
IUUC-Olo-080786	Oryza longistaminata	80.00	2.00e-67	246.00
IUUC-Ome-081987	Oryza meridionalis	79.29	8.00e-67	244.00
IUUC-Oni-082391	Oryza nivara	79.58	8.00e-68	249.00
IUUC-Opu-083833	Oryza punctata	80.00	2.00e-67	246.00
IUUC-Oru-085167	Oryza rufipogon	79.58	9.00e-68	249.00
IUUC-Osa-086003	Oryza sativa	80.71	1.00e-67	247.00
IUUC-Ola-086331	Oryzias latipes	96.43	1.00e-79	287.00
IUUC-Olu-087615	Ostreococcus lucimarinus	76.43	6.00e-63	232.00
IUUC-Oga-088477	Otolemur garnettii	95.77	2.00e-80	290.00
IUUC-Oar-090038	Ovis aries	100.00	2.00e-81	293.00
IUUC-Ptr-091438	Pan troglodytes	98.57	2.00e-80	290.00
IUUC-Pan-092143	Papio anubis	97.86	2.00e-80	290.00
IUUC-Psi-094076	Pelodiscus sinensis	100.00	2.00e-81	293.00
IUUC-Pma-094405	Petromyzon marinus	94.07	7.00e-74	268.00
IUUC-Pno-094765	Phaeosphaeria nodorum	83.57	2.00e-70	256.00
IUUC-Ppa-095177	Physcomitrella patens	80.71	3.00e-67	246.00
IUUC-Pfo-096753	Poecilia formosa	96.43	1.00e-79	287.00
IUUC-Pab-097764	Pongo abelii	97.86	2.00e-80	290.00
IUUC-Pop-098878	Populus trichocarpa	80.71	3.00e-67	247.00
IUUC-Ppe-101431	Prunus persica	81.43	2.00e-67	247.00
IUUC-Pgr-103381	Puccinia graminis	81.43	1.00e-65	241.00
IUUC-Ptt-103723	Puccinia triticina	77.30	2.00e-61	227.00
IUUC-Pte-104015	Pyrenophora teres	83.57	3.00e-70	256.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	83.57	3.00e-70	256.00
IUUC-Rno-105498	Rattus norvegicus	100.00	2.00e-81	293.00
IUUC-Sce-106463	Saccharomyces cerevisiae	79.58	4.00e-68	249.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	83.57	5.00e-69	252.00
IUUC-Spo-108032	Schizosaccharomyces pombe	83.57	2.00e-69	253.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	83.57	2.00e-70	257.00
IUUC-Smo-109317	Selaginella moellendorffii	80.71	6.00e-67	245.00
IUUC-Sit-109936	Setaria italica	79.29	1.00e-67	248.00
IUUC-Sly-111614	Solanum lycopersicum	80.71	8.00e-68	248.00
IUUC-Stu-112629	Solanum tuberosum	80.71	8.00e-68	248.00
IUUC-Sar-113302	Sorex araneus	97.84	1.00e-79	287.00
IUUC-Sbi-114840	Sorghum bicolor	80.71	1.00e-67	247.00
IUUC-Sre-115037	Sporisorium reilianum	80.29	7.00e-66	241.00
IUUC-Ssc-116154	Sus scrofa	95.92	2.00e-81	293.00
IUUC-Tgu-116727	Taeniopygia guttata	100.00	2.00e-81	293.00
IUUC-Tru-118272	Takifugu rubripes	96.43	5.00e-79	285.00
IUUC-Tsy-119491	Tarsius syrichta	94.96	5.00e-75	273.00
IUUC-Tni-120056	Tetraodon nigroviridis	96.43	5.00e-79	285.00
IUUC-Tca-121542	Theobroma cacao	78.17	1.00e-67	248.00
IUUC-Tre-122125	Trichoderma reesei	81.43	2.00e-67	246.00
IUUC-Tvi-122296	Trichoderma virens	81.43	2.00e-67	246.00
IUUC-Tae-123340	Triticum aestivum	81.43	2.00e-68	250.00
IUUC-Tur-126518	Triticum urartu	79.29	5.00e-67	246.00
IUUC-Tme-126912	Tuber melanosporum	81.43	5.00e-68	248.00
IUUC-Tbe-127609	Tupaia belangeri	98.29	1.00e-66	244.00
IUUC-Uma-129648	Ustilago maydis	81.43	6.00e-68	248.00
IUUC-Vda-129695	Verticillium dahliae	83.57	6.00e-70	255.00
IUUC-Vpa-130446	Vicugna pacos	97.14	6.00e-79	286.00
IUUC-Vvi-131700	Vitis vinifera	80.71	3.00e-67	246.00
IUUC-Xtr-132329	Xenopus tropicalis	97.86	2.00e-80	290.00
IUUC-Xma-133829	Xiphophorus maculatus	96.43	1.00e-79	287.00
IUUC-Yli-134353	Yarrowia lipolytica	78.57	3.00e-67	246.00
IUUC-Zma-135956	Zea mays	79.29	8.00e-67	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence