iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067573

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02037601

Gene Name

UBE2D1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000005710.2	ENSMLUT00000005712.2	ENSMLUP00000005220.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	8.20e-55	184.4	1	132
UBD/UBC-like/UBD_UBC	4.10e-82	273.2	1	135

Active Site

Position(s)	Description	Evidence
78	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           +el++l++dpp+++sa+pv + dl++w+++i+Gp+d+ Y+ggvF l+++fp+dYPfkPPk+ f+tki+hPn+++nG++Cl+il+  ++W
   Q: 1    QELSDLQRDPPAHCSAGPVGD-DLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILR--SQW 86
           699******************.9************************************************************9..*** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           spal+v++vllsi+sll++pnp++pl  ++a+++k+++e+y++++r
   Q: 87   SPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAR 132
           *******************************************987 PP

UBD/UBC-like/UBD_UBC

   S: 4    kelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaa 92
           +el+dl+rd++a++sa++v+ddlf+++ati+gppds+y+ggvfflt+++ptdypfkppk+af+tkiyhpninsngsicldilrsqws+a
   Q: 1    QELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPA 89
           69*************************************************************************************** PP
   S: 93   ltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           lt+skvlls+csll+d++pddplv++ia+iyk+dkeky+r+arewt
   Q: 90   LTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWT 135
           *********************************************8 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

QELSDLQRDP PAHCSAGPVG DDLFHWQATI MGPPDSAYQG GVFFLTVHFP TDYPFKPPKI 60
AFTTKIYHPN INSNGSICLD ILRSQWSPAL TVSKVLLSIC SLLCDPNPDD PLVPDIAQIY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAATTAA GTGATCTACA GCGTGACCCA CCTGCTCACT GCTCCGCCGG ACCTGTGGGA 60
GACGACCGTA AGCTTTGCTT TATTGCTAGC ATTTTGCTAC AGTTAATAAT ACAGGTTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	75.71	3.00e-65	240.00
IUUC-Aml-001563	Ailuropoda melanoleuca	99.29	4.00e-81	292.00
IUUC-Atr-002614	Amborella trichopoda	77.14	7.00e-66	242.00
IUUC-Apl-003639	Anas platyrhynchos	100.00	2.00e-81	293.00
IUUC-Aca-005254	Anolis carolinensis	99.29	4.00e-81	292.00
IUUC-Aly-006542	Arabidopsis lyrata	75.71	1.00e-65	241.00
IUUC-Ath-007224	Arabidopsis thaliana	75.71	1.00e-65	241.00
IUUC-Ago-007967	Ashbya gossypii	78.57	3.00e-66	243.00
IUUC-Acl-008266	Aspergillus clavatus	79.29	5.00e-67	246.00
IUUC-Afl-008709	Aspergillus flavus	75.71	1.00e-65	244.00
IUUC-Afu-008956	Aspergillus fumigatus	80.00	2.00e-67	247.00
IUUC-Ani-009401	Aspergillus nidulans	77.86	5.00e-66	242.00
IUUC-Ang-009725	Aspergillus niger	79.20	4.00e-59	219.00
IUUC-Aor-010157	Aspergillus oryzae	79.29	7.00e-67	245.00
IUUC-Ate-010438	Aspergillus terreus	78.57	3.00e-66	243.00
IUUC-Ame-011566	Astyanax mexicanus	93.57	2.00e-76	276.00
IUUC-Bgr-012238	Blumeria graminis	74.29	5.00e-63	232.00
IUUC-Bta-013467	Bos taurus	99.29	4.00e-81	292.00
IUUC-Bci-013661	Botrytis cinerea	77.86	5.00e-67	246.00
IUUC-Bdi-014712	Brachypodium distachyon	78.57	8.00e-66	241.00
IUUC-Bol-016390	Brassica oleracea	76.43	8.00e-66	242.00
IUUC-Bra-016748	Brassica rapa	76.43	1.00e-65	244.00
IUUC-Cel-018362	Caenorhabditis elegans	87.86	5.00e-74	269.00
IUUC-Cja-019302	Callithrix jacchus	99.29	4.00e-81	292.00
IUUC-Cfa-021087	Canis familiaris	99.29	4.00e-81	292.00
IUUC-Cpo-021897	Cavia porcellus	90.65	5.00e-74	269.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	75.71	4.00e-64	236.00
IUUC-Csa-023668	Chlorocebus sabaeus	99.29	4.00e-81	292.00
IUUC-Cho-024987	Choloepus hoffmanni	99.29	4.00e-81	292.00
IUUC-Cin-025379	Ciona intestinalis	84.17	2.00e-70	257.00
IUUC-Csv-026311	Ciona savignyi	83.45	5.00e-69	252.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	78.57	1.00e-66	244.00
IUUC-Cne-026957	Cryptococcus neoformans	76.26	2.00e-63	234.00
IUUC-Cme-027220	Cyanidioschyzon merolae	80.71	1.00e-67	248.00
IUUC-Dre-028568	Danio rerio	93.57	2.00e-76	276.00
IUUC-Dno-030067	Dasypus novemcinctus	99.29	4.00e-81	292.00
IUUC-Dor-030474	Dipodomys ordii	99.29	4.00e-81	292.00
IUUC-Dse-031397	Dothistroma septosporum	78.57	5.00e-67	246.00
IUUC-Dme-031594	Drosophila melanogaster	88.57	4.00e-74	269.00
IUUC-Ete-032540	Echinops telfairi	99.29	4.00e-81	292.00
IUUC-Eca-034167	Equus caballus	99.29	4.00e-81	292.00
IUUC-Eeu-034766	Erinaceus europaeus	87.86	3.00e-72	263.00
IUUC-Fca-035917	Felis catus	87.86	8.00e-74	268.00
IUUC-Fal-036904	Ficedula albicollis	87.86	1.00e-73	267.00
IUUC-Fox-038021	Fusarium oxysporum	78.57	1.00e-66	244.00
IUUC-Fso-038297	Fusarium solani	77.86	3.00e-66	243.00
IUUC-Gmo-038775	Gadus morhua	90.71	5.00e-74	269.00
IUUC-Ggr-039912	Gaeumannomyces graminis	73.10	1.00e-61	228.00
IUUC-Gga-040873	Gallus gallus	99.29	4.00e-81	292.00
IUUC-Gac-042534	Gasterosteus aculeatus	89.93	4.00e-73	266.00
IUUC-Gma-043733	Glycine max	78.57	3.00e-66	243.00
IUUC-Ggo-045361	Gorilla gorilla	90.71	5.00e-75	272.00
IUUC-Hsa-045951	Homo sapiens	99.29	4.00e-81	292.00
IUUC-Hvu-047546	Hordeum vulgare	73.57	1.00e-63	234.00
IUUC-Itr-048743	Ictidomys tridecemlineatus	99.29	4.00e-81	292.00
IUUC-Kpa-049290	Komagataella pastoris	78.57	3.00e-65	240.00
IUUC-Lch-050109	Latimeria chalumnae	87.86	5.00e-73	265.00
IUUC-Lpe-051289	Leersia perrieri	77.14	1.00e-65	241.00
IUUC-Loc-051773	Lepisosteus oculatus	93.57	4.00e-76	276.00
IUUC-Lma-053121	Leptosphaeria maculans	78.57	3.00e-67	246.00
IUUC-Laf-053673	Loxodonta africana	100.00	2.00e-81	293.00
IUUC-Mcc-055719	Macaca mulatta	99.29	4.00e-81	292.00
IUUC-Meu-056462	Macropus eugenii	87.05	3.00e-72	263.00
IUUC-Mor-057235	Magnaporthe oryzae	77.86	5.00e-66	242.00
IUUC-Mpo-057596	Magnaporthe poae	73.10	2.00e-61	227.00
IUUC-Mtr-057667	Medicago truncatula	77.14	8.00e-65	238.00
IUUC-Mla-059189	Melampsora laricipopulina	75.00	7.00e-62	228.00
IUUC-Mga-060138	Meleagris gallopavo	100.00	2.00e-81	293.00
IUUC-Mvi-060397	Microbotryum violaceum	79.29	4.00e-66	243.00
IUUC-Mmr-061212	Microcebus murinus	99.29	4.00e-81	292.00
IUUC-Mdo-062402	Monodelphis domestica	99.29	7.00e-81	292.00
IUUC-Mmu-063779	Mus musculus	99.29	4.00e-81	292.00
IUUC-Mac-064668	Musa acuminata	77.14	3.00e-66	244.00
IUUC-Mpu-065724	Mustela putorius furo	99.29	4.00e-81	292.00
IUUC-Nfi-068599	Neosartorya fischeri	80.00	2.00e-67	247.00
IUUC-Ncr-068677	Neurospora crassa	77.14	1.00e-65	241.00
IUUC-Nle-069950	Nomascus leucogenys	99.29	4.00e-81	292.00
IUUC-Opr-070191	Ochotona princeps	88.49	2.00e-73	267.00
IUUC-Ont-072562	Oreochromis niloticus	89.29	5.00e-74	269.00
IUUC-Oan-073149	Ornithorhynchus anatinus	100.00	6.00e-81	292.00
IUUC-Ocu-074315	Oryctolagus cuniculus	88.57	3.00e-74	270.00
IUUC-Oba-075411	Oryza barthii	77.14	3.00e-65	240.00
IUUC-Obr-076658	Oryza brachyantha	75.71	6.00e-65	239.00
IUUC-Ogl-077772	Oryza glaberrima	77.14	3.00e-65	240.00
IUUC-Ogu-078981	Oryza glumaepatula	77.14	3.00e-65	240.00
IUUC-Oin-079652	Oryza indica	77.14	3.00e-65	240.00
IUUC-Olo-080786	Oryza longistaminata	77.14	3.00e-65	240.00
IUUC-Ome-081967	Oryza meridionalis	75.71	7.00e-65	238.00
IUUC-Oni-082391	Oryza nivara	76.43	2.00e-65	242.00
IUUC-Opu-083481	Oryza punctata	76.43	5.00e-65	239.00
IUUC-Oru-085167	Oryza rufipogon	76.43	2.00e-65	242.00
IUUC-Osa-086003	Oryza sativa	76.43	5.00e-65	239.00
IUUC-Ola-087515	Oryzias latipes	90.00	2.00e-74	270.00
IUUC-Olu-087615	Ostreococcus lucimarinus	72.86	3.00e-60	223.00
IUUC-Oga-088915	Otolemur garnettii	99.29	4.00e-81	292.00
IUUC-Oar-090418	Ovis aries	99.29	5.00e-81	292.00
IUUC-Ptr-091575	Pan troglodytes	99.29	4.00e-81	292.00
IUUC-Pan-092922	Papio anubis	99.29	4.00e-81	292.00
IUUC-Psi-094076	Pelodiscus sinensis	87.86	8.00e-74	268.00
IUUC-Pma-094405	Petromyzon marinus	87.97	8.00e-69	251.00
IUUC-Pno-094765	Phaeosphaeria nodorum	78.57	3.00e-67	246.00
IUUC-Ppa-095177	Physcomitrella patens	77.14	5.00e-66	243.00
IUUC-Pfo-096867	Poecilia formosa	90.00	2.00e-74	270.00
IUUC-Pab-098137	Pongo abelii	99.29	4.00e-81	292.00
IUUC-Pop-100017	Populus trichocarpa	77.14	7.00e-66	242.00
IUUC-Pca-100678	Procavia capensis	99.29	4.00e-81	292.00
IUUC-Ppe-101387	Prunus persica	77.14	7.00e-66	242.00
IUUC-Pva-102770	Pteropus vampyrus	99.29	4.00e-81	292.00
IUUC-Pgr-103381	Puccinia graminis	76.43	2.00e-62	231.00
IUUC-Ptt-103723	Puccinia triticina	74.29	8.00e-59	219.00
IUUC-Pte-104015	Pyrenophora teres	78.57	5.00e-67	246.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	78.57	5.00e-67	246.00
IUUC-Rno-106124	Rattus norvegicus	99.29	4.00e-81	292.00
IUUC-Sce-106153	Saccharomyces cerevisiae	80.00	2.00e-66	244.00
IUUC-Sha-106489	Sarcophilus harrisii	100.00	1.00e-81	294.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	79.29	9.00e-67	244.00
IUUC-Spo-108032	Schizosaccharomyces pombe	79.29	4.00e-67	246.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	78.57	2.00e-67	247.00
IUUC-Smo-108911	Selaginella moellendorffii	77.14	1.00e-65	241.00
IUUC-Sit-109936	Setaria italica	77.14	2.00e-65	242.00
IUUC-Sly-111097	Solanum lycopersicum	77.86	3.00e-66	243.00
IUUC-Stu-112192	Solanum tuberosum	77.86	3.00e-66	243.00
IUUC-Sar-113557	Sorex araneus	100.00	1.00e-80	291.00
IUUC-Sbi-114840	Sorghum bicolor	76.43	3.00e-65	239.00
IUUC-Sre-115037	Sporisorium reilianum	75.18	3.00e-63	233.00
IUUC-Ssc-115391	Sus scrofa	90.71	5.00e-75	272.00
IUUC-Tgu-117399	Taeniopygia guttata	99.29	6.00e-81	292.00
IUUC-Tru-118272	Takifugu rubripes	87.14	9.00e-73	265.00
IUUC-Tsy-118832	Tarsius syrichta	88.57	2.00e-72	263.00
IUUC-Tni-120056	Tetraodon nigroviridis	87.14	9.00e-73	265.00
IUUC-Tca-121110	Theobroma cacao	77.14	7.00e-66	242.00
IUUC-Tre-122125	Trichoderma reesei	76.43	3.00e-64	236.00
IUUC-Tvi-122296	Trichoderma virens	76.43	3.00e-64	236.00
IUUC-Tae-123340	Triticum aestivum	77.14	5.00e-66	242.00
IUUC-Tur-126518	Triticum urartu	75.71	1.00e-65	242.00
IUUC-Tme-126912	Tuber melanosporum	76.43	2.00e-65	240.00
IUUC-Tbe-128122	Tupaia belangeri	88.71	1.00e-55	207.00
IUUC-Ttr-128363	Tursiops truncatus	99.29	4.00e-81	292.00
IUUC-Uma-129648	Ustilago maydis	76.43	2.00e-65	240.00
IUUC-Vda-129695	Verticillium dahliae	78.57	1.00e-66	244.00
IUUC-Vpa-130352	Vicugna pacos	92.81	2.00e-67	247.00
IUUC-Vvi-131700	Vitis vinifera	77.14	7.00e-66	242.00
IUUC-Xtr-132284	Xenopus tropicalis	94.29	3.00e-77	279.00
IUUC-Xma-133829	Xiphophorus maculatus	87.14	4.00e-73	266.00
IUUC-Yli-134353	Yarrowia lipolytica	75.71	3.00e-65	239.00
IUUC-Zma-135569	Zea mays	75.71	6.00e-65	239.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence