iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073026

UUCD1 version

UUC-OrA-00757

Ensembl Protein ID

ENSOANP00000000943.2

UniProt Accession

F7F3X2; F7F3X2_ORNAN

Protein Name

Uncharacterized protein

Gene Name

UBE2D4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000000598.2	ENSOANT00000000944.2	ENSOANP00000000943.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.20e-55	186.4	43	174
UBD/UBC-like/UBD_UBC	1.80e-81	271.3	42	177

Active Site

Position(s)	Description	Evidence
120	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           +el++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  ++W
   Q: 43   QELTDLQRDPPAQCSAGPVGD-DLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR--SQW 128
           89*******************.9************************************************************9..*** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           spal+v++vllsi+sll++pnp++pl  e+a+++k++re+y++ +r
   Q: 129  SPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAR 174
           ******************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 3    kkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsa 91
            +el dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqws+
   Q: 42   SQELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSP 130
           589************************************************************************************** PP
   S: 92   altlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           alt+skvlls+csll+d++pddplv+eia+ yk+d+eky+r arewt
   Q: 131  ALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAREWT 177
           **********************************************8 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

METAVRTLWK ISWMGGGASQ RLRRLAAGGL GPPGPELPFS CSQELTDLQR DPPAQCSAGP 60
VGDDLFHWQA TIMGPNDSPY QGGVFFLTIH FPTDYPFKPP KVAFTTKIYH PNINSNGSIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCAGGGTA GCTCGAAAGA GGGTCTCGCC CTCGGAACGG GCTGCGTCTG GCCTTCTCTG 60
GAAAGGACTC CTTCGGATGG CTCCCGCCCA GCTCCGTGGC CGTGACAAGG ACCTCTTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000292	Aegilops tauschii	79.29	3.00e-67	246.00
IUUC-Aml-001778	Ailuropoda melanoleuca	92.86	2.00e-77	279.00
IUUC-Atr-002782	Amborella trichopoda	80.71	6.00e-68	248.00
IUUC-Apl-004043	Anas platyrhynchos	91.49	1.00e-77	280.00
IUUC-Aca-005236	Anolis carolinensis	92.86	1.00e-77	280.00
IUUC-Aly-006221	Arabidopsis lyrata	80.85	1.00e-68	251.00
IUUC-Ath-007700	Arabidopsis thaliana	80.85	1.00e-67	247.00
IUUC-Ago-007967	Ashbya gossypii	79.43	8.00e-68	248.00
IUUC-Acl-008266	Aspergillus clavatus	83.69	2.00e-70	256.00
IUUC-Afl-008709	Aspergillus flavus	80.71	7.00e-69	254.00
IUUC-Afu-008956	Aspergillus fumigatus	84.40	9.00e-71	258.00
IUUC-Ani-009401	Aspergillus nidulans	82.27	2.00e-69	253.00
IUUC-Ang-009725	Aspergillus niger	84.00	6.00e-62	228.00
IUUC-Aor-010157	Aspergillus oryzae	82.27	2.00e-69	253.00
IUUC-Ate-010438	Aspergillus terreus	82.98	1.00e-69	254.00
IUUC-Ame-011566	Astyanax mexicanus	95.00	6.00e-79	285.00
IUUC-Bgr-012238	Blumeria graminis	77.86	1.00e-65	241.00
IUUC-Bta-013158	Bos taurus	92.86	1.00e-77	280.00
IUUC-Bci-013661	Botrytis cinerea	82.27	2.00e-70	256.00
IUUC-Bdi-014712	Brachypodium distachyon	82.14	1.00e-68	250.00
IUUC-Bol-015722	Brassica oleracea	81.56	2.00e-69	253.00
IUUC-Bra-016748	Brassica rapa	79.29	3.00e-68	252.00
IUUC-Cel-018362	Caenorhabditis elegans	91.43	1.00e-75	273.00
IUUC-Cja-019014	Callithrix jacchus	98.57	1.00e-81	294.00
IUUC-Cfa-020436	Canis familiaris	92.86	1.00e-77	280.00
IUUC-Cpo-021897	Cavia porcellus	99.28	6.00e-81	291.00
IUUC-Cre-022765	Chlamydomonas reinhardtii	79.29	5.00e-67	245.00
IUUC-Csa-023377	Chlorocebus sabaeus	97.87	3.00e-81	293.00
IUUC-Cin-025379	Ciona intestinalis	87.14	1.00e-72	264.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	82.98	5.00e-70	255.00
IUUC-Cne-026957	Cryptococcus neoformans	79.29	2.00e-66	243.00
IUUC-Cme-027220	Cyanidioschyzon merolae	82.98	3.00e-69	252.00
IUUC-Dre-028686	Danio rerio	98.57	2.00e-81	293.00
IUUC-Dno-028952	Dasypus novemcinctus	90.97	1.00e-77	280.00
IUUC-Dor-030323	Dipodomys ordii	98.57	2.00e-81	293.00
IUUC-Dse-031397	Dothistroma septosporum	82.98	2.00e-70	256.00
IUUC-Dme-031594	Drosophila melanogaster	91.49	9.00e-76	274.00
IUUC-Ete-032295	Echinops telfairi	93.53	2.00e-77	279.00
IUUC-Eca-033231	Equus caballus	100.00	2.00e-81	293.00
IUUC-Eeu-034766	Erinaceus europaeus	92.14	1.00e-75	273.00
IUUC-Fca-035917	Felis catus	90.78	3.00e-77	279.00
IUUC-Fal-036904	Ficedula albicollis	91.43	7.00e-77	278.00
IUUC-Fox-038021	Fusarium oxysporum	82.98	5.00e-70	255.00
IUUC-Fso-038297	Fusarium solani	82.27	1.00e-69	254.00
IUUC-Gmo-038775	Gadus morhua	90.71	3.00e-76	276.00
IUUC-Ggr-039912	Gaeumannomyces graminis	77.40	2.00e-65	239.00
IUUC-Gga-040758	Gallus gallus	92.86	1.00e-77	280.00
IUUC-Gac-042534	Gasterosteus aculeatus	92.81	3.00e-76	276.00
IUUC-Gma-043733	Glycine max	80.85	8.00e-69	251.00
IUUC-Ggo-045361	Gorilla gorilla	99.29	8.00e-82	294.00
IUUC-Hsa-045934	Homo sapiens	99.29	8.00e-82	294.00
IUUC-Hvu-047546	Hordeum vulgare	77.86	9.00e-67	244.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	92.91	3.00e-78	282.00
IUUC-Kpa-049290	Komagataella pastoris	78.72	6.00e-67	245.00
IUUC-Lch-050109	Latimeria chalumnae	86.52	5.00e-74	268.00
IUUC-Lpe-051289	Leersia perrieri	81.43	2.00e-68	250.00
IUUC-Loc-052838	Lepisosteus oculatus	99.29	8.00e-82	294.00
IUUC-Lma-053121	Leptosphaeria maculans	82.98	1.00e-70	257.00
IUUC-Laf-053580	Loxodonta africana	92.86	2.00e-77	280.00
IUUC-Mcc-055421	Macaca mulatta	99.29	8.00e-82	294.00
IUUC-Meu-056462	Macropus eugenii	90.65	1.00e-75	273.00
IUUC-Mor-057235	Magnaporthe oryzae	82.27	2.00e-69	253.00
IUUC-Mpo-057596	Magnaporthe poae	77.40	5.00e-65	238.00
IUUC-Mtr-058257	Medicago truncatula	80.00	1.00e-67	247.00
IUUC-Mla-059189	Melampsora laricipopulina	78.01	5.00e-64	235.00
IUUC-Mga-059237	Meleagris gallopavo	91.43	9.00e-77	277.00
IUUC-Mvi-060397	Microbotryum violaceum	80.14	9.00e-68	248.00
IUUC-Mmr-061446	Microcebus murinus	97.12	1.00e-79	287.00
IUUC-Mdo-062413	Monodelphis domestica	99.28	7.00e-81	291.00
IUUC-Mmu-063518	Mus musculus	92.86	1.00e-77	280.00
IUUC-Mac-064668	Musa acuminata	80.71	5.00e-68	249.00
IUUC-Mpu-066604	Mustela putorius furo	92.91	3.00e-78	282.00
IUUC-Nfi-068599	Neosartorya fischeri	84.40	9.00e-71	258.00
IUUC-Ncr-068677	Neurospora crassa	80.85	3.00e-68	249.00
IUUC-Nle-069715	Nomascus leucogenys	99.29	8.00e-82	294.00
IUUC-Opr-070191	Ochotona princeps	92.09	1.00e-76	277.00
IUUC-Ont-072562	Oreochromis niloticus	95.71	9.00e-80	287.00
IUUC-Ocu-073914	Oryctolagus cuniculus	97.14	4.00e-80	289.00
IUUC-Oba-075411	Oryza barthii	81.43	3.00e-68	249.00
IUUC-Obr-076658	Oryza brachyantha	80.00	3.00e-68	249.00
IUUC-Ogl-077772	Oryza glaberrima	81.43	3.00e-68	249.00
IUUC-Ogu-078981	Oryza glumaepatula	81.43	3.00e-68	249.00
IUUC-Oin-079652	Oryza indica	81.43	3.00e-68	249.00
IUUC-Olo-080786	Oryza longistaminata	81.43	3.00e-68	249.00
IUUC-Ome-081987	Oryza meridionalis	79.29	1.00e-67	247.00
IUUC-Oni-082391	Oryza nivara	73.12	5.00e-69	253.00
IUUC-Opu-083833	Oryza punctata	80.00	3.00e-68	249.00
IUUC-Oru-085167	Oryza rufipogon	73.12	6.00e-69	253.00
IUUC-Osa-086003	Oryza sativa	80.71	2.00e-68	249.00
IUUC-Ola-087515	Oryzias latipes	96.43	4.00e-80	288.00
IUUC-Olu-087615	Ostreococcus lucimarinus	77.14	2.00e-64	236.00
IUUC-Oga-088477	Otolemur garnettii	92.91	3.00e-78	283.00
IUUC-Oar-090038	Ovis aries	90.78	3.00e-77	279.00
IUUC-Ptr-090707	Pan troglodytes	92.86	1.00e-77	280.00
IUUC-Pan-092614	Papio anubis	100.00	3.00e-81	292.00
IUUC-Psi-094076	Pelodiscus sinensis	90.78	3.00e-77	279.00
IUUC-Pma-094405	Petromyzon marinus	93.23	2.00e-72	263.00
IUUC-Pno-094765	Phaeosphaeria nodorum	82.98	1.00e-70	257.00
IUUC-Ppa-095564	Physcomitrella patens	80.71	7.00e-68	248.00
IUUC-Pfo-096867	Poecilia formosa	96.43	4.00e-80	288.00
IUUC-Pab-098760	Pongo abelii	98.57	3.00e-81	293.00
IUUC-Pop-099853	Populus trichocarpa	80.71	3.00e-68	249.00
IUUC-Ppe-101431	Prunus persica	80.85	2.00e-68	250.00
IUUC-Pgr-103381	Puccinia graminis	79.43	1.00e-64	238.00
IUUC-Ptt-103723	Puccinia triticina	77.86	6.00e-61	225.00
IUUC-Pte-104015	Pyrenophora teres	82.98	2.00e-70	256.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	82.98	2.00e-70	256.00
IUUC-Rno-105498	Rattus norvegicus	90.78	3.00e-77	279.00
IUUC-Sce-106463	Saccharomyces cerevisiae	80.14	1.00e-68	251.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	82.98	2.00e-69	253.00
IUUC-Spo-108032	Schizosaccharomyces pombe	82.98	1.00e-69	254.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	82.98	6.00e-71	258.00
IUUC-Smo-108911	Selaginella moellendorffii	80.71	1.00e-67	247.00
IUUC-Sit-109936	Setaria italica	81.43	3.00e-69	253.00
IUUC-Sly-111614	Solanum lycopersicum	80.71	2.00e-68	249.00
IUUC-Stu-112436	Solanum tuberosum	80.71	1.00e-68	250.00
IUUC-Sar-113302	Sorex araneus	93.53	2.00e-77	279.00
IUUC-Sbi-114840	Sorghum bicolor	80.71	2.00e-68	250.00
IUUC-Sre-115037	Sporisorium reilianum	78.26	5.00e-65	238.00
IUUC-Ssc-115391	Sus scrofa	99.29	8.00e-82	294.00
IUUC-Tgu-116727	Taeniopygia guttata	90.78	3.00e-77	279.00
IUUC-Tru-118272	Takifugu rubripes	91.43	2.00e-76	276.00
IUUC-Tsy-118832	Tarsius syrichta	97.14	4.00e-79	285.00
IUUC-Tni-120056	Tetraodon nigroviridis	91.43	2.00e-76	276.00
IUUC-Tca-121542	Theobroma cacao	80.85	1.00e-69	254.00
IUUC-Tre-122125	Trichoderma reesei	80.14	3.00e-67	246.00
IUUC-Tvi-122296	Trichoderma virens	80.14	3.00e-67	246.00
IUUC-Tae-123340	Triticum aestivum	81.43	2.00e-69	253.00
IUUC-Tur-126518	Triticum urartu	79.29	9.00e-68	248.00
IUUC-Tme-126912	Tuber melanosporum	79.43	8.00e-68	248.00
IUUC-Tbe-128122	Tupaia belangeri	96.77	4.00e-61	225.00
IUUC-Uma-129648	Ustilago maydis	79.43	2.00e-67	246.00
IUUC-Vda-129695	Verticillium dahliae	82.98	5.00e-70	255.00
IUUC-Vpa-130446	Vicugna pacos	92.14	4.00e-76	276.00
IUUC-Vvi-131368	Vitis vinifera	80.14	2.00e-68	249.00
IUUC-Xtr-132238	Xenopus tropicalis	97.14	2.00e-80	290.00
IUUC-Xma-133829	Xiphophorus maculatus	91.43	7.00e-77	278.00
IUUC-Yli-134353	Yarrowia lipolytica	77.30	3.00e-67	246.00
IUUC-Zma-135956	Zea mays	79.29	1.00e-67	247.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence