iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088477

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03127040

Gene Name

UBE2D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000012860.2	ENSOGAT00000012863.2	ENSOGAP00000011526.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.00e-56	187.8	5	139
UBD/UBC-like/UBD_UBC	2.20e-84	280.5	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R+ +el++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  
   Q: 5    RISQELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR-- 90
           899*********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal++++vllsi+sll++pnp++pl  e+a+++k++r +y++ +r
   Q: 91   SQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRLAR 139
           *********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri +el+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqw
   Q: 5    RISQELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQW 93
           89*************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv+eiariyktd++ky+r arewt
   Q: 94   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRLAREWT 142
           ************************************************8 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

TAISRISQEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGCAATCT CTAGAATATC CCAGGGTATT CTTTTTTTTA TTGTATTGAG ACAAGAGTCT 60
CACTCTGTTG GCCTGGATAG AGTGCTGTAG TGTCATAGCT CATAGCACCC TCAAACTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001778	Ailuropoda melanoleuca	96.43	1.00e-79	288.00
IUUC-Atr-002861	Amborella trichopoda	78.77	1.00e-68	251.00
IUUC-Apl-004043	Anas platyrhynchos	95.92	8.00e-83	298.00
IUUC-Aca-005236	Anolis carolinensis	94.52	8.00e-82	295.00
IUUC-Aly-006221	Arabidopsis lyrata	78.77	5.00e-69	252.00
IUUC-Ath-007700	Arabidopsis thaliana	78.77	6.00e-68	249.00
IUUC-Acl-008266	Aspergillus clavatus	82.88	4.00e-72	262.00
IUUC-Afl-008709	Aspergillus flavus	78.87	2.00e-68	253.00
IUUC-Afu-008956	Aspergillus fumigatus	83.56	2.00e-72	264.00
IUUC-Ani-009401	Aspergillus nidulans	81.51	4.00e-71	259.00
IUUC-Ang-009725	Aspergillus niger	84.80	6.00e-62	229.00
IUUC-Aor-010157	Aspergillus oryzae	82.88	4.00e-72	263.00
IUUC-Ate-010438	Aspergillus terreus	82.19	2.00e-71	260.00
IUUC-Ame-011657	Astyanax mexicanus	93.20	8.00e-81	291.00
IUUC-Bgr-012238	Blumeria graminis	78.08	1.00e-67	248.00
IUUC-Bta-013158	Bos taurus	94.52	8.00e-82	295.00
IUUC-Bci-013661	Botrytis cinerea	81.51	5.00e-72	262.00
IUUC-Bdi-014561	Brachypodium distachyon	78.08	1.00e-68	251.00
IUUC-Bol-015722	Brassica oleracea	79.45	7.00e-69	252.00
IUUC-Bra-016748	Brassica rapa	77.40	2.00e-68	253.00
IUUC-Cel-018362	Caenorhabditis elegans	91.10	4.00e-79	286.00
IUUC-Cja-019886	Callithrix jacchus	94.52	8.00e-82	295.00
IUUC-Cfa-020436	Canis familiaris	94.52	8.00e-82	295.00
IUUC-Cpo-022334	Cavia porcellus	93.15	5.00e-80	289.00
IUUC-Csa-023377	Chlorocebus sabaeus	90.21	3.00e-77	280.00
IUUC-Cin-025379	Ciona intestinalis	84.83	6.00e-75	272.00
IUUC-Cgl-026490	Colletotrichum gloeosporioides	82.19	1.00e-71	261.00
IUUC-Dre-027758	Danio rerio	93.84	3.00e-81	293.00
IUUC-Dno-029156	Dasypus novemcinctus	95.10	1.00e-80	290.00
IUUC-Dor-030285	Dipodomys ordii	97.84	5.00e-80	289.00
IUUC-Dse-031397	Dothistroma septosporum	82.19	4.00e-72	262.00
IUUC-Dme-031594	Drosophila melanogaster	92.47	2.00e-79	287.00
IUUC-Ete-032295	Echinops telfairi	97.12	1.00e-79	287.00
IUUC-Eca-034286	Equus caballus	97.84	5.00e-80	289.00
IUUC-Eeu-034766	Erinaceus europaeus	99.29	3.00e-80	290.00
IUUC-Fca-035917	Felis catus	95.21	2.00e-82	296.00
IUUC-Fal-036904	Ficedula albicollis	97.14	3.00e-80	290.00
IUUC-Fox-038021	Fusarium oxysporum	82.19	1.00e-71	261.00
IUUC-Fso-038297	Fusarium solani	81.51	2.00e-71	260.00
IUUC-Gmo-038898	Gadus morhua	94.37	2.00e-79	287.00
IUUC-Ggr-039912	Gaeumannomyces graminis	77.48	3.00e-67	246.00
IUUC-Gga-041015	Gallus gallus	97.28	6.00e-84	302.00
IUUC-Gac-042516	Gasterosteus aculeatus	92.52	1.00e-79	287.00
IUUC-Gma-043733	Glycine max	78.77	1.00e-69	254.00
IUUC-Ggo-045375	Gorilla gorilla	96.45	2.00e-80	290.00
IUUC-Hsa-046157	Homo sapiens	95.21	2.00e-82	296.00
IUUC-Hvu-047546	Hordeum vulgare	76.03	5.00e-67	245.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	96.45	1.00e-80	291.00
IUUC-Lpe-051289	Leersia perrieri	78.08	2.00e-68	251.00
IUUC-Loc-052788	Lepisosteus oculatus	98.57	8.00e-81	291.00
IUUC-Lma-053121	Leptosphaeria maculans	82.19	3.00e-72	263.00
IUUC-Laf-053580	Loxodonta africana	96.43	7.00e-80	288.00
IUUC-Mcc-054672	Macaca mulatta	100.00	8.00e-82	295.00
IUUC-Meu-056462	Macropus eugenii	96.40	8.00e-79	285.00
IUUC-Mor-057235	Magnaporthe oryzae	81.51	4.00e-71	259.00
IUUC-Mpo-057596	Magnaporthe poae	77.48	7.00e-67	245.00
IUUC-Mtr-058532	Medicago truncatula	78.08	9.00e-68	248.00
IUUC-Mla-059189	Melampsora laricipopulina	78.77	1.00e-66	244.00
IUUC-Mga-059237	Meleagris gallopavo	95.77	3.00e-80	290.00
IUUC-Mmr-060889	Microcebus murinus	97.28	6.00e-84	302.00
IUUC-Mdo-062596	Monodelphis domestica	94.52	4.00e-82	296.00
IUUC-Mmu-063796	Mus musculus	97.28	6.00e-84	302.00
IUUC-Mpu-066604	Mustela putorius furo	93.15	3.00e-81	293.00
IUUC-Nfi-068599	Neosartorya fischeri	83.56	2.00e-72	264.00
IUUC-Ncr-068677	Neurospora crassa	80.82	3.00e-70	256.00
IUUC-Opr-070191	Ochotona princeps	97.84	5.00e-80	289.00
IUUC-Ont-071766	Oreochromis niloticus	93.15	7.00e-81	291.00
IUUC-Oan-073026	Ornithorhynchus anatinus	92.91	5.00e-78	283.00
IUUC-Ocu-074315	Oryctolagus cuniculus	94.52	8.00e-82	295.00
IUUC-Oba-075411	Oryza barthii	78.08	2.00e-68	250.00
IUUC-Obr-076658	Oryza brachyantha	78.08	2.00e-68	250.00
IUUC-Ogu-078981	Oryza glumaepatula	78.08	2.00e-68	250.00
IUUC-Olo-080786	Oryza longistaminata	78.08	2.00e-68	250.00
IUUC-Ome-081987	Oryza meridionalis	77.40	1.00e-67	248.00
IUUC-Opu-083833	Oryza punctata	78.08	2.00e-68	250.00
IUUC-Ola-086331	Oryzias latipes	93.15	7.00e-81	291.00
IUUC-Olu-087615	Ostreococcus lucimarinus	75.68	6.00e-65	239.00
IUUC-Oar-090038	Ovis aries	95.21	2.00e-82	296.00
IUUC-Ptr-090707	Pan troglodytes	94.52	8.00e-82	295.00
IUUC-Pan-092143	Papio anubis	94.52	8.00e-82	295.00
IUUC-Psi-094076	Pelodiscus sinensis	95.21	2.00e-82	296.00
IUUC-Pma-094405	Petromyzon marinus	95.56	2.00e-75	273.00
IUUC-Pno-094765	Phaeosphaeria nodorum	82.19	3.00e-72	263.00
IUUC-Pfo-096753	Poecilia formosa	93.15	7.00e-81	291.00
IUUC-Pab-097764	Pongo abelii	94.52	8.00e-82	295.00
IUUC-Pop-098799	Populus trichocarpa	78.77	2.00e-68	250.00
IUUC-Ppe-101431	Prunus persica	79.45	7.00e-69	252.00
IUUC-Pgr-103381	Puccinia graminis	80.14	2.00e-67	248.00
IUUC-Ptt-103723	Puccinia triticina	78.57	2.00e-61	228.00
IUUC-Pte-104015	Pyrenophora teres	82.19	4.00e-72	263.00
IUUC-Pyt-104701	Pyrenophora triticirepentis	82.19	4.00e-72	263.00
IUUC-Rno-105498	Rattus norvegicus	95.21	2.00e-82	296.00
IUUC-Sce-106463	Saccharomyces cerevisiae	80.42	2.00e-69	254.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	82.88	3.00e-71	259.00
IUUC-Spo-108032	Schizosaccharomyces pombe	82.88	1.00e-71	261.00
IUUC-Ssl-108443	Sclerotinia sclerotiorum	82.19	2.00e-72	264.00
IUUC-Sit-109936	Setaria italica	77.40	1.00e-68	252.00
IUUC-Sar-113302	Sorex araneus	97.12	1.00e-79	287.00
IUUC-Sbi-114840	Sorghum bicolor	78.77	7.00e-69	252.00
IUUC-Sre-115037	Sporisorium reilianum	79.02	1.00e-67	248.00
IUUC-Ssc-116154	Sus scrofa	93.88	2.00e-81	293.00
IUUC-Tgu-116727	Taeniopygia guttata	95.21	2.00e-82	296.00
IUUC-Tru-118272	Takifugu rubripes	93.15	2.00e-80	290.00
IUUC-Tsy-118832	Tarsius syrichta	88.36	8.00e-77	278.00
IUUC-Tni-120056	Tetraodon nigroviridis	93.15	2.00e-80	290.00
IUUC-Tca-121542	Theobroma cacao	77.40	6.00e-69	253.00
IUUC-Tre-122125	Trichoderma reesei	80.14	2.00e-69	254.00
IUUC-Tvi-122296	Trichoderma virens	80.14	2.00e-69	254.00
IUUC-Tme-126912	Tuber melanosporum	80.14	7.00e-70	255.00
IUUC-Tbe-127609	Tupaia belangeri	97.44	9.00e-67	244.00
IUUC-Uma-129648	Ustilago maydis	80.14	1.00e-69	254.00
IUUC-Vda-129695	Verticillium dahliae	82.19	1.00e-71	261.00
IUUC-Vpa-130446	Vicugna pacos	95.71	2.00e-78	285.00
IUUC-Vvi-131368	Vitis vinifera	78.77	7.00e-69	252.00
IUUC-Xtr-132329	Xenopus tropicalis	94.52	8.00e-82	295.00
IUUC-Xma-133829	Xiphophorus maculatus	93.15	7.00e-81	291.00
IUUC-Yli-134353	Yarrowia lipolytica	77.40	3.00e-69	253.00
IUUC-Zma-135956	Zea mays	77.40	1.00e-67	248.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence