• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063976
UUCD1 version UUC-MuM-00922
Ensembl Protein ID ENSMUSP00000048489.6
UniProt Accession Q9D2V7; Q3UDJ4; Q6P8Y8; Q8C9V7; CORO7_MOUSE
Genbank Protein ID BAB31380.1; BAC30588.1; BAE29267.1; AAH61006.1
Protein Name Coronin-7; 70 kDa WD repeat tumor rejection antigen homolog
Genbank Nucleotide ID AK018739; AK040408; AK150051; BC061006
Gene Name Coro7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000039637.14 ENSMUST00000038552.12 ENSMUSP00000048489.6
ENSMUSG00000039637.14 ENSMUST00000135823.7 ENSMUSP00000118310.1
ENSMUSG00000039637.14 ENSMUST00000090480.4 ENSMUSP00000087966.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.30e-32 109.3 632 668
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH+d +++la+ +d + l++ + Dg ++v+++r+ +l
   Q: 632  GHQDQIFSLAWsPDgKQLATVCKDGHVRVYEPRSSPL 668
           8***********999****************998766 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology (By similarity).
 F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology (By similarity).
Protein Sequence
(Fasta)
MSRFKVSKFR HMEARPSRRE AWISDIRAVT TPTCGNHIKS SCSLIAFNSD RPGVLGVISL 60
EGHEENKRHV TYLGCHSDLV TDLDFSPFDD FLLASGSADR TIKLWRLSGT GEALPSVPGV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063976|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGGCAGGCCG CAGGAGCTTC CGATTGGTTG TCATCAATAA GGGCGTGGCA CCAGGCTGCA 60
GGCTGCTGAG GCGGCAGGCT GCAAGAGTCC AGGGCGGCTT CTCTTCATTC ACCTAGTACC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063976|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0009--Actin-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0333--Golgi apparatus
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0832--Ubl conjugation
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027331--CORO7
IPR015505--Coronin
IPR015048--DUF1899
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08953--DUF1899
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM01166--DUF1899
SM00320--WD40
Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0016020--C:membrane
GO:0005802--C:trans-Golgi network
GO:0003779--F:actin binding
GO:0007015--P:actin filament organization
GO:0030041--P:actin filament polymerization
GO:0016477--P:cell migration
GO:0030010--P:establishment of cell polarity
GO:0007030--P:Golgi organization
GO:0006895--P:Golgi to endosome transport
GO:0015031--P:protein transport
KEGG mmu:78885
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002235 Ailuropoda melanoleuca 88.63 0.00e+00 763.00
IUUC-Apl-004126 Anas platyrhynchos 57.30 7.00e-115 408.00
IUUC-Aca-005201 Anolis carolinensis 66.86 0.00e+00 799.00
IUUC-Ame-011310 Astyanax mexicanus 53.87 7.00e-77 280.00
IUUC-Bta-012843 Bos taurus 81.04 0.00e+00 1372.00
IUUC-Cel-018204 Caenorhabditis elegans 35.87 4.00e-70 259.00
IUUC-Cja-019024 Callithrix jacchus 81.51 0.00e+00 1296.00
IUUC-Cfa-020626 Canis familiaris 82.34 0.00e+00 1368.00
IUUC-Cpo-022429 Cavia porcellus 82.65 0.00e+00 1460.00
IUUC-Csa-023919 Chlorocebus sabaeus 83.77 0.00e+00 1393.00
IUUC-Cin-025202 Ciona intestinalis 45.18 2.00e-119 423.00
IUUC-Csv-026236 Ciona savignyi 40.99 3.00e-135 475.00
IUUC-Dre-028759 Danio rerio 68.58 0.00e+00 636.00
IUUC-Dno-029234 Dasypus novemcinctus 70.98 0.00e+00 999.00
IUUC-Dor-030242 Dipodomys ordii 84.72 0.00e+00 1410.00
IUUC-Dme-032156 Drosophila melanogaster 45.26 3.00e-119 423.00
IUUC-Ete-032862 Echinops telfairi 77.60 0.00e+00 1221.00
IUUC-Eca-033902 Equus caballus 80.55 0.00e+00 1311.00
IUUC-Eeu-034540 Erinaceus europaeus 65.51 2.00e-179 622.00
IUUC-Fca-036335 Felis catus 82.30 0.00e+00 1392.00
IUUC-Fal-037278 Ficedula albicollis 72.40 0.00e+00 691.00
IUUC-Gmo-038846 Gadus morhua 67.11 5.00e-173 601.00
IUUC-Gga-041144 Gallus gallus 60.26 0.00e+00 1021.00
IUUC-Gac-041680 Gasterosteus aculeatus 53.18 0.00e+00 936.00
IUUC-Ggo-045469 Gorilla gorilla 81.47 4.00e-180 625.00
IUUC-Hsa-046873 Homo sapiens 83.77 0.00e+00 1374.00
IUUC-Itr-048351 Ictidomys tridecemlineatus 84.71 0.00e+00 1450.00
IUUC-Loc-052682 Lepisosteus oculatus 62.83 0.00e+00 851.00
IUUC-Laf-053869 Loxodonta africana 71.00 0.00e+00 956.00
IUUC-Mcc-054896 Macaca mulatta 83.98 0.00e+00 1412.00
IUUC-Meu-056428 Macropus eugenii 73.13 0.00e+00 1272.00
IUUC-Mla-058813 Melampsora laricipopulina 26.97 2.00e-64 240.00
IUUC-Mga-059389 Meleagris gallopavo 63.68 0.00e+00 1110.00
IUUC-Mvi-060231 Microbotryum violaceum 33.63 5.00e-58 219.00
IUUC-Mmr-060935 Microcebus murinus 85.75 0.00e+00 1421.00
IUUC-Mdo-062707 Monodelphis domestica 73.84 0.00e+00 1321.00
IUUC-Mpu-066441 Mustela putorius furo 89.27 0.00e+00 751.00
IUUC-Mlu-067524 Myotis lucifugus 84.18 0.00e+00 1436.00
IUUC-Opr-071099 Ochotona princeps 80.32 0.00e+00 1242.00
IUUC-Ont-071673 Oreochromis niloticus 66.45 0.00e+00 639.00
IUUC-Oan-072860 Ornithorhynchus anatinus 74.40 0.00e+00 810.00
IUUC-Ocu-074794 Oryctolagus cuniculus 83.15 0.00e+00 1356.00
IUUC-Ola-086479 Oryzias latipes 55.02 0.00e+00 984.00
IUUC-Oga-088030 Otolemur garnettii 89.18 0.00e+00 742.00
IUUC-Oar-090379 Ovis aries 72.48 0.00e+00 1125.00
IUUC-Ptr-091006 Pan troglodytes 79.57 0.00e+00 1283.00
IUUC-Pan-092428 Papio anubis 83.78 0.00e+00 1407.00
IUUC-Psi-093624 Pelodiscus sinensis 54.45 5.00e-115 407.00
IUUC-Pfo-096558 Poecilia formosa 55.34 0.00e+00 993.00
IUUC-Pab-098298 Pongo abelii 75.56 0.00e+00 1138.00
IUUC-Pca-100305 Procavia capensis 73.71 0.00e+00 890.00
IUUC-Pva-102702 Pteropus vampyrus 81.71 0.00e+00 1150.00
IUUC-Pgr-103449 Puccinia graminis 26.75 4.00e-68 253.00
IUUC-Rno-105934 Rattus norvegicus 89.06 0.00e+00 1552.00
IUUC-Sha-106795 Sarcophilus harrisii 71.40 0.00e+00 1201.00
IUUC-Sar-112987 Sorex araneus 83.02 6.00e-109 388.00
IUUC-Ssc-116071 Sus scrofa 82.12 0.00e+00 1398.00
IUUC-Tgu-116813 Taeniopygia guttata 73.39 5.00e-136 478.00
IUUC-Tru-118359 Takifugu rubripes 66.38 0.00e+00 652.00
IUUC-Tni-119997 Tetraodon nigroviridis 65.59 0.00e+00 647.00
IUUC-Ttr-129020 Tursiops truncatus 79.63 0.00e+00 1385.00
IUUC-Xtr-132552 Xenopus tropicalis 63.47 4.00e-121 427.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved