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Tag Content
iUUCD ID IUUC-Mdo-062196
Ensembl Protein ID ENSMODP00000037509.2
UniProt Accession F7BED1; F7BED1_MONDO
Protein Name Uncharacterized protein
Gene Name PML
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMODG00000009808.3 ENSMODT00000039107.2 ENSMODP00000037509.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 46.78 0.00e+00 662.00 IUUC-Hsa-045861
E3 activity/RING/RING 43.76 1.00e-168 592.00 IUUC-Mmu-063118
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Monodelphis domestica
Protein Sequence
(Fasta)
MDGWMVPQSQ LHLRRGAGST VLEKERESKR LGSFPCIHTH PGGLPRPSPL PHSPAFQPGH 60
LGEALPRGTG LPPHQGPAAS WSVTSSRSPA GDRQGKRRSQ KKLHRPVFFL RAPSSPGGLC 120
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Protein Fasta Sequence



>IUUC-Mdo-062196|E3,RING|Monodelphis domestica
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Nucleotide Sequence
(Fasta)
ATGGATGGTT GGATGGTCCC GCAGTCTCAG CTCCACCTAC GCCGGGGGGC CGGGAGCACC 60
GTCCTGGAAA AAGAAAGAGA AAGCAAGAGG CTGGGGTCCT TCCCGTGCAT ACACACACAC 120
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Nucleotide Fasta Sequence



>IUUC-Mdo-062196|E3,RING|Monodelphis domestica
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021978--DUF3583
IPR012337--RNaseH-like_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12126--DUF3583
PF00643--zf-B_box

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0042406--C:extrinsic component of endoplasmic reticulum membrane
GO:0000784--C:nuclear chromosome, telomeric region
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0007050--P:cell cycle arrest
GO:0045165--P:cell fate commitment
GO:0071353--P:cellular response to interleukin-4
GO:0090398--P:cellular senescence
GO:0032922--P:circadian regulation of gene expression
GO:0007182--P:common-partner SMAD protein phosphorylation
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0032469--P:endoplasmic reticulum calcium ion homeostasis
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0010761--P:fibroblast migration
GO:0045087--P:innate immune response
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0051457--P:maintenance of protein location in nucleus
GO:0030099--P:myeloid cell differentiation
GO:0016525--P:negative regulation of angiogenesis
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0050713--P:negative regulation of interleukin-1 beta secretion
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1902187--P:negative regulation of viral release from host cell
GO:0030578--P:PML body organization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0045345--P:positive regulation of MHC class I biosynthetic process
GO:0032206--P:positive regulation of telomere maintenance
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006461--P:protein complex assembly
GO:0010522--P:regulation of calcium ion transport into cytosol
GO:0030155--P:regulation of cell adhesion
GO:2000779--P:regulation of double-strand break repair
GO:0001932--P:regulation of protein phosphorylation
GO:0010332--P:response to gamma radiation
GO:0001666--P:response to hypoxia
GO:0009411--P:response to UV
GO:0048384--P:retinoic acid receptor signaling pathway
GO:0007184--P:SMAD protein import into nucleus
GO:0007179--P:transforming growth factor beta receptor signaling pathway

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001901 Ailuropoda melanoleuca 46.62 0.00e+00 630.00
IUUC-Bta-012427 Bos taurus 45.08 0.00e+00 647.00
IUUC-Cja-019029 Callithrix jacchus 47.27 0.00e+00 653.00
IUUC-Cfa-021127 Canis familiaris 45.70 2.00e-179 622.00
IUUC-Cpo-022553 Cavia porcellus 46.18 9.00e-179 620.00
IUUC-Csa-023187 Chlorocebus sabaeus 47.27 2.00e-124 439.00
IUUC-Cho-024937 Choloepus hoffmanni 53.40 5.00e-57 216.00
IUUC-Dno-029326 Dasypus novemcinctus 45.61 0.00e+00 628.00
IUUC-Dor-030808 Dipodomys ordii 39.77 2.00e-107 383.00
IUUC-Ete-032746 Echinops telfairi 45.95 2.00e-58 220.00
IUUC-Eca-033234 Equus caballus 46.34 4.00e-177 615.00
IUUC-Fca-035648 Felis catus 47.23 0.00e+00 655.00
IUUC-Ggo-044927 Gorilla gorilla 47.39 0.00e+00 682.00
IUUC-Hsa-045861 Homo sapiens 47.39 0.00e+00 681.00
IUUC-Itr-047861 Ictidomys tridecemlineatus 47.24 0.00e+00 693.00
IUUC-Loc-052276 Lepisosteus oculatus 34.72 4.00e-52 199.00
IUUC-Laf-054059 Loxodonta africana 46.73 0.00e+00 645.00
IUUC-Meu-056495 Macropus eugenii 84.26 3.00e-166 578.00
IUUC-Mga-059224 Meleagris gallopavo 39.09 2.00e-46 181.00
IUUC-Mmr-061507 Microcebus murinus 47.16 0.00e+00 671.00
IUUC-Mmu-063118 Mus musculus 43.14 0.00e+00 630.00
IUUC-Mpu-066024 Mustela putorius furo 44.93 6.00e-179 621.00
IUUC-Mlu-066980 Myotis lucifugus 46.55 0.00e+00 647.00
IUUC-Nle-069779 Nomascus leucogenys 46.63 0.00e+00 659.00
IUUC-Ocu-074016 Oryctolagus cuniculus 44.42 4.00e-171 595.00
IUUC-Oga-089085 Otolemur garnettii 44.67 1.00e-175 610.00
IUUC-Oar-089980 Ovis aries 43.49 2.00e-173 602.00
IUUC-Ptr-091681 Pan troglodytes 47.28 0.00e+00 675.00
IUUC-Pan-091965 Papio anubis 47.80 0.00e+00 658.00
IUUC-Psi-093577 Pelodiscus sinensis 50.42 3.00e-83 303.00
IUUC-Pab-098215 Pongo abelii 52.57 7.00e-107 381.00
IUUC-Pca-100883 Procavia capensis 40.53 2.00e-121 429.00
IUUC-Pva-102465 Pteropus vampyrus 44.20 2.00e-118 420.00
IUUC-Rno-105120 Rattus norvegicus 41.24 2.00e-176 613.00
IUUC-Sar-113320 Sorex araneus 48.36 7.00e-56 212.00
IUUC-Ssc-116042 Sus scrofa 46.20 0.00e+00 647.00
IUUC-Tbe-127880 Tupaia belangeri 52.48 3.00e-98 352.00
Created Date 25-Jun-2017

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