iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004722

Ensembl Protein ID

ENSACAP00000008364.3

UniProt Accession

H9GE04; H9GE04_ANOCA

Protein Name

Uncharacterized protein

Gene Name

BRWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000008361.3	ENSACAT00000008545.3	ENSACAP00000008364.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-31	105.6	7	44
UBD/Beta-Prp	1.90e-53	181.5	109	368

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  s++++ +GsdD+ +k+W ++ g+ll
   Q: 7    GHLSSVYCVAFdrSGRRIFTGSDDCLVKIWATDNGRLL 44
           8**********96669***************9999887 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl........lrslsgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++l+++++dgti  w+++  ++        +++ s    ++++ +fs+ g +++tgs+D++i+++    ++++ +  l+ h+d+v+++
   Q: 109  TRYLTSTGADGTICFWQWHLNTMkfkdrpvkFAERSRPGVQISCSSFSSGGMFIATGSTDHVIRIYylGSESPEKIAELESHTDKVVAV 197
           589************999986665577764444444444449************************88888****************** PP
   S: 101  sfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkl 171
           +f+ +g   ++vsGs+d t+rvw+ +++++ +                  +++ +  v++v+++  ++ ++++ ++  +++W+++tg+l
   Q: 198  QFCNNGdrLRFVSGSRDGTARVWQYQQQEWKNIvldmatkmtgnslqsgEDKVSKLKVTMVAWDRYDSTVITAVNNFLLKVWNSSTGQL 286
           ****8822468********************99************888777777888******************************** PP
   S: 172  lrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiri 248
           l+ l+g h+d v  l+   fd+  + ++s+++dg + +wdl++g+ +r + +         v + +fsp++++++++ s+g + +
   Q: 287  LHSLSG-HDDEVFVLEahpFDQ--RIMLSAGHDGNIFIWDLEKGTKIRNYFNMIegqghGAVFDCKFSPDGQHFACTDSHGHLLL 368
           *****9.*********555555..999*******************988877554555577778899999999999999887765 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MHKRILGHLS SVYCVAFDRS GRRIFTGSDD CLVKIWATDN GRLLSTLRGH SAEISDMAVS 60
YENTLLAAGS CDKVVRVWCL RTCAPVAVLL GHSASITSIQ FSPARKGTTR YLTSTGADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGCAGGCA CACGGCATGG AAGGGATCAA CCTTTGCAGC ACTCCACAGA GGCAGGCCTC 60
CAGAACTACC TGTAAATTAC GGAAAACCAC CAAATGTGGG TAAGGAATAC TCTTATCATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	79.45	0.00e+00	2247.00
IUUC-Apl-004016	Anas platyrhynchos	86.90	0.00e+00	2217.00
IUUC-Ame-010602	Astyanax mexicanus	68.79	0.00e+00	1726.00
IUUC-Bta-013198	Bos taurus	78.70	0.00e+00	2237.00
IUUC-Cfa-020963	Canis familiaris	79.12	0.00e+00	2238.00
IUUC-Cpo-022448	Cavia porcellus	73.22	0.00e+00	2075.00
IUUC-Csa-023166	Chlorocebus sabaeus	79.24	0.00e+00	2228.00
IUUC-Cin-025553	Ciona intestinalis	41.73	1.00e-119	423.00
IUUC-Dre-028508	Danio rerio	69.69	0.00e+00	1686.00
IUUC-Dno-030070	Dasypus novemcinctus	78.20	0.00e+00	2164.00
IUUC-Dor-031052	Dipodomys ordii	73.48	0.00e+00	959.00
IUUC-Ete-032650	Echinops telfairi	80.00	0.00e+00	1490.00
IUUC-Eca-033953	Equus caballus	79.53	0.00e+00	2249.00
IUUC-Eeu-034871	Erinaceus europaeus	70.90	0.00e+00	934.00
IUUC-Fca-036099	Felis catus	78.53	0.00e+00	2228.00
IUUC-Fal-037246	Ficedula albicollis	86.46	0.00e+00	2370.00
IUUC-Gmo-039116	Gadus morhua	66.53	5.00e-169	588.00
IUUC-Gga-041097	Gallus gallus	87.37	0.00e+00	2401.00
IUUC-Gac-042435	Gasterosteus aculeatus	64.82	0.00e+00	1615.00
IUUC-Hsa-045666	Homo sapiens	78.77	0.00e+00	2229.00
IUUC-Loc-051802	Lepisosteus oculatus	70.18	0.00e+00	1873.00
IUUC-Laf-053942	Loxodonta africana	79.34	0.00e+00	2240.00
IUUC-Mcc-054645	Macaca mulatta	79.24	0.00e+00	2231.00
IUUC-Meu-056321	Macropus eugenii	71.40	0.00e+00	864.00
IUUC-Mga-060063	Meleagris gallopavo	86.82	0.00e+00	2368.00
IUUC-Mmr-061262	Microcebus murinus	79.29	0.00e+00	2221.00
IUUC-Mdo-062320	Monodelphis domestica	70.21	0.00e+00	2063.00
IUUC-Mmu-063163	Mus musculus	78.08	0.00e+00	2201.00
IUUC-Mpu-066628	Mustela putorius furo	79.41	0.00e+00	2229.00
IUUC-Mlu-068082	Myotis lucifugus	79.37	0.00e+00	2190.00
IUUC-Nle-069609	Nomascus leucogenys	79.04	0.00e+00	2230.00
IUUC-Ont-071589	Oreochromis niloticus	65.23	0.00e+00	1646.00
IUUC-Ocu-074122	Oryctolagus cuniculus	79.65	0.00e+00	1768.00
IUUC-Ola-086580	Oryzias latipes	66.61	0.00e+00	1665.00
IUUC-Oga-089053	Otolemur garnettii	78.67	0.00e+00	2231.00
IUUC-Oar-090042	Ovis aries	78.95	0.00e+00	2237.00
IUUC-Ptr-091268	Pan troglodytes	78.63	0.00e+00	2229.00
IUUC-Pan-092376	Papio anubis	79.24	0.00e+00	2230.00
IUUC-Psi-093408	Pelodiscus sinensis	85.32	0.00e+00	2600.00
IUUC-Pfo-096515	Poecilia formosa	67.33	0.00e+00	1586.00
IUUC-Pab-097672	Pongo abelii	78.97	0.00e+00	2237.00
IUUC-Pva-102512	Pteropus vampyrus	85.58	0.00e+00	1819.00
IUUC-Rno-105797	Rattus norvegicus	78.20	0.00e+00	2193.00
IUUC-Sha-107061	Sarcophilus harrisii	72.96	0.00e+00	2168.00
IUUC-Tgu-117254	Taeniopygia guttata	86.09	0.00e+00	2350.00
IUUC-Tru-118186	Takifugu rubripes	66.07	0.00e+00	1635.00
IUUC-Tsy-119003	Tarsius syrichta	74.30	0.00e+00	2048.00
IUUC-Tni-120110	Tetraodon nigroviridis	65.87	0.00e+00	1620.00
IUUC-Ttr-129265	Tursiops truncatus	77.20	0.00e+00	2170.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence