iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048236

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01084340

Gene Name

TBL1Y

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000014293.2	ENSSTOT00000014297.2	ENSSTOP00000012804.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-55	182.2	299	337
UBD/Beta-Prp	5.60e-65	219.4	170	371

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g l++s
   Q: 299  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGSLVHS 337
           9**********999******************9999875 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
            +v++ ++++ +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h+++++++++
   Q: 170  LDVDW-QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKW 257
           33444.55555666666666666666665666666666666666666666666666666666666666666666666666666666555 PP
   S: 103  sp.........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           sp         s+  l+s+s d+t+r+wd+e g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ 
   Q: 258  SPtgpatsnpnSNIMLASASFDSTVRLWDVERGVCIH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG--TGG 343
           5544444433222455666666666666666666666.6666666666666666666666666666666666666666666655..666 PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlq 210
           +  + ++  g  + + + dg+v + dl+
   Q: 344  IFEVCWNARGDKVGASASDGSVCVLDLR 371
           6666666666666666666666555554 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

DNHSKPMEID GDVEIPPNKA TVLRGHESEV FICAWNPVSD LLASGSGDST ARIWNLNENS 60
NGGSTQLVLR HCIREGGHDV PSNKDVTSLD WNSDGTLLAT GSYDGFARIW TEDGNLASTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATAACCATT CGAAACCAAT GGAAATAGAT GGGGATGTTG AAATTCCACC CAACAAAGCC 60
ACAGTCCTTC GGGGCCATGA GTCTGAGGTG TTCATTTGTG CCTGGAATCC GGTCAGCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001450	Ailuropoda melanoleuca	99.46	0.00e+00	776.00
IUUC-Apl-003232	Anas platyrhynchos	98.39	0.00e+00	769.00
IUUC-Aca-005035	Anolis carolinensis	97.58	0.00e+00	766.00
IUUC-Ago-007869	Ashbya gossypii	27.68	1.00e-32	134.00
IUUC-Bta-013202	Bos taurus	98.92	0.00e+00	773.00
IUUC-Cja-019281	Callithrix jacchus	95.43	0.00e+00	753.00
IUUC-Cfa-020929	Canis familiaris	99.73	0.00e+00	777.00
IUUC-Cpo-021682	Cavia porcellus	98.92	0.00e+00	768.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.43	3.00e-130	458.00
IUUC-Csa-023943	Chlorocebus sabaeus	95.43	0.00e+00	756.00
IUUC-Cin-025704	Ciona intestinalis	77.92	0.00e+00	632.00
IUUC-Csv-026257	Ciona savignyi	78.76	3.00e-179	621.00
IUUC-Cne-026946	Cryptococcus neoformans	38.01	3.00e-30	126.00
IUUC-Dno-028926	Dasypus novemcinctus	97.85	0.00e+00	763.00
IUUC-Dme-031939	Drosophila melanogaster	81.74	1.00e-174	606.00
IUUC-Ete-032822	Echinops telfairi	83.87	1.00e-179	622.00
IUUC-Eca-033897	Equus caballus	99.73	0.00e+00	777.00
IUUC-Fca-036462	Felis catus	99.46	0.00e+00	777.00
IUUC-Fal-037388	Ficedula albicollis	98.66	0.00e+00	771.00
IUUC-Gga-040671	Gallus gallus	98.66	0.00e+00	771.00
IUUC-Ggo-045373	Gorilla gorilla	95.97	0.00e+00	760.00
IUUC-Hsa-045841	Homo sapiens	95.97	0.00e+00	760.00
IUUC-Lch-050535	Latimeria chalumnae	95.70	0.00e+00	750.00
IUUC-Loc-052722	Lepisosteus oculatus	95.16	0.00e+00	746.00
IUUC-Laf-054071	Loxodonta africana	98.66	0.00e+00	771.00
IUUC-Mcc-055233	Macaca mulatta	95.07	0.00e+00	741.00
IUUC-Mga-059895	Meleagris gallopavo	98.66	0.00e+00	771.00
IUUC-Mmr-061286	Microcebus murinus	99.46	0.00e+00	776.00
IUUC-Mmu-063447	Mus musculus	99.19	0.00e+00	774.00
IUUC-Mpu-066869	Mustela putorius furo	99.45	0.00e+00	756.00
IUUC-Mlu-067852	Myotis lucifugus	98.39	0.00e+00	766.00
IUUC-Nle-069151	Nomascus leucogenys	95.97	0.00e+00	760.00
IUUC-Ont-072252	Oreochromis niloticus	93.28	0.00e+00	728.00
IUUC-Oan-073562	Ornithorhynchus anatinus	99.19	0.00e+00	775.00
IUUC-Olu-087589	Ostreococcus lucimarinus	60.42	2.00e-135	475.00
IUUC-Oar-089506	Ovis aries	99.19	0.00e+00	773.00
IUUC-Ptr-090793	Pan troglodytes	95.15	0.00e+00	734.00
IUUC-Pan-091909	Papio anubis	95.47	0.00e+00	757.00
IUUC-Psi-093358	Pelodiscus sinensis	99.19	0.00e+00	773.00
IUUC-Pab-098317	Pongo abelii	95.86	0.00e+00	741.00
IUUC-Rno-105857	Rattus norvegicus	99.19	0.00e+00	774.00
IUUC-Sha-107326	Sarcophilus harrisii	98.92	0.00e+00	774.00
IUUC-Stu-112786	Solanum tuberosum	56.23	5.00e-121	427.00
IUUC-Ssc-115646	Sus scrofa	99.73	0.00e+00	779.00
IUUC-Tgu-116898	Taeniopygia guttata	98.66	0.00e+00	771.00
IUUC-Tsy-118853	Tarsius syrichta	77.69	9.00e-166	576.00
IUUC-Tni-119656	Tetraodon nigroviridis	94.09	0.00e+00	718.00
IUUC-Ttr-128826	Tursiops truncatus	99.39	0.00e+00	691.00
IUUC-Uma-129469	Ustilago maydis	43.53	5.00e-58	219.00
IUUC-Vvi-131193	Vitis vinifera	58.73	9.00e-128	450.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence