iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097870

Ensembl Protein ID

ENSPPYP00000016727.2

UniProt Accession

Q5RCV7; INT12_PONAB

Genbank Protein ID

CAH90400.1

Protein Name

Integrator complex subunit 12; PHD finger protein 22

Genbank Nucleotide ID

CR858161

Gene Name

INTS12; PHF22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000014977.2	ENSPPYT00000017406.2	ENSPPYP00000016727.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.70e-09	35.9	162	214

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 4    ClvCgeggedek.slveCekCrewfHpaClklsveeelpnsek..wiCpkCrs 53
           C vC++ +  +  +lveC++C++ +H +C+k++v ++  n+ +  w+C +C++
   Q: 162  CVVCRQMMVASGnQLVECQECHNLYHRDCHKPQVTDKEANDPRlvWYCARCTR 214
           ********98866********************999999987799******86 PP

Organism

Pongo abelii

Functional Description
(View)

Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (By similarity).

Protein Sequence
(Fasta)

MAATVNLELD PIFLKALGFL HSKSKDSAEK LKALLDESLA RGIDSSYRPS QKDVEPPKIS 60
STKNISIKQE PKISSSLPSG NNNGKVLTTE KVKKEAEKRP ADKMKSDITE GVDIPKKPRL 120

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Nucleotide Sequence
(Fasta)

CTGCTTTCGG AGCCGGCCAG TGGGGGGACC GTTTCCGAAG GGACCACCGG GAACAGACGG 60
ATCGGCAGGG CGGGGCGGAA CGGTGAGTTA TGCTGAGCGA CTCTGCTCCC GGCCTCCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding

KEGG

pon:100172088

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001485	Ailuropoda melanoleuca	92.90	7.00e-174	603.00
IUUC-Apl-003539	Anas platyrhynchos	78.59	6.00e-149	520.00
IUUC-Bta-013090	Bos taurus	91.35	7.00e-156	543.00
IUUC-Cja-019984	Callithrix jacchus	96.67	3.00e-174	604.00
IUUC-Cfa-020068	Canis familiaris	93.13	2.00e-178	618.00
IUUC-Cpo-021446	Cavia porcellus	87.36	2.00e-142	498.00
IUUC-Csa-023385	Chlorocebus sabaeus	98.45	3.00e-180	624.00
IUUC-Cho-025018	Choloepus hoffmanni	93.35	1.00e-163	569.00
IUUC-Dre-027546	Danio rerio	64.04	4.00e-95	341.00
IUUC-Dno-029989	Dasypus novemcinctus	93.13	1.00e-161	562.00
IUUC-Eca-033999	Equus caballus	90.24	6.00e-161	560.00
IUUC-Fca-035522	Felis catus	94.46	4.00e-169	587.00
IUUC-Gga-041056	Gallus gallus	75.55	5.00e-147	513.00
IUUC-Gac-042508	Gasterosteus aculeatus	59.05	1.00e-87	316.00
IUUC-Ggo-044647	Gorilla gorilla	99.25	3.00e-140	491.00
IUUC-Hsa-046655	Homo sapiens	99.56	1.00e-172	599.00
IUUC-Loc-052933	Lepisosteus oculatus	70.87	7.00e-98	350.00
IUUC-Laf-054471	Loxodonta africana	92.90	3.00e-173	601.00
IUUC-Mcc-055568	Macaca mulatta	98.45	3.00e-180	624.00
IUUC-Meu-056037	Macropus eugenii	89.24	2.00e-152	531.00
IUUC-Mga-059569	Meleagris gallopavo	74.67	8.00e-145	506.00
IUUC-Mmr-061180	Microcebus murinus	94.68	4.00e-166	577.00
IUUC-Mdo-062528	Monodelphis domestica	86.88	1.00e-156	546.00
IUUC-Mmu-064122	Mus musculus	90.91	6.00e-153	533.00
IUUC-Mpu-066477	Mustela putorius furo	93.79	1.00e-165	576.00
IUUC-Mlu-067391	Myotis lucifugus	93.57	4.00e-163	567.00
IUUC-Nle-069599	Nomascus leucogenys	99.11	5.00e-165	573.00
IUUC-Opr-070713	Ochotona princeps	90.69	2.00e-142	498.00
IUUC-Ont-072565	Oreochromis niloticus	63.17	2.00e-82	299.00
IUUC-Oan-073115	Ornithorhynchus anatinus	84.39	8.00e-111	392.00
IUUC-Ocu-074717	Oryctolagus cuniculus	93.79	2.00e-162	565.00
IUUC-Ola-087458	Oryzias latipes	68.20	3.00e-86	312.00
IUUC-Oga-088704	Otolemur garnettii	95.12	3.00e-164	571.00
IUUC-Oar-089184	Ovis aries	92.46	9.00e-158	549.00
IUUC-Ptr-091021	Pan troglodytes	99.11	3.00e-177	614.00
IUUC-Pan-091963	Papio anubis	98.45	3.00e-180	624.00
IUUC-Psi-093012	Pelodiscus sinensis	79.25	2.00e-142	498.00
IUUC-Pca-100164	Procavia capensis	92.02	5.00e-169	587.00
IUUC-Pva-102873	Pteropus vampyrus	94.01	2.00e-163	568.00
IUUC-Rno-104840	Rattus norvegicus	90.24	2.00e-147	515.00
IUUC-Sha-106551	Sarcophilus harrisii	85.56	6.00e-154	536.00
IUUC-Tsy-119236	Tarsius syrichta	88.69	7.00e-170	590.00
IUUC-Tni-120510	Tetraodon nigroviridis	64.38	2.00e-95	342.00
IUUC-Tbe-127947	Tupaia belangeri	85.59	4.00e-143	501.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence