iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lpe-051553

Ensembl Protein ID

LPERR03G14580.1

UniProt Accession

A0A0D9VTT6; A0A0D9VTT6_9ORYZ

Protein Name

Coatomer subunit alpha

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
LPERR03G14580	LPERR03G14580.1	LPERR03G14580.1
LPERR03G14580	LPERR03G14580.2	LPERR03G14580.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-39	133.2	50	86
UBD/Beta-Prp	3.00e-77	260.6	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 50   HDGPVRGVHFhaTQPLFVSGGDDYKIKVWNYKTHRCL 86
           99*********6449********************98 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           t +++++++++ + f+p +++++++  +g i+ wd+++g+ll ++ +h+++v+ v f+ +++++v+g++D+ ikvw+++t  c+ tl+gh d++
   Q: 3    TKFETKSNRVKGLSFHPRRPWILASLHSGVIQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDYKIKVWNYKTHRCLFTLHGHLDYI 96
           67889999************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......................... 166
           ++++f+ +  ++vs+s+d+tir+w++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                         
   Q: 97   RTVQFHNECPWIVSASDDQTIRIWNWQSRTCVA-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIsalrkksvspaddilrltqmntdlf 189
           *********************************.**************************************************7777777777 PP
   S: 167  ..ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
               + + + l+g h++ v++ sf+++ + +vsg++d++vk+w +  ++   v+tl+gh +nv++v f+ +++++vs s+D+siriWd ++++ 
   Q: 190  ggVDAVVKYVLEG-HDRGVNWASFHPTLPLIVSGADDRQVKIWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSDSEDKSIRIWDATKRTG 282
           6444444444466.********************************777668****************************************** PP
   S: 257  lktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           ++t+ +++++++  a+ +++ n l++g  ds   ++kl++++p
   Q: 283  IQTFRREHDRFWILAA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           ****************.6666655555.689999999988765 PP

Organism

Leersia perrieri

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPR RPWILASLHS GVIQMWDYRM GTLLDRFDEH DGPVRGVHFH 60
ATQPLFVSGG DDYKIKVWNY KTHRCLFTLH GHLDYIRTVQ FHNECPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGGAGTCT TTCCCTCGAC AATCTGGGCA TGCCCACACC AACGGTCCCG ATCTCGCTGC 60
GTCTCCAGAT CCAACGGCGG TCACGCCTCC CACACCTCAC CACCGCGTCC GAACCCAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cne-027053	Cryptococcus neoformans	50.24	0.00e+00	1161.00
IUUC-Psi-093044	Pelodiscus sinensis	54.13	0.00e+00	876.00
IUUC-Pte-104126	Pyrenophora teres	45.25	0.00e+00	1026.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	39.03	0.00e+00	701.00
IUUC-Tgu-117109	Taeniopygia guttata	43.05	2.00e-104	372.00
IUUC-Tca-121545	Theobroma cacao	78.16	0.00e+00	1956.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence