iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091478

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03094449

Gene Name

KLHL28

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000022780.5	ENSPTRT00000043040.5	ENSPTRP00000041466.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.40e-18	66.3	49	112
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-10	40.0	150	178

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D+il vg+++++ahk+vLa+ S++F+a+f+++l+e++ +++ve++ ++ ++++a++++ Ytg++
   Q: 49   CDIILRVGDVKIHAHKVVLASVSPYFKAMFTGNLSEKE-NSEVEFQCIDETALQAIVEYAYTGTV 112
           8***********************************97.************************87 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 4    clgilrfAdlydcpdLkdaaldfilkhFk 32
           c+gi rfA++y+c+dL++aa ++i+++F+
   Q: 150  CIGISRFAETYGCRDLYLAATKYICQNFE 178
           9***************************5 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MHFKCKYSYP ALYQMDHTSP TYMLANLTHL HSEQLLQGLN LLRQHHELCD IILRVGDVKI 60
HAHKVVLASV SPYFKAMFTG NLSEKENSEV EFQCIDETAL QAIVEYAYTG TVFISQDTVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACTTCA AATGCAAGTA TTCCTACCCT GCTCTGTACC AGGTGGGATT TCTCTTAAAT 60
ACTTTTTAAA GTCTTGGAAT AAATGAGTCA CATATGCCAA ACAGCTTTAT AAATAATGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030569--KLHL28
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001581	Ailuropoda melanoleuca	98.60	0.00e+00	1181.00
IUUC-Apl-003577	Anas platyrhynchos	92.25	0.00e+00	1079.00
IUUC-Aca-004320	Anolis carolinensis	86.18	0.00e+00	915.00
IUUC-Ame-011433	Astyanax mexicanus	84.06	0.00e+00	978.00
IUUC-Bta-012650	Bos taurus	98.77	0.00e+00	1182.00
IUUC-Cja-019878	Callithrix jacchus	98.78	0.00e+00	1183.00
IUUC-Cfa-020936	Canis familiaris	98.77	0.00e+00	1182.00
IUUC-Cpo-022212	Cavia porcellus	97.20	0.00e+00	1167.00
IUUC-Csa-023372	Chlorocebus sabaeus	99.12	0.00e+00	1182.00
IUUC-Cho-024885	Choloepus hoffmanni	97.32	5.00e-171	593.00
IUUC-Dno-029895	Dasypus novemcinctus	97.20	0.00e+00	1166.00
IUUC-Ete-032703	Echinops telfairi	97.54	0.00e+00	909.00
IUUC-Eca-034150	Equus caballus	98.60	0.00e+00	1179.00
IUUC-Eeu-035233	Erinaceus europaeus	96.15	0.00e+00	1155.00
IUUC-Fca-036445	Felis catus	98.42	0.00e+00	1177.00
IUUC-Fal-037156	Ficedula albicollis	82.14	0.00e+00	991.00
IUUC-Gmo-039158	Gadus morhua	84.06	0.00e+00	1007.00
IUUC-Gga-040855	Gallus gallus	91.08	0.00e+00	1112.00
IUUC-Gac-041294	Gasterosteus aculeatus	83.36	0.00e+00	998.00
IUUC-Ggo-045399	Gorilla gorilla	99.66	0.00e+00	1219.00
IUUC-Hsa-046199	Homo sapiens	99.66	0.00e+00	1219.00
IUUC-Itr-048859	Ictidomys tridecemlineatus	98.42	0.00e+00	1173.00
IUUC-Lch-049445	Latimeria chalumnae	87.70	0.00e+00	805.00
IUUC-Loc-052737	Lepisosteus oculatus	85.64	0.00e+00	1003.00
IUUC-Laf-054173	Loxodonta africana	97.90	0.00e+00	1168.00
IUUC-Mcc-055000	Macaca mulatta	98.97	0.00e+00	1213.00
IUUC-Meu-056028	Macropus eugenii	85.38	2.00e-142	498.00
IUUC-Mga-059609	Meleagris gallopavo	92.00	0.00e+00	1111.00
IUUC-Mmr-060842	Microcebus murinus	98.12	0.00e+00	1194.00
IUUC-Mdo-062776	Monodelphis domestica	92.31	0.00e+00	1080.00
IUUC-Mmu-063720	Mus musculus	96.67	0.00e+00	1164.00
IUUC-Mpu-066594	Mustela putorius furo	68.06	0.00e+00	728.00
IUUC-Mlu-067403	Myotis lucifugus	96.67	0.00e+00	1156.00
IUUC-Nle-069242	Nomascus leucogenys	98.95	0.00e+00	1181.00
IUUC-Opr-070942	Ochotona princeps	96.15	2.00e-177	614.00
IUUC-Ont-072586	Oreochromis niloticus	84.27	0.00e+00	1008.00
IUUC-Oan-073070	Ornithorhynchus anatinus	92.87	0.00e+00	1072.00
IUUC-Ocu-074536	Oryctolagus cuniculus	97.26	0.00e+00	1191.00
IUUC-Ola-086669	Oryzias latipes	70.64	0.00e+00	810.00
IUUC-Oga-088974	Otolemur garnettii	98.60	0.00e+00	1178.00
IUUC-Oar-089544	Ovis aries	98.43	0.00e+00	1182.00
IUUC-Pan-092653	Papio anubis	99.30	0.00e+00	1183.00
IUUC-Psi-094014	Pelodiscus sinensis	92.99	0.00e+00	1122.00
IUUC-Pfo-097316	Poecilia formosa	82.79	0.00e+00	1004.00
IUUC-Pab-098609	Pongo abelii	99.49	0.00e+00	1217.00
IUUC-Pva-102527	Pteropus vampyrus	96.17	1.00e-177	615.00
IUUC-Rno-105188	Rattus norvegicus	97.20	0.00e+00	1166.00
IUUC-Sha-106543	Sarcophilus harrisii	92.83	0.00e+00	1087.00
IUUC-Sar-113507	Sorex araneus	95.80	0.00e+00	1153.00
IUUC-Ssc-115803	Sus scrofa	98.42	0.00e+00	1176.00
IUUC-Tgu-116661	Taeniopygia guttata	81.38	0.00e+00	903.00
IUUC-Tru-118738	Takifugu rubripes	81.11	0.00e+00	974.00
IUUC-Tsy-119570	Tarsius syrichta	89.91	0.00e+00	1080.00
IUUC-Tni-120041	Tetraodon nigroviridis	82.69	0.00e+00	996.00
IUUC-Tbe-127655	Tupaia belangeri	91.43	0.00e+00	1056.00
IUUC-Ttr-129249	Tursiops truncatus	98.12	0.00e+00	1202.00
IUUC-Vpa-130034	Vicugna pacos	96.75	0.00e+00	1179.00
IUUC-Xtr-132964	Xenopus tropicalis	87.04	0.00e+00	1051.00
IUUC-Xma-133894	Xiphophorus maculatus	83.71	0.00e+00	998.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence