iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132964

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 28

Genbank Nucleotide ID

AAMC01105171

Gene Name

klhl28

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000003057.4	ENSXETT00000055693.3	ENSXETP00000055693.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.00e-18	66.7	35	98
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.50e-12	45.8	135	165

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D++l+vg+++++ahk+vLa+ S++F+a+f+++l+e++ ++ ve++ v+  +++a++++ Ytg++
   Q: 35   CDIVLQVGDVKIHAHKVVLASISPYFKAMFTGNLSEKE-NSQVEFQSVDEAALQAIIEYAYTGTV 98
           8***********************************97.************************87 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Nc+gi rfA++y+c++L++aa+++i+++F+
   Q: 135  GNCIGISRFAETYGCHELYLAANKYICQNFE 165
           5*****************************5 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MDQSSQSYML ANLTHLHSEQ LLQGLNLLRQ HHELCDIVLQ VGDVKIHAHK VVLASISPYF 60
KAMFTGNLSE KENSQVEFQS VDEAALQAII EYAYTGTVFI SQETVESLLP AANLLQIKLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCAGT CCTCCCAATC CTACATGCTT GCCAATTTAA CCCATCTTCA TTCGGAGCAA 60
CTTCTGCAGG GCTTAAATCT CCTCCGCCAG CACCACGAGC TCTGCGACAT TGTCCTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030569--KLHL28
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001581	Ailuropoda melanoleuca	87.57	0.00e+00	1061.00
IUUC-Apl-003577	Anas platyrhynchos	89.91	0.00e+00	1056.00
IUUC-Aca-004320	Anolis carolinensis	85.60	0.00e+00	911.00
IUUC-Ame-011433	Astyanax mexicanus	84.76	0.00e+00	986.00
IUUC-Bta-012650	Bos taurus	87.74	0.00e+00	1062.00
IUUC-Cja-019878	Callithrix jacchus	87.39	0.00e+00	1061.00
IUUC-Cfa-020936	Canis familiaris	87.92	0.00e+00	1062.00
IUUC-Cpo-022212	Cavia porcellus	87.04	0.00e+00	1051.00
IUUC-Csa-023372	Chlorocebus sabaeus	87.57	0.00e+00	1061.00
IUUC-Cho-024885	Choloepus hoffmanni	89.97	6.00e-159	553.00
IUUC-Dno-029895	Dasypus novemcinctus	87.57	0.00e+00	1060.00
IUUC-Ete-032703	Echinops telfairi	85.91	0.00e+00	815.00
IUUC-Eca-034150	Equus caballus	87.92	0.00e+00	1065.00
IUUC-Eeu-035233	Erinaceus europaeus	86.16	0.00e+00	1042.00
IUUC-Fca-036445	Felis catus	87.74	0.00e+00	1058.00
IUUC-Fal-037156	Ficedula albicollis	80.74	0.00e+00	972.00
IUUC-Gmo-039158	Gadus morhua	84.59	0.00e+00	1008.00
IUUC-Gga-040855	Gallus gallus	90.19	0.00e+00	1086.00
IUUC-Gac-041294	Gasterosteus aculeatus	83.54	0.00e+00	999.00
IUUC-Ggo-045399	Gorilla gorilla	87.39	0.00e+00	1060.00
IUUC-Hsa-046199	Homo sapiens	87.39	0.00e+00	1060.00
IUUC-Itr-048859	Ictidomys tridecemlineatus	87.39	0.00e+00	1060.00
IUUC-Lch-049445	Latimeria chalumnae	89.71	0.00e+00	823.00
IUUC-Loc-052737	Lepisosteus oculatus	85.81	0.00e+00	1010.00
IUUC-Laf-054173	Loxodonta africana	86.71	0.00e+00	1049.00
IUUC-Mcc-055000	Macaca mulatta	87.39	0.00e+00	1059.00
IUUC-Meu-056028	Macropus eugenii	84.62	1.00e-141	496.00
IUUC-Mga-059609	Meleagris gallopavo	90.03	0.00e+00	1083.00
IUUC-Mmr-060842	Microcebus murinus	87.39	0.00e+00	1059.00
IUUC-Mdo-062776	Monodelphis domestica	89.67	0.00e+00	1055.00
IUUC-Mmu-063720	Mus musculus	86.51	0.00e+00	1053.00
IUUC-Mpu-066594	Mustela putorius furo	76.88	2.00e-146	512.00
IUUC-Mlu-067403	Myotis lucifugus	86.34	0.00e+00	1041.00
IUUC-Nle-069242	Nomascus leucogenys	86.87	0.00e+00	1054.00
IUUC-Opr-070942	Ochotona princeps	89.30	6.00e-160	556.00
IUUC-Ont-072586	Oreochromis niloticus	84.76	0.00e+00	1009.00
IUUC-Oan-073070	Ornithorhynchus anatinus	90.13	0.00e+00	1045.00
IUUC-Ocu-074536	Oryctolagus cuniculus	86.87	0.00e+00	1051.00
IUUC-Ola-086669	Oryzias latipes	69.78	0.00e+00	799.00
IUUC-Oga-088974	Otolemur garnettii	87.22	0.00e+00	1059.00
IUUC-Oar-089544	Ovis aries	87.57	0.00e+00	1063.00
IUUC-Ptr-091478	Pan troglodytes	87.04	0.00e+00	1051.00
IUUC-Pan-092653	Papio anubis	87.39	0.00e+00	1060.00
IUUC-Psi-094014	Pelodiscus sinensis	91.07	0.00e+00	1097.00
IUUC-Pfo-097316	Poecilia formosa	84.41	0.00e+00	1003.00
IUUC-Pab-098609	Pongo abelii	87.22	0.00e+00	1058.00
IUUC-Pva-102527	Pteropus vampyrus	89.30	2.00e-159	555.00
IUUC-Rno-105188	Rattus norvegicus	87.04	0.00e+00	1056.00
IUUC-Sha-106543	Sarcophilus harrisii	89.67	0.00e+00	1056.00
IUUC-Sar-113507	Sorex araneus	86.34	0.00e+00	1048.00
IUUC-Ssc-115803	Sus scrofa	87.57	0.00e+00	1060.00
IUUC-Tgu-116661	Taeniopygia guttata	80.45	0.00e+00	892.00
IUUC-Tru-118738	Takifugu rubripes	82.09	0.00e+00	981.00
IUUC-Tsy-119570	Tarsius syrichta	80.74	0.00e+00	951.00
IUUC-Tni-120041	Tetraodon nigroviridis	83.54	0.00e+00	1001.00
IUUC-Tre-122227	Trichoderma reesei	31.25	9.00e-07	46.60
IUUC-Tbe-127655	Tupaia belangeri	80.59	0.00e+00	942.00
IUUC-Ttr-129249	Tursiops truncatus	87.74	0.00e+00	1061.00
IUUC-Vpa-130034	Vicugna pacos	87.22	0.00e+00	1058.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence