iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051933

Ensembl Protein ID

ENSLOCP00000011953.1

UniProt Accession

W5MU94; W5MU94_LEPOC

Genbank Protein ID

ENSLOCP00000011953

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AHAT01000054

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000009782.1	ENSLOCT00000011974.1	ENSLOCP00000011953.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.30e-12	46.8	72	129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 72   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 129
           67899************************.*********98..788899*********997 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MLLRTLPPSS SFEEEWSRLT GHLSQSSEDV YQTSLSEALH RPYGLEPDSS ALTEAVRWSS 60
KENLLGATES DPNLFVALYD FVASGDNTLS ITKGEKLRVL GYNQNGEWSE VRSKNGQGWV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGGTTTCTA TAGAGAAGAG CCTCTGCCTT ATTAGGCGTG GGCCAGAAGG AAATATTCAG 60
ACCCCCTTAA ACCACACCAG GACTGGCGAG GTGCCCGGGC CTTTGAGCTG CAGCACAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	71.18	0.00e+00	1438.00
IUUC-Apl-003389	Anas platyrhynchos	70.27	0.00e+00	1394.00
IUUC-Ame-010629	Astyanax mexicanus	66.04	0.00e+00	1281.00
IUUC-Bta-013370	Bos taurus	69.38	0.00e+00	1424.00
IUUC-Cja-018894	Callithrix jacchus	71.05	0.00e+00	1438.00
IUUC-Cfa-020398	Canis familiaris	84.41	0.00e+00	1103.00
IUUC-Cpo-022367	Cavia porcellus	70.43	0.00e+00	1410.00
IUUC-Csa-023386	Chlorocebus sabaeus	71.07	0.00e+00	1443.00
IUUC-Cho-024714	Choloepus hoffmanni	80.87	0.00e+00	1194.00
IUUC-Dre-027741	Danio rerio	78.44	0.00e+00	1604.00
IUUC-Dno-029246	Dasypus novemcinctus	70.73	0.00e+00	1416.00
IUUC-Dor-030416	Dipodomys ordii	65.24	0.00e+00	1275.00
IUUC-Ete-032899	Echinops telfairi	94.72	8.00e-131	461.00
IUUC-Eca-033387	Equus caballus	70.06	0.00e+00	1432.00
IUUC-Eeu-035058	Erinaceus europaeus	65.71	0.00e+00	1339.00
IUUC-Fca-036578	Felis catus	67.78	0.00e+00	1302.00
IUUC-Fal-037491	Ficedula albicollis	71.80	0.00e+00	1479.00
IUUC-Gmo-038509	Gadus morhua	77.38	0.00e+00	1271.00
IUUC-Gga-040638	Gallus gallus	71.21	0.00e+00	1437.00
IUUC-Gac-042550	Gasterosteus aculeatus	75.58	0.00e+00	1494.00
IUUC-Ggo-044487	Gorilla gorilla	69.56	0.00e+00	1435.00
IUUC-Hsa-046636	Homo sapiens	69.81	0.00e+00	1435.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	70.03	0.00e+00	1447.00
IUUC-Lch-049530	Latimeria chalumnae	74.02	0.00e+00	1484.00
IUUC-Laf-053802	Loxodonta africana	69.84	0.00e+00	1469.00
IUUC-Mcc-054836	Macaca mulatta	70.25	0.00e+00	1442.00
IUUC-Mga-059277	Meleagris gallopavo	71.65	0.00e+00	1451.00
IUUC-Mmr-061206	Microcebus murinus	69.26	0.00e+00	1380.00
IUUC-Mdo-062281	Monodelphis domestica	84.53	0.00e+00	1100.00
IUUC-Mmu-063847	Mus musculus	70.15	0.00e+00	1407.00
IUUC-Mpu-066309	Mustela putorius furo	85.07	0.00e+00	1102.00
IUUC-Mlu-068070	Myotis lucifugus	70.69	0.00e+00	1436.00
IUUC-Nle-070062	Nomascus leucogenys	85.23	0.00e+00	1103.00
IUUC-Ont-072440	Oreochromis niloticus	74.55	0.00e+00	1496.00
IUUC-Oan-073526	Ornithorhynchus anatinus	75.30	0.00e+00	1309.00
IUUC-Ocu-074051	Oryctolagus cuniculus	70.68	0.00e+00	1407.00
IUUC-Oba-075747	Oryza barthii	33.84	1.00e-21	99.40
IUUC-Ola-086752	Oryzias latipes	97.19	0.00e+00	923.00
IUUC-Oga-088767	Otolemur garnettii	65.36	0.00e+00	1254.00
IUUC-Oar-089800	Ovis aries	70.62	0.00e+00	1426.00
IUUC-Ptr-090857	Pan troglodytes	85.40	0.00e+00	1106.00
IUUC-Pan-092279	Papio anubis	70.79	0.00e+00	1439.00
IUUC-Psi-093573	Pelodiscus sinensis	71.34	0.00e+00	1410.00
IUUC-Pma-094420	Petromyzon marinus	74.82	0.00e+00	858.00
IUUC-Pfo-096543	Poecilia formosa	74.67	0.00e+00	1413.00
IUUC-Pab-097949	Pongo abelii	69.72	0.00e+00	1405.00
IUUC-Pca-100370	Procavia capensis	64.59	0.00e+00	977.00
IUUC-Pva-103220	Pteropus vampyrus	63.10	0.00e+00	1223.00
IUUC-Rno-105924	Rattus norvegicus	70.17	0.00e+00	1405.00
IUUC-Sha-107114	Sarcophilus harrisii	76.92	0.00e+00	1202.00
IUUC-Sit-110219	Setaria italica	30.50	2.00e-20	94.70
IUUC-Sbi-114480	Sorghum bicolor	32.42	1.00e-23	105.00
IUUC-Ssc-115968	Sus scrofa	69.90	0.00e+00	1436.00
IUUC-Tgu-117301	Taeniopygia guttata	71.94	0.00e+00	1456.00
IUUC-Tru-118410	Takifugu rubripes	76.47	0.00e+00	1558.00
IUUC-Tni-119991	Tetraodon nigroviridis	76.31	0.00e+00	1563.00
IUUC-Tca-121389	Theobroma cacao	34.02	4.00e-24	106.00
IUUC-Tbe-127362	Tupaia belangeri	78.30	0.00e+00	1222.00
IUUC-Ttr-129291	Tursiops truncatus	70.66	0.00e+00	1439.00
IUUC-Vpa-130800	Vicugna pacos	77.18	0.00e+00	1253.00
IUUC-Xtr-132965	Xenopus tropicalis	71.66	0.00e+00	1173.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence