iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000006614.1	ENSONIT00000008360.1	ENSONIP00000008355.1
ENSONIG00000006614.1	ENSONIT00000008361.1	ENSONIP00000008356.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-16	59.7	1161	1194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++++t++   d t+ l+sG+ Dg i +WD+ tg
   Q: 1161 GHSGGITAIYI-DqTMvLASGGQDGAICLWDVLTG 1194
           8********88.446648*************9887 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MPLSSFTTSC LSTCERDAKC AFWVWCSPSV TTVQSVKDWG RKRVQAREIN WSPIGRSLDA 60
PRRTVLGRPV LPNGRELTKP TKMTLREQLR EKISAAFYRH GLLCASYPVP IILFTSASIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGAAGAGTG CAGGTGCATC TCTGAGGCGA AATTGGTCAC TATTACCATG GAAGTGTACT 60
AATAATAATA ATAATAATAA GAAGAAGAAG AAGAAGAAGA AGAAGAAGGA GAAGAAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR027295--Quinoprotein_ADH-like_fam
IPR011047--Quinoprotein_ADH-like_supfam
IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0019915--P:lipid storage
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	72.85	0.00e+00	825.00
IUUC-Apl-003294	Anas platyrhynchos	68.25	0.00e+00	1533.00
IUUC-Aca-004424	Anolis carolinensis	63.15	0.00e+00	1352.00
IUUC-Bta-013478	Bos taurus	67.23	0.00e+00	1465.00
IUUC-Cel-018160	Caenorhabditis elegans	28.60	2.00e-64	241.00
IUUC-Cja-019123	Callithrix jacchus	64.74	0.00e+00	1394.00
IUUC-Cfa-021082	Canis familiaris	67.23	0.00e+00	1436.00
IUUC-Cpo-022477	Cavia porcellus	67.14	0.00e+00	1427.00
IUUC-Csa-023176	Chlorocebus sabaeus	65.97	0.00e+00	1441.00
IUUC-Cin-025490	Ciona intestinalis	39.38	2.00e-91	330.00
IUUC-Csv-026115	Ciona savignyi	38.58	2.00e-132	467.00
IUUC-Dre-028008	Danio rerio	83.06	0.00e+00	1891.00
IUUC-Dno-028887	Dasypus novemcinctus	71.41	0.00e+00	886.00
IUUC-Dor-030467	Dipodomys ordii	76.01	0.00e+00	689.00
IUUC-Dme-032087	Drosophila melanogaster	31.24	5.00e-108	386.00
IUUC-Ete-032372	Echinops telfairi	57.13	0.00e+00	1169.00
IUUC-Eca-033896	Equus caballus	67.23	0.00e+00	1519.00
IUUC-Eeu-035099	Erinaceus europaeus	65.84	0.00e+00	862.00
IUUC-Fca-035616	Felis catus	72.42	0.00e+00	836.00
IUUC-Fal-037231	Ficedula albicollis	67.85	0.00e+00	1469.00
IUUC-Gmo-039439	Gadus morhua	76.48	0.00e+00	1093.00
IUUC-Gac-041516	Gasterosteus aculeatus	87.07	0.00e+00	1972.00
IUUC-Hsa-046674	Homo sapiens	67.08	0.00e+00	1487.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	66.72	0.00e+00	1501.00
IUUC-Lch-049689	Latimeria chalumnae	65.13	0.00e+00	1497.00
IUUC-Loc-052417	Lepisosteus oculatus	68.46	0.00e+00	640.00
IUUC-Laf-053795	Loxodonta africana	70.97	0.00e+00	1013.00
IUUC-Mcc-055502	Macaca mulatta	66.97	0.00e+00	1487.00
IUUC-Mga-059805	Meleagris gallopavo	68.84	0.00e+00	1528.00
IUUC-Mmr-060997	Microcebus murinus	66.44	0.00e+00	1504.00
IUUC-Mdo-062940	Monodelphis domestica	66.51	0.00e+00	1488.00
IUUC-Mmu-063255	Mus musculus	66.85	0.00e+00	1473.00
IUUC-Mpu-066158	Mustela putorius furo	67.85	0.00e+00	1490.00
IUUC-Mlu-067201	Myotis lucifugus	65.51	0.00e+00	1437.00
IUUC-Nle-069145	Nomascus leucogenys	72.37	0.00e+00	975.00
IUUC-Opr-070797	Ochotona princeps	63.19	0.00e+00	1350.00
IUUC-Ocu-074598	Oryctolagus cuniculus	66.87	0.00e+00	1477.00
IUUC-Ola-086650	Oryzias latipes	97.30	6.00e-124	436.00
IUUC-Oar-089287	Ovis aries	67.13	0.00e+00	827.00
IUUC-Pan-092004	Papio anubis	67.19	0.00e+00	1459.00
IUUC-Psi-093028	Pelodiscus sinensis	64.48	0.00e+00	1323.00
IUUC-Pma-094145	Petromyzon marinus	49.49	0.00e+00	1116.00
IUUC-Pfo-096320	Poecilia formosa	88.29	0.00e+00	2070.00
IUUC-Pab-097862	Pongo abelii	67.13	0.00e+00	1495.00
IUUC-Pca-100862	Procavia capensis	59.31	0.00e+00	1088.00
IUUC-Pva-103050	Pteropus vampyrus	72.00	0.00e+00	960.00
IUUC-Rno-105852	Rattus norvegicus	67.05	0.00e+00	1476.00
IUUC-Sha-107312	Sarcophilus harrisii	70.33	0.00e+00	1051.00
IUUC-Sar-113311	Sorex araneus	57.97	5.00e-159	555.00
IUUC-Ssc-116356	Sus scrofa	66.98	0.00e+00	1491.00
IUUC-Tgu-116896	Taeniopygia guttata	62.42	5.00e-84	306.00
IUUC-Tru-118197	Takifugu rubripes	87.97	0.00e+00	2000.00
IUUC-Tni-119823	Tetraodon nigroviridis	81.17	0.00e+00	1872.00
IUUC-Ttr-129164	Tursiops truncatus	67.28	0.00e+00	1477.00
IUUC-Xtr-132819	Xenopus tropicalis	64.39	0.00e+00	1509.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence