iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053997

UUCD1 version

UUC-LoA-00727

Ensembl Protein ID

ENSLAFP00000019664.1

UniProt Accession

G3TVQ6; G3TVQ6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

WDR59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000023216.2	ENSLAFT00000021767.2	ENSLAFP00000016520.2
ENSLAFG00000023216.2	ENSLAFT00000036648.1	ENSLAFP00000019664.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-19	68.1	190	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           H +++++l++ +d  ++l+++s D+++k WD+r+ 
   Q: 190  HLSKIHGLDWhPDseHILATSSQDNSVKFWDYRQP 224
           99*********6665778*************9876 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAARWSSENV VVEFRDSQAT AMSVDCLGQH AVLSGRRFLY IVNLDAPFEG HRKISRQSKW 60
DIGAVQWNPH DSFAHYLAAS SNQRVDLYKW KDGSGEVGTT LQGHTRVISD LDWAVFDPDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGCGA GATGGAGCAG CGAAAATGTG GTGGTGGAGT TCCGCGATTC TCAGGTGAGC 60
TGGGGCCCAA ATGAAGCTTC TGGGCATGCG CCGTGGTTAC CCTCCCCCAC GCTGTTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00591--RWD
SM00320--WD40

Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002149	Ailuropoda melanoleuca	94.96	0.00e+00	1913.00
IUUC-Apl-004021	Anas platyrhynchos	87.12	0.00e+00	1686.00
IUUC-Aca-004977	Anolis carolinensis	86.42	0.00e+00	1750.00
IUUC-Ago-007961	Ashbya gossypii	24.72	7.00e-61	229.00
IUUC-Acl-008161	Aspergillus clavatus	28.84	2.00e-57	218.00
IUUC-Afl-008686	Aspergillus flavus	28.31	2.00e-58	221.00
IUUC-Afu-008932	Aspergillus fumigatus	28.20	2.00e-57	218.00
IUUC-Ani-009493	Aspergillus nidulans	34.35	4.00e-54	207.00
IUUC-Ang-009876	Aspergillus niger	28.63	9.00e-59	222.00
IUUC-Aor-009926	Aspergillus oryzae	28.31	2.00e-58	221.00
IUUC-Ate-010274	Aspergillus terreus	27.59	1.00e-55	212.00
IUUC-Ame-011297	Astyanax mexicanus	71.36	0.00e+00	1439.00
IUUC-Bgr-012173	Blumeria graminis	31.48	2.00e-44	174.00
IUUC-Bta-013261	Bos taurus	94.86	0.00e+00	1922.00
IUUC-Bci-013971	Botrytis cinerea	32.84	1.00e-46	182.00
IUUC-Cja-019167	Callithrix jacchus	94.36	0.00e+00	1907.00
IUUC-Cfa-020287	Canis familiaris	94.36	0.00e+00	1901.00
IUUC-Cpo-022510	Cavia porcellus	92.04	0.00e+00	1806.00
IUUC-Csa-023474	Chlorocebus sabaeus	97.99	0.00e+00	2000.00
IUUC-Cho-024634	Choloepus hoffmanni	93.14	0.00e+00	789.00
IUUC-Cin-025642	Ciona intestinalis	32.42	1.00e-132	467.00
IUUC-Csv-025848	Ciona savignyi	45.15	6.00e-55	206.00
IUUC-Cgl-026531	Colletotrichum gloeosporioides	32.80	1.00e-44	176.00
IUUC-Cne-027088	Cryptococcus neoformans	32.32	6.00e-44	172.00
IUUC-Dre-028753	Danio rerio	70.31	0.00e+00	1384.00
IUUC-Dno-029733	Dasypus novemcinctus	93.25	0.00e+00	1873.00
IUUC-Dor-030781	Dipodomys ordii	93.58	0.00e+00	978.00
IUUC-Dme-031803	Drosophila melanogaster	33.66	1.00e-147	517.00
IUUC-Ete-032622	Echinops telfairi	86.30	0.00e+00	1702.00
IUUC-Eca-033344	Equus caballus	95.57	0.00e+00	1917.00
IUUC-Eeu-034523	Erinaceus europaeus	84.82	0.00e+00	1652.00
IUUC-Fca-035650	Felis catus	95.37	0.00e+00	1924.00
IUUC-Fal-037404	Ficedula albicollis	86.89	0.00e+00	1725.00
IUUC-Fox-037955	Fusarium oxysporum	33.81	4.00e-43	170.00
IUUC-Fso-038289	Fusarium solani	33.54	4.00e-47	184.00
IUUC-Gmo-038547	Gadus morhua	68.67	0.00e+00	1421.00
IUUC-Ggr-039858	Gaeumannomyces graminis	36.10	3.00e-43	171.00
IUUC-Gga-041030	Gallus gallus	87.11	0.00e+00	1732.00
IUUC-Gac-042581	Gasterosteus aculeatus	72.10	0.00e+00	1469.00
IUUC-Ggo-044641	Gorilla gorilla	95.57	0.00e+00	1932.00
IUUC-Hsa-046134	Homo sapiens	95.77	0.00e+00	1934.00
IUUC-Itr-048551	Ictidomys tridecemlineatus	96.48	0.00e+00	750.00
IUUC-Kpa-049091	Komagataella pastoris	32.93	2.00e-46	181.00
IUUC-Lch-050288	Latimeria chalumnae	73.65	0.00e+00	1457.00
IUUC-Loc-052802	Lepisosteus oculatus	75.53	0.00e+00	1536.00
IUUC-Lma-053296	Leptosphaeria maculans	32.92	8.00e-49	189.00
IUUC-Mcc-055855	Macaca mulatta	95.67	0.00e+00	1918.00
IUUC-Meu-056898	Macropus eugenii	90.84	0.00e+00	731.00
IUUC-Mor-056913	Magnaporthe oryzae	34.98	1.00e-42	169.00
IUUC-Mpo-057612	Magnaporthe poae	36.46	1.00e-43	172.00
IUUC-Mla-059097	Melampsora laricipopulina	30.67	2.00e-47	185.00
IUUC-Mga-059218	Meleagris gallopavo	87.09	0.00e+00	1697.00
IUUC-Mvi-060251	Microbotryum violaceum	31.60	7.00e-47	182.00
IUUC-Mmr-061093	Microcebus murinus	91.94	0.00e+00	1843.00
IUUC-Mdo-062757	Monodelphis domestica	91.22	0.00e+00	1821.00
IUUC-Mmu-063839	Mus musculus	96.07	0.00e+00	1974.00
IUUC-Mpu-065977	Mustela putorius furo	94.96	0.00e+00	1915.00
IUUC-Mlu-067460	Myotis lucifugus	93.09	0.00e+00	1909.00
IUUC-Nfi-068250	Neosartorya fischeri	28.10	2.00e-57	218.00
IUUC-Ncr-068710	Neurospora crassa	32.45	2.00e-45	178.00
IUUC-Nle-070011	Nomascus leucogenys	95.47	0.00e+00	1926.00
IUUC-Opr-070731	Ochotona princeps	92.60	0.00e+00	1101.00
IUUC-Ont-072165	Oreochromis niloticus	69.52	0.00e+00	1415.00
IUUC-Oan-072887	Ornithorhynchus anatinus	93.81	0.00e+00	1910.00
IUUC-Ocu-073926	Oryctolagus cuniculus	96.95	0.00e+00	1812.00
IUUC-Ola-087111	Oryzias latipes	68.37	0.00e+00	1392.00
IUUC-Oga-088850	Otolemur garnettii	95.17	0.00e+00	1919.00
IUUC-Oar-090291	Ovis aries	94.56	0.00e+00	1914.00
IUUC-Ptr-091044	Pan troglodytes	95.47	0.00e+00	1921.00
IUUC-Pan-092374	Papio anubis	97.78	0.00e+00	1995.00
IUUC-Psi-093170	Pelodiscus sinensis	54.97	0.00e+00	964.00
IUUC-Pma-094544	Petromyzon marinus	66.22	2.00e-169	588.00
IUUC-Pno-095068	Phaeosphaeria nodorum	30.56	1.00e-44	175.00
IUUC-Pfo-096480	Poecilia formosa	69.46	0.00e+00	1372.00
IUUC-Pab-098134	Pongo abelii	94.34	0.00e+00	1886.00
IUUC-Pca-100763	Procavia capensis	73.14	0.00e+00	991.00
IUUC-Pva-102544	Pteropus vampyrus	93.76	0.00e+00	1904.00
IUUC-Pgr-103257	Puccinia graminis	32.33	2.00e-50	194.00
IUUC-Ptt-103942	Puccinia triticina	31.55	5.00e-46	179.00
IUUC-Pte-104065	Pyrenophora teres	32.20	3.00e-46	181.00
IUUC-Rno-105468	Rattus norvegicus	94.53	0.00e+00	1800.00
IUUC-Sce-106356	Saccharomyces cerevisiae	28.52	5.00e-58	219.00
IUUC-Sha-106662	Sarcophilus harrisii	93.15	0.00e+00	1848.00
IUUC-Sja-107973	Schizosaccharomyces japonicus	27.48	3.00e-72	267.00
IUUC-Spo-108265	Schizosaccharomyces pombe	24.91	9.00e-72	265.00
IUUC-Ssl-108662	Sclerotinia sclerotiorum	33.43	5.00e-46	180.00
IUUC-Sar-113525	Sorex araneus	89.97	0.00e+00	1070.00
IUUC-Sre-115163	Sporisorium reilianum	37.05	2.00e-40	161.00
IUUC-Ssc-115381	Sus scrofa	93.06	0.00e+00	1038.00
IUUC-Tgu-116525	Taeniopygia guttata	83.60	0.00e+00	1663.00
IUUC-Tru-118432	Takifugu rubripes	70.50	0.00e+00	1449.00
IUUC-Tsy-119306	Tarsius syrichta	82.46	0.00e+00	944.00
IUUC-Tni-120757	Tetraodon nigroviridis	69.99	0.00e+00	1410.00
IUUC-Tre-122187	Trichoderma reesei	35.03	4.00e-48	187.00
IUUC-Tvi-122367	Trichoderma virens	35.35	1.00e-47	186.00
IUUC-Tme-126986	Tuber melanosporum	29.51	6.00e-56	213.00
IUUC-Tbe-127800	Tupaia belangeri	80.20	0.00e+00	1368.00
IUUC-Ttr-129154	Tursiops truncatus	90.94	0.00e+00	1030.00
IUUC-Uma-129366	Ustilago maydis	35.97	2.00e-39	158.00
IUUC-Vda-129827	Verticillium dahliae	33.86	1.00e-47	186.00
IUUC-Vpa-130493	Vicugna pacos	94.87	0.00e+00	1865.00
IUUC-Xtr-131941	Xenopus tropicalis	79.48	0.00e+00	1592.00
IUUC-Xma-133903	Xiphophorus maculatus	68.68	0.00e+00	1397.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence