iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118472

Ensembl Protein ID

ENSTRUP00000019242.1

UniProt Accession

H2T3K4; H2T3K4_TAKRU

Protein Name

Uncharacterized protein

Gene Name

znf106a; znf106

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000007738.1	ENSTRUT00000019320.1	ENSTRUP00000019242.1
ENSTRUG00000007738.1	ENSTRUT00000019321.1	ENSTRUP00000019243.1
ENSTRUG00000007738.1	ENSTRUT00000019322.1	ENSTRUP00000019244.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.00e-19	68.6	1363	1404
UBD/Beta-Prp	3.10e-47	162.4	1321	1514

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd..tllvsGsdDgtikvWDlrtgvllk 37
           gH+++v+cl     ++  ++l sGs D ti++++l+t  l++
   Q: 1363 GHSSKVSCLLVsaaPSlhHRLYSGSSDQTIRCYSLKTRELEQ 1404
           8*******955999666688***************9987776 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee 131
           ++gh+++v+a+++++   +l t+s Drt++ +dl t kcv +++gh+++v +l +s+  s  ++l sGs+d+tir++ l+t++  + 
   Q: 1321 FEGHQEAVNAMQIHNG--LLYTCSGDRTVRAFDLVTHKCVGVFEGHSSKVSCLLVSAapSLhHRLYSGSSDQTIRCYSLKTRELEQ- 1404
           689*************..9********************************96655555666********************9998. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwdlqtgecvr 216
            +s  d   +++++h+  + l +G +++tv  ++lkt++ ++ ++    ++v +l+ +++g  + l+ gs+d+t+ + d ++g  +r
   Q: 1405 QFSLPD---RVLCLHSRWKTLYAGLANGTVVTFNLKTNRQVEVFECHGPRAVSCLASTQEGarRILLVGSYDSTISVRDAKNGLLLR 1488
           444433...566667766**************************9977899*****999999999********************** PP
   S: 217  tlnghtdnvksvrfspnderlvsgssDg 244
           tl+gh++ v+++++   ++++ sgssD+
   Q: 1489 TLEGHSKSVLCMNVV--NDLVFSGSSDQ 1514
           ***************..99******996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MERNRKCILC ETVHASKQEM DEHMRSMLHH RELEKLKGRD CGHQCRVCHV TVASLTDYAG 60
HISSPTHKQN VEAADRKPAG KGRDEDYFDQ VLVDLIEKRK EQQPSLQPKK SSKSSQRNEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAGAA ACAGGAAGTG CATCCTCTGT GAAACAGTCC ATGCCTCCAA GCAGGTAACC 60
CTCAGAACTT TGTATTTATC CCCCAGAGAA GCTCCGGGTT CGTTAGCAGT GAAACTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR003604--Matrin/U1-like-C_Znf_C2H2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013087--Znf_C2H2_type

PROSITE

PS50294--WD_REPEATS_REGION
PS00028--ZINC_FINGER_C2H2_1

Pfam

PF00400--WD40

SMART

SM00320--WD40
SM00355--ZnF_C2H2
SM00451--ZnF_U1

Gene Ontology

GO:0005829--C:cytosol
GO:0016020--C:membrane
GO:0003676--F:nucleic acid binding
GO:0017124--F:SH3 domain binding
GO:0008270--F:zinc ion binding
GO:0008286--P:insulin receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001928	Ailuropoda melanoleuca	57.98	2.00e-171	597.00
IUUC-Apl-003674	Anas platyrhynchos	42.74	0.00e+00	735.00
IUUC-Aca-005018	Anolis carolinensis	54.24	3.00e-161	563.00
IUUC-Ame-011431	Astyanax mexicanus	50.82	0.00e+00	914.00
IUUC-Bta-013436	Bos taurus	46.66	0.00e+00	708.00
IUUC-Cfa-020278	Canis familiaris	37.06	2.00e-73	271.00
IUUC-Cpo-022278	Cavia porcellus	54.39	2.00e-169	590.00
IUUC-Csa-023115	Chlorocebus sabaeus	55.34	8.00e-173	602.00
IUUC-Cho-024829	Choloepus hoffmanni	66.93	4.00e-105	377.00
IUUC-Dre-028112	Danio rerio	59.56	0.00e+00	647.00
IUUC-Dno-029127	Dasypus novemcinctus	58.77	6.00e-172	599.00
IUUC-Dor-030367	Dipodomys ordii	53.57	4.00e-150	526.00
IUUC-Ete-032500	Echinops telfairi	66.98	7.00e-139	489.00
IUUC-Eca-034319	Equus caballus	58.40	8.00e-171	595.00
IUUC-Eeu-034754	Erinaceus europaeus	54.16	5.00e-128	452.00
IUUC-Fca-036181	Felis catus	46.93	0.00e+00	683.00
IUUC-Fal-036865	Ficedula albicollis	62.99	3.00e-156	547.00
IUUC-Gmo-039227	Gadus morhua	66.22	2.00e-179	622.00
IUUC-Gga-041178	Gallus gallus	43.07	0.00e+00	659.00
IUUC-Gac-042209	Gasterosteus aculeatus	60.44	0.00e+00	855.00
IUUC-Ggo-044636	Gorilla gorilla	46.33	0.00e+00	692.00
IUUC-Hsa-045949	Homo sapiens	46.70	0.00e+00	701.00
IUUC-Itr-048628	Ictidomys tridecemlineatus	56.02	2.00e-174	607.00
IUUC-Lch-049753	Latimeria chalumnae	43.26	1.00e-171	597.00
IUUC-Loc-052333	Lepisosteus oculatus	54.78	4.00e-159	556.00
IUUC-Laf-053530	Loxodonta africana	57.26	2.00e-167	584.00
IUUC-Mcc-054664	Macaca mulatta	47.03	0.00e+00	697.00
IUUC-Meu-056609	Macropus eugenii	48.39	5.00e-137	483.00
IUUC-Mga-059632	Meleagris gallopavo	44.94	0.00e+00	650.00
IUUC-Mmr-060742	Microcebus murinus	58.99	6.00e-172	599.00
IUUC-Mdo-061831	Monodelphis domestica	45.26	0.00e+00	781.00
IUUC-Mmu-064055	Mus musculus	58.65	3.00e-168	586.00
IUUC-Mpu-066458	Mustela putorius furo	58.77	6.00e-168	585.00
IUUC-Mlu-067767	Myotis lucifugus	55.95	3.00e-175	610.00
IUUC-Nle-069728	Nomascus leucogenys	46.35	0.00e+00	699.00
IUUC-Opr-070914	Ochotona princeps	53.93	2.00e-169	591.00
IUUC-Ont-072353	Oreochromis niloticus	58.10	0.00e+00	1677.00
IUUC-Ocu-073827	Oryctolagus cuniculus	45.67	0.00e+00	684.00
IUUC-Oga-088664	Otolemur garnettii	47.23	0.00e+00	694.00
IUUC-Oar-090256	Ovis aries	36.45	9.00e-65	243.00
IUUC-Ptr-090884	Pan troglodytes	47.03	0.00e+00	699.00
IUUC-Pan-091779	Papio anubis	55.34	1.00e-172	601.00
IUUC-Psi-093267	Pelodiscus sinensis	69.26	1.00e-123	435.00
IUUC-Pma-094414	Petromyzon marinus	46.55	7.00e-39	155.00
IUUC-Pfo-097009	Poecilia formosa	59.28	0.00e+00	1056.00
IUUC-Pca-100820	Procavia capensis	54.89	3.00e-81	297.00
IUUC-Pva-103044	Pteropus vampyrus	68.39	4.00e-163	569.00
IUUC-Rno-105960	Rattus norvegicus	54.36	2.00e-167	584.00
IUUC-Sar-113018	Sorex araneus	49.91	5.00e-147	516.00
IUUC-Ssc-115278	Sus scrofa	46.85	0.00e+00	702.00
IUUC-Tgu-117231	Taeniopygia guttata	62.20	6.00e-155	542.00
IUUC-Tsy-118877	Tarsius syrichta	68.24	9.00e-146	511.00
IUUC-Tni-119881	Tetraodon nigroviridis	67.99	0.00e+00	1943.00
IUUC-Tbe-127499	Tupaia belangeri	66.26	2.00e-133	471.00
IUUC-Ttr-128962	Tursiops truncatus	57.93	6.00e-165	575.00
IUUC-Vpa-130089	Vicugna pacos	64.53	8.00e-70	259.00
IUUC-Xtr-132940	Xenopus tropicalis	63.05	4.00e-158	553.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence