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Tag Content
UUCD2 ID IUUC-Cpo-021453
UUCD1 version UUC-CaP-00040
Ensembl Protein ID ENSCPOP00000000960.2
UniProt Accession H0UVD2; H0UVD2_CAVPO
Genbank Protein ID ENSCPOP00000000960
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAKN02024801
Gene Name CBL
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000001063.3 ENSCPOT00000001074.2 ENSCPOP00000000960.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 1.90e-07 31.4 317 356
UBD/Alpha-Helix/UBA 9.40e-06 25.6 803 838
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl  w    + +s  + CP Cr
   Q: 317  CKICAENDKD-VKIEPCGHLMCTSCLTSW----Q-ESEGQGCPFCR 356
           99********.******************....5.555555****8 PP
   

   UBD/Alpha-Helix/UBA
   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyL 38
           +++ +e+l+++G++ +++++aL  a+nn+e+A + L
   Q: 803  LSSEIENLMSQGYSYQDIQKALVIAHNNIEMAKNIL 838
           6788****************************9988 PP
   
Organism Cavia porcellus
Protein Sequence
(Fasta)
QVVRLCQNPK LALKNSPPYI LDLLPDTYQH LRTILSRYEG KMETLGENEY FRVFMENLMK 60
KTKQTISLFK EGKERMYEEN SQPRRNLTKL SLIFSHMLAE LKGIFPSGLF QGDSFRITKA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cpo-021453|E3,RING;UBD,UBA|Cavia porcellus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAGGTGGTGC GGTTGTGTCA GAACCCAAAG CTGGCGCTAA AGAATAGTCC GCCTTATATT 60
TTAGACCTGT TGCCCGACAC CTACCAACAT CTTCGTACTA TCTTGTCAAG ATACGAGGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cpo-021453|E3,RING;UBD,UBA|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3
PF00627--UBA
SMART

SM00184--RING
SM00165--UBA
Gene Ontology

GO:0005829--C:cytosol
GO:0016600--C:flotillin complex
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0043066--P:negative regulation of apoptotic process
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0048260--P:positive regulation of receptor-mediated endocytosis
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002357 Ailuropoda melanoleuca 90.50 0.00e+00 1477.00
IUUC-Apl-004041 Anas platyrhynchos 84.05 0.00e+00 1386.00
IUUC-Aca-004899 Anolis carolinensis 81.58 0.00e+00 1274.00
IUUC-Ame-010746 Astyanax mexicanus 59.14 0.00e+00 633.00
IUUC-Bta-012759 Bos taurus 90.65 0.00e+00 1484.00
IUUC-Cja-019207 Callithrix jacchus 91.20 0.00e+00 1489.00
IUUC-Cfa-020897 Canis familiaris 90.77 0.00e+00 1461.00
IUUC-Csa-023136 Chlorocebus sabaeus 91.08 0.00e+00 1476.00
IUUC-Cho-024282 Choloepus hoffmanni 82.77 0.00e+00 1198.00
IUUC-Csv-025938 Ciona savignyi 69.47 2.00e-167 581.00
IUUC-Dre-027644 Danio rerio 67.58 0.00e+00 988.00
IUUC-Dno-030025 Dasypus novemcinctus 92.26 0.00e+00 1488.00
IUUC-Ete-033118 Echinops telfairi 78.85 0.00e+00 824.00
IUUC-Eca-033900 Equus caballus 92.97 0.00e+00 1515.00
IUUC-Eeu-035142 Erinaceus europaeus 85.22 0.00e+00 956.00
IUUC-Fca-035455 Felis catus 90.77 0.00e+00 1461.00
IUUC-Fal-037182 Ficedula albicollis 96.19 0.00e+00 869.00
IUUC-Gmo-038698 Gadus morhua 86.44 0.00e+00 836.00
IUUC-Gga-040438 Gallus gallus 83.59 0.00e+00 1380.00
IUUC-Gac-042166 Gasterosteus aculeatus 72.94 0.00e+00 837.00
IUUC-Ggo-045618 Gorilla gorilla 91.90 0.00e+00 1491.00
IUUC-Hsa-046177 Homo sapiens 91.43 0.00e+00 1479.00
IUUC-Itr-048795 Ictidomys tridecemlineatus 95.92 0.00e+00 1011.00
IUUC-Lch-050095 Latimeria chalumnae 72.09 0.00e+00 1127.00
IUUC-Loc-052570 Lepisosteus oculatus 70.99 0.00e+00 1089.00
IUUC-Laf-054008 Loxodonta africana 89.32 0.00e+00 1472.00
IUUC-Mcc-054676 Macaca mulatta 90.96 0.00e+00 1472.00
IUUC-Mga-059239 Meleagris gallopavo 82.65 0.00e+00 1373.00
IUUC-Mmr-060907 Microcebus murinus 89.67 0.00e+00 1456.00
IUUC-Mdo-062595 Monodelphis domestica 87.51 0.00e+00 1422.00
IUUC-Mmu-063725 Mus musculus 91.91 0.00e+00 1542.00
IUUC-Mpu-066771 Mustela putorius furo 90.74 0.00e+00 1473.00
IUUC-Mlu-067206 Myotis lucifugus 75.82 0.00e+00 1088.00
IUUC-Nle-069285 Nomascus leucogenys 88.73 0.00e+00 1381.00
IUUC-Opr-071026 Ochotona princeps 90.72 0.00e+00 1480.00
IUUC-Ont-071954 Oreochromis niloticus 68.69 0.00e+00 1000.00
IUUC-Ocu-074657 Oryctolagus cuniculus 91.20 0.00e+00 1468.00
IUUC-Ola-087165 Oryzias latipes 67.37 0.00e+00 1017.00
IUUC-Oga-088198 Otolemur garnettii 79.86 0.00e+00 1263.00
IUUC-Oar-090258 Ovis aries 90.41 0.00e+00 1457.00
IUUC-Ptr-090710 Pan troglodytes 91.43 0.00e+00 1479.00
IUUC-Pan-092785 Papio anubis 91.08 0.00e+00 1474.00
IUUC-Psi-093431 Pelodiscus sinensis 75.18 0.00e+00 723.00
IUUC-Pfo-096990 Poecilia formosa 89.79 0.00e+00 785.00
IUUC-Pab-098526 Pongo abelii 91.20 0.00e+00 1476.00
IUUC-Pca-100984 Procavia capensis 76.26 4.00e-163 568.00
IUUC-Pva-102352 Pteropus vampyrus 97.82 0.00e+00 840.00
IUUC-Rno-105876 Rattus norvegicus 91.78 0.00e+00 1516.00
IUUC-Sha-107588 Sarcophilus harrisii 85.75 0.00e+00 1232.00
IUUC-Sar-112959 Sorex araneus 87.44 0.00e+00 1441.00
IUUC-Ssc-115261 Sus scrofa 91.22 0.00e+00 1479.00
IUUC-Tgu-116580 Taeniopygia guttata 81.19 0.00e+00 1288.00
IUUC-Tru-118731 Takifugu rubripes 66.78 0.00e+00 998.00
IUUC-Tsy-118982 Tarsius syrichta 84.58 0.00e+00 1027.00
IUUC-Tni-120725 Tetraodon nigroviridis 67.75 0.00e+00 1007.00
IUUC-Tbe-128018 Tupaia belangeri 94.45 0.00e+00 1152.00
IUUC-Ttr-128927 Tursiops truncatus 90.87 0.00e+00 1502.00
IUUC-Vpa-130369 Vicugna pacos 90.04 0.00e+00 1408.00
IUUC-Xtr-132474 Xenopus tropicalis 72.82 0.00e+00 1107.00
Created Date 25-Jun-2017

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