iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ppa-095771

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Defective in cullin neddylation protein

Genbank Nucleotide ID

DS545215

Gene Name

PHYPADRAFT_172065

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S198_164V6	PP1S198_164V6.1	PP1S198_164V6.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	3.20e-79	266.1	36	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfk 95
           ++++lee++ +Ykd ++d+i ++g++ fc+dl+vdp d+++Lv++w+++aat++efs++ef +gl+++g+ds++kl+  l+ l+ elkde+kf+
   Q: 36   DPRHLEEFYLKYKDAYSDMIMVDGVSAFCDDLQVDPGDVVMLVISWHMKAATMSEFSKQEFSNGLQSIGVDSLDKLKSLLPYLRAELKDEHKFR 129
           7899****************************************************************************************** PP
   S: 96   diYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
           +iY+faf++ak+kgqksl+ldta+ +w+Ll+aer ++l+d w++fL+ +++k+iskDtW +lL+fs++i + lsnYd+egaWP+liDefveyl
   Q: 130  EIYNFAFSWAKEKGQKSLALDTALGMWQLLFAERVWPLVDPWCQFLQAKHNKAISKDTWVQLLDFSRTIVPSLSNYDAEGAWPYLIDEFVEYL 222
           *******************************************************************************************97 PP

Organism

Physcomitrella patens

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MCSEKAALTA LKASDWNLEG AFENFYNQPP ARPLVDPRHL EEFYLKYKDA YSDMIMVDGV 60
SAFCDDLQVD PGDVVMLVIS WHMKAATMSE FSKQEFSNGL QSIGVDSLDK LKSLLPYLRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGCAGTG AAAAGGCCGC TCTGACAGCC TTGAAGGCTA GCGATTGGAA CTTGGAAGGA 60
GCTTTTGAAA ACTTTTACAA CCAGCCACCT GCTAGACCAC TTGTAGATCC ACGGCATTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

KEGG

ppp:PHYPADRAFT_172065

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013561	Bos taurus	43.86	3.00e-54	204.00
IUUC-Cfa-020523	Canis familiaris	43.86	3.00e-54	204.00
IUUC-Csv-025976	Ciona savignyi	41.14	1.00e-35	142.00
IUUC-Dno-029524	Dasypus novemcinctus	44.16	9.00e-55	205.00
IUUC-Mpu-066870	Mustela putorius furo	43.86	3.00e-54	204.00
IUUC-Ocu-074349	Oryctolagus cuniculus	44.68	4.00e-55	207.00
IUUC-Psi-093029	Pelodiscus sinensis	44.59	7.00e-55	206.00
IUUC-Pab-098197	Pongo abelii	43.91	2.00e-54	204.00
IUUC-Ptt-103979	Puccinia triticina	33.33	7.00e-04	37.70
IUUC-Sar-113248	Sorex araneus	44.39	7.00e-41	159.00
IUUC-Sre-115221	Sporisorium reilianum	31.41	1.00e-22	99.40
IUUC-Uma-129364	Ustilago maydis	33.01	2.00e-29	121.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence