iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000001293.3	ENSMMUT00000032864.3	ENSMMUP00000030750.3
ENSMMUG00000001293.3	ENSMMUT00000001833.3	ENSMMUP00000001729.3
ENSMMUG00000001293.3	ENSMMUT00000076916.1	ENSMMUP00000057051.1
ENSMMUG00000001293.3	ENSMMUT00000043859.2	ENSMMUP00000036846.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-27	94.1	332	362
UBD/Beta-Prp	2.40e-41	143.0	330	606

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++v++++f ++  ll++G+ D  i++W++
   Q: 332  HLSEVNAVRFgPNsSLLATGGADRLIHLWNV 362
           99*********7779***************7 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghed 95
           ++h s +++v f p++sllatg++d+ i +w+v   k     +   a+  +++ sp+g  + ++   +++++w +   +   tl+gh+d
   Q: 330  DAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSK-----EPSPAGLGSLCVSPSG--IFSATYNQAAQLWKVGEAQSKETLSGHKD 411
           78999999*************************9944.....589999*********8..88889999********************* PP
   S: 96   svlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++   + +      +++v+
   Q: 412  KVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIP--VQGRVT 494
           **********************************9.666655...4555555556*************************5..589*** PP
   S: 185  slsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvi 268
           sls+++++ +l+s+s+d+t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs Dg ++iWd+++g+l + lq+++ + +
   Q: 495  SLSLSHDQLHLLSCSRDNTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSYDGALYIWDVDTGKLESRLQGPHCTAV 582
           **************************888833334444555556666.8899*********************************7777 PP
   S: 269  svavlsfgdnvlvlgsedskvniw 292
              +++++++++v++++  kv +w
   Q: 583  NAVAWCYSGSHVVSVDQGRKVVLW 606
           77778************99**999 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAGPGVPGAP VARWKRHIVW QLRLRDRMQK ALFLELVPAY NHLLEKAELL DKFSKKLQPE 60
PNSVTPTTHQ GPWEESGLDS DQVPSLPTLR VKWQEEEEGL RLVCGEVMVP RRGALGRLGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGGGC CCGGCGTCCC CGGCGCCCCC GTAGCCCGAT GGAAACGCCA CATTGTGTGG 60
CAGCTGCGTC TTCGGGACCG TATGCAAAAG GCGCTCTTCC TGGAGCTGGT GCCGGCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	65.66	0.00e+00	721.00
IUUC-Ame-011152	Astyanax mexicanus	39.97	2.00e-107	383.00
IUUC-Bta-013118	Bos taurus	80.13	0.00e+00	862.00
IUUC-Cja-020002	Callithrix jacchus	84.52	0.00e+00	921.00
IUUC-Cfa-020878	Canis familiaris	77.49	0.00e+00	853.00
IUUC-Cpo-022476	Cavia porcellus	78.25	0.00e+00	847.00
IUUC-Csa-024134	Chlorocebus sabaeus	91.63	0.00e+00	1001.00
IUUC-Cho-024853	Choloepus hoffmanni	66.73	5.00e-167	580.00
IUUC-Dre-027949	Danio rerio	40.76	1.00e-117	417.00
IUUC-Dno-029683	Dasypus novemcinctus	79.40	0.00e+00	734.00
IUUC-Dor-030897	Dipodomys ordii	73.14	0.00e+00	855.00
IUUC-Ete-032957	Echinops telfairi	88.48	5.00e-119	421.00
IUUC-Eca-033303	Equus caballus	84.26	2.00e-149	521.00
IUUC-Eeu-035336	Erinaceus europaeus	69.23	2.00e-137	483.00
IUUC-Fca-036232	Felis catus	80.48	0.00e+00	925.00
IUUC-Ggo-045130	Gorilla gorilla	91.81	0.00e+00	682.00
IUUC-Hsa-046359	Homo sapiens	90.28	0.00e+00	922.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	80.98	0.00e+00	892.00
IUUC-Lch-050669	Latimeria chalumnae	53.01	6.00e-93	333.00
IUUC-Loc-052789	Lepisosteus oculatus	42.17	2.00e-105	376.00
IUUC-Laf-053699	Loxodonta africana	79.68	0.00e+00	859.00
IUUC-Meu-056639	Macropus eugenii	45.03	2.00e-96	346.00
IUUC-Mmr-061314	Microcebus murinus	76.71	0.00e+00	787.00
IUUC-Mdo-061841	Monodelphis domestica	60.22	0.00e+00	639.00
IUUC-Mmu-064065	Mus musculus	77.76	0.00e+00	870.00
IUUC-Mpu-066742	Mustela putorius furo	78.51	0.00e+00	831.00
IUUC-Mlu-067019	Myotis lucifugus	83.37	0.00e+00	629.00
IUUC-Nle-069037	Nomascus leucogenys	90.12	0.00e+00	973.00
IUUC-Opr-071039	Ochotona princeps	76.41	0.00e+00	826.00
IUUC-Oan-073431	Ornithorhynchus anatinus	67.59	4.00e-126	444.00
IUUC-Ocu-074772	Oryctolagus cuniculus	79.25	0.00e+00	770.00
IUUC-Oga-088188	Otolemur garnettii	81.26	0.00e+00	848.00
IUUC-Oar-090231	Ovis aries	74.35	0.00e+00	836.00
IUUC-Ptr-091434	Pan troglodytes	89.79	0.00e+00	908.00
IUUC-Pan-091868	Papio anubis	93.05	0.00e+00	982.00
IUUC-Psi-093652	Pelodiscus sinensis	61.02	3.00e-154	538.00
IUUC-Pab-097776	Pongo abelii	88.96	0.00e+00	890.00
IUUC-Pca-100220	Procavia capensis	68.66	5.00e-90	325.00
IUUC-Pva-103135	Pteropus vampyrus	81.19	0.00e+00	809.00
IUUC-Rno-105529	Rattus norvegicus	76.24	0.00e+00	898.00
IUUC-Sha-107062	Sarcophilus harrisii	60.89	0.00e+00	672.00
IUUC-Sar-113109	Sorex araneus	83.48	5.00e-101	361.00
IUUC-Ssc-115271	Sus scrofa	81.00	0.00e+00	842.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence