iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089879

Ensembl Protein ID

ENSOARP00000010892.1

UniProt Accession

W5PKC1; W5PKC1_SHEEP

Genbank Protein ID

ENSOARP00000010892

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01059445

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010155.1	ENSOART00000011050.1	ENSOARP00000010892.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	4.10e-50	171.1	31	223

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC+++fC++Clkqy++l+i+eg+ + i+cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+++
   Q: 31   CKLCLCEQSLDKMTTLQECRCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHgtLQEAEIAC-LVPVDQFQLYQRLKFEREVHLDPCR 119
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++++  + + vec++c+ +fC++Ck++wH+++sC++ +     te   + +   + +ea +k+Cp C+vyie+neg
   Q: 120  TWCPVADCQTVCPVATSDpgQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPGILPTE---HGTLFGTEAEAPIKQCPVCRVYIERNEG 206
           ************99988777899999***************************999999...8899999********************* PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 207  CAQMMCKNCKHTFCWYC 223
           ***************** PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MGSVGRLHCL TMTAAENPTP GDLALAPLVT CKLCLCEQSL DKMTTLQECR CIFCTACLKQ 60
YMQLAIREGC GSPITCPDMV CLNHGTLQEA EIACLVPVDQ FQLYQRLKFE REVHLDPCRT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATTGAGGA GACTGAAGGA GGCTGAGGAC AAGCTGATGG GCTCAGTGGG TAGGCTCCAC 60
TGTCTGACCA TGACGGCTGC CGAAAATCCC ACGCCTGGAG ACCTGGCCCT GGCGCCCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

oas:101122473

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	92.43	4.00e-165	573.00
IUUC-Apl-004112	Anas platyrhynchos	82.27	2.00e-129	454.00
IUUC-Aca-004533	Anolis carolinensis	76.39	1.00e-136	479.00
IUUC-Bta-012641	Bos taurus	99.34	6.00e-179	619.00
IUUC-Cja-019626	Callithrix jacchus	78.95	1.00e-136	478.00
IUUC-Cfa-020702	Canis familiaris	93.42	6.00e-168	582.00
IUUC-Cpo-022147	Cavia porcellus	95.07	4.00e-170	590.00
IUUC-Csa-023473	Chlorocebus sabaeus	94.41	1.00e-169	588.00
IUUC-Cho-024298	Choloepus hoffmanni	90.31	1.00e-138	484.00
IUUC-Dre-028099	Danio rerio	64.29	3.00e-90	324.00
IUUC-Dno-029122	Dasypus novemcinctus	87.87	4.00e-155	540.00
IUUC-Dor-030669	Dipodomys ordii	95.71	5.00e-132	462.00
IUUC-Ete-033141	Echinops telfairi	80.26	2.00e-129	454.00
IUUC-Eca-034360	Equus caballus	95.07	3.00e-170	590.00
IUUC-Eeu-034538	Erinaceus europaeus	71.83	3.00e-84	304.00
IUUC-Fca-036055	Felis catus	92.11	1.00e-165	575.00
IUUC-Fal-037339	Ficedula albicollis	82.14	5.00e-133	466.00
IUUC-Gmo-038780	Gadus morhua	59.93	2.00e-83	301.00
IUUC-Gga-040256	Gallus gallus	80.14	4.00e-132	463.00
IUUC-Gac-042127	Gasterosteus aculeatus	61.30	2.00e-92	332.00
IUUC-Ggo-044867	Gorilla gorilla	95.39	1.00e-170	592.00
IUUC-Hsa-046928	Homo sapiens	95.07	3.00e-170	590.00
IUUC-Hvu-047484	Hordeum vulgare	30.48	2.00e-17	83.20
IUUC-Itr-048250	Ictidomys tridecemlineatus	95.34	8.00e-108	382.00
IUUC-Lch-050168	Latimeria chalumnae	73.20	1.00e-129	455.00
IUUC-Lpe-051649	Leersia perrieri	29.56	5.00e-16	80.10
IUUC-Loc-052150	Lepisosteus oculatus	60.93	6.00e-88	317.00
IUUC-Laf-053967	Loxodonta africana	94.08	1.00e-167	582.00
IUUC-Mcc-055898	Macaca mulatta	94.41	1.00e-169	588.00
IUUC-Meu-056628	Macropus eugenii	94.81	5.00e-42	164.00
IUUC-Mtr-057989	Medicago truncatula	26.76	6.00e-19	87.40
IUUC-Mga-059820	Meleagris gallopavo	79.08	2.00e-130	458.00
IUUC-Mmr-060680	Microcebus murinus	93.75	8.00e-168	582.00
IUUC-Mdo-062839	Monodelphis domestica	85.25	2.00e-152	531.00
IUUC-Mmu-063339	Mus musculus	87.50	5.00e-147	513.00
IUUC-Mac-065414	Musa acuminata	28.44	2.00e-18	86.30
IUUC-Mpu-065973	Mustela putorius furo	91.45	9.00e-164	569.00
IUUC-Mlu-067112	Myotis lucifugus	93.75	1.00e-159	555.00
IUUC-Nle-069795	Nomascus leucogenys	94.74	3.00e-170	590.00
IUUC-Opr-070390	Ochotona princeps	87.83	2.00e-151	527.00
IUUC-Ont-072329	Oreochromis niloticus	63.57	7.00e-88	317.00
IUUC-Oan-072980	Ornithorhynchus anatinus	83.70	3.00e-137	480.00
IUUC-Ocu-073845	Oryctolagus cuniculus	94.41	1.00e-169	588.00
IUUC-Ola-086872	Oryzias latipes	61.42	5.00e-84	303.00
IUUC-Oga-088954	Otolemur garnettii	94.08	3.00e-167	580.00
IUUC-Ptr-090685	Pan troglodytes	95.07	3.00e-170	590.00
IUUC-Pan-092086	Papio anubis	94.08	2.00e-169	587.00
IUUC-Psi-093481	Pelodiscus sinensis	81.58	7.00e-139	486.00
IUUC-Pfo-096065	Poecilia formosa	62.41	4.00e-91	327.00
IUUC-Pab-098031	Pongo abelii	94.74	9.00e-170	588.00
IUUC-Pca-100936	Procavia capensis	92.76	2.00e-164	571.00
IUUC-Pva-102864	Pteropus vampyrus	83.55	2.00e-145	507.00
IUUC-Rno-105503	Rattus norvegicus	87.50	1.00e-146	512.00
IUUC-Sha-107425	Sarcophilus harrisii	84.59	2.00e-151	528.00
IUUC-Stu-112736	Solanum tuberosum	27.15	2.00e-17	82.40
IUUC-Ssc-115458	Sus scrofa	95.44	8.00e-162	562.00
IUUC-Tgu-117226	Taeniopygia guttata	81.07	7.00e-133	466.00
IUUC-Tru-118362	Takifugu rubripes	64.29	2.00e-92	332.00
IUUC-Tsy-119255	Tarsius syrichta	95.72	1.00e-172	598.00
IUUC-Tni-120140	Tetraodon nigroviridis	62.09	2.00e-88	318.00
IUUC-Tae-124420	Triticum aestivum	31.71	7.00e-18	85.50
IUUC-Tbe-127306	Tupaia belangeri	95.39	5.00e-170	589.00
IUUC-Ttr-128923	Tursiops truncatus	95.72	4.00e-162	563.00
IUUC-Vpa-130148	Vicugna pacos	95.39	4.00e-170	590.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence