iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067132

Ensembl Protein ID

ENSMLUP00000007981.2

UniProt Accession

G1PC51; G1PC51_MYOLU

Genbank Protein ID

ENSMLUP00000007981

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02046419

Gene Name

NCK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000008767.2	ENSMLUT00000008759.2	ENSMLUP00000007981.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.00e-35	120.6	121	180

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +++vq+ly++++++++eL+++kG++++viek e+d +W+k+ k+++g+ Gl+P+n+v+ l+
   Q: 121  LHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWWKC-KNARGQVGLVPKNYVVVLS 180
           689**************************************.7**************9886 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

GLGKTKRKTS ARDASPTPST DAEYPANGGA DRIYDLNIPA FVKFAYVAER EDELSLVKGS 60
RVTVMEKCSD GWWRGSYNGQ IGWFPSNYVL EEVDEAAAES PSFPSLRRGA PVSNGQGARV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCTGGGCA AGACCAAAAG GAAGACGAGC GCGAGGGACG CGTCCCCAAC GCCCAGCACG 60
GATGCCGAGT ACCCTGCCAA TGGGGGCGCC GACCGCATCT ACGACCTCAA CATCCCGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR017304--NCK
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0012506--C:vesicle membrane
GO:0007015--P:actin filament organization
GO:0016477--P:cell migration
GO:0048013--P:ephrin receptor signaling pathway
GO:0030032--P:lamellipodium assembly
GO:1903912--P:negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
GO:1903898--P:negative regulation of PERK-mediated unfolded protein response
GO:1990441--P:negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:1902237--P:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0036493--P:positive regulation of translation in response to endoplasmic reticulum stress

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001404	Ailuropoda melanoleuca	95.41	3.00e-166	577.00
IUUC-Apl-003456	Anas platyrhynchos	88.85	4.00e-158	550.00
IUUC-Aca-005105	Anolis carolinensis	87.87	8.00e-157	546.00
IUUC-Bta-012424	Bos taurus	84.92	2.00e-138	485.00
IUUC-Cja-019898	Callithrix jacchus	94.10	4.00e-165	573.00
IUUC-Cfa-020830	Canis familiaris	94.43	6.00e-165	573.00
IUUC-Csa-023693	Chlorocebus sabaeus	94.10	5.00e-165	573.00
IUUC-Dno-028973	Dasypus novemcinctus	90.49	5.00e-160	556.00
IUUC-Dor-031003	Dipodomys ordii	93.09	2.00e-156	545.00
IUUC-Ete-032792	Echinops telfairi	82.20	2.00e-144	505.00
IUUC-Eca-033656	Equus caballus	95.08	6.00e-166	576.00
IUUC-Eeu-035169	Erinaceus europaeus	83.26	8.00e-96	342.00
IUUC-Fca-036347	Felis catus	95.74	2.00e-166	578.00
IUUC-Fal-037095	Ficedula albicollis	88.52	4.00e-158	550.00
IUUC-Gga-040155	Gallus gallus	88.85	3.00e-158	551.00
IUUC-Ggo-044805	Gorilla gorilla	94.43	1.00e-165	575.00
IUUC-Hsa-046585	Homo sapiens	94.43	1.00e-165	575.00
IUUC-Itr-048887	Ictidomys tridecemlineatus	91.80	2.00e-155	541.00
IUUC-Lch-049795	Latimeria chalumnae	85.25	1.00e-151	529.00
IUUC-Laf-054228	Loxodonta africana	91.80	2.00e-161	561.00
IUUC-Mcc-055402	Macaca mulatta	94.10	5.00e-165	573.00
IUUC-Mga-059374	Meleagris gallopavo	88.85	3.00e-158	551.00
IUUC-Mmr-061453	Microcebus murinus	94.43	1.00e-165	575.00
IUUC-Mdo-063080	Monodelphis domestica	87.21	1.00e-156	545.00
IUUC-Mmu-063529	Mus musculus	92.79	3.00e-157	547.00
IUUC-Mpu-066815	Mustela putorius furo	95.41	3.00e-166	577.00
IUUC-Nle-069371	Nomascus leucogenys	94.43	1.00e-165	575.00
IUUC-Opr-070948	Ochotona princeps	92.38	2.00e-150	525.00
IUUC-Oan-073304	Ornithorhynchus anatinus	88.56	4.00e-158	550.00
IUUC-Ocu-074783	Oryctolagus cuniculus	93.77	2.00e-157	548.00
IUUC-Oga-088391	Otolemur garnettii	94.43	5.00e-160	556.00
IUUC-Ptr-090975	Pan troglodytes	94.43	1.00e-165	575.00
IUUC-Pan-092287	Papio anubis	94.10	5.00e-165	573.00
IUUC-Psi-093413	Pelodiscus sinensis	88.85	4.00e-158	550.00
IUUC-Pab-098756	Pongo abelii	94.43	1.00e-165	575.00
IUUC-Pca-100235	Procavia capensis	76.07	2.00e-136	478.00
IUUC-Pva-102294	Pteropus vampyrus	97.05	1.00e-169	588.00
IUUC-Rno-105090	Rattus norvegicus	92.79	4.00e-157	547.00
IUUC-Sha-107521	Sarcophilus harrisii	87.87	1.00e-157	548.00
IUUC-Sar-113697	Sorex araneus	85.11	2.00e-143	501.00
IUUC-Tgu-116559	Taeniopygia guttata	86.23	2.00e-150	525.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence