iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132915

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Katanin p80 WD40 repeat-containing subunit B1; p80 katanin

Genbank Nucleotide ID

AAMC01003389

Gene Name

katnb1; KATNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000025041.2	ENSXETT00000053740.2	ENSXETP00000053740.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.50e-42	140.4	145	180
UBD/Beta-Prp	2.60e-58	197.7	15	270

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gHt  v+cl+f +d + l+s+sdD+++k+WDl+ g+
   Q: 145  GHTQAVRCLRFsPDgKWLASASDDHSVKLWDLTAGK 180
           8***********999*****************9986 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           ++ +h +sv ++v  + +++l+atg++d ++ +w+v +++++ sl gh+ +v +v+f++ ++++v gs+ + ++vwdl++ k+++tl g
   Q: 15   EIVAHGSSVSSVVLGKSSGRLVATGGDDCRVNLWSVNKPNCIMSLTGHTTPVESVRFNNAEELIVAGSQSGSLRVWDLEAAKILRTLMG 103
           5667778888888889************************************************************************* PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h+++v+sl+f+p+gd+++sGs d  i++wd++ + c+    +gh+++v+c++++pdg+ l+s+s+D  v+lWdl  gk++ +l++ h++
   Q: 104  HKANVCSLDFHPYGDFVASGSLDTNIKLWDVRRKGCVF-RYKGHTQAVRCLRFSPDGKWLASASDDHSVKLWDLTAGKMMAELSE-HKG 190
           *************************************9.9*******************************************99.*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktl 260
           +v+ ++f++n   l+sgs d+tv++wdl++ + +   +g t +v+  + +  +++  + +g+ D  +r++  + +++  t+
   Q: 191  PVNIIEFHPNEYLLASGSADRTVRFWDLEKFQLIGCTEGETIPVSKRAILfsSDGGCIFCGGRDA-LRVYGWEPDQCFDTV 270
           *****************************************888765544449999999999875.566655777776665 PP

Organism

Xenopus tropicalis

Functional Description
(View)

Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.

Protein Sequence
(Fasta)

MATPSPTKTT WKLQEIVAHG SSVSSVVLGK SSGRLVATGG DDCRVNLWSV NKPNCIMSLT 60
GHTTPVESVR FNNAEELIVA GSQSGSLRVW DLEAAKILRT LMGHKANVCS LDFHPYGDFV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGAGTTAC GCTGATACGG AACTCCGTGT GCGTCCCCGC GCTTACGTGT GACGTGCGCC 60
AGTCTCGCGT GATGAGCGTT GTGTTGGGAT TGTAGGGGAA AGAGTTTGCA GGTACTATAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0030901--P:midbrain development
GO:0007067--P:mitotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	47.27	3.00e-87	317.00
IUUC-Aml-002187	Ailuropoda melanoleuca	68.19	0.00e+00	875.00
IUUC-Atr-002899	Amborella trichopoda	49.55	2.00e-100	359.00
IUUC-Apl-003305	Anas platyrhynchos	69.15	0.00e+00	926.00
IUUC-Aca-004635	Anolis carolinensis	72.21	0.00e+00	893.00
IUUC-Aly-005711	Arabidopsis lyrata	50.16	6.00e-101	362.00
IUUC-Ath-007606	Arabidopsis thaliana	50.16	9.00e-101	361.00
IUUC-Ame-010870	Astyanax mexicanus	56.67	9.00e-96	343.00
IUUC-Bta-012527	Bos taurus	72.15	0.00e+00	939.00
IUUC-Bdi-014652	Brachypodium distachyon	52.98	2.00e-103	370.00
IUUC-Bol-015242	Brassica oleracea	49.05	1.00e-99	357.00
IUUC-Bra-017390	Brassica rapa	49.68	1.00e-99	357.00
IUUC-Cja-019706	Callithrix jacchus	71.54	0.00e+00	882.00
IUUC-Cfa-020139	Canis familiaris	60.51	3.00e-170	591.00
IUUC-Cpo-021710	Cavia porcellus	72.43	0.00e+00	926.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	43.05	4.00e-69	256.00
IUUC-Csa-023546	Chlorocebus sabaeus	72.58	0.00e+00	856.00
IUUC-Cin-025156	Ciona intestinalis	42.21	3.00e-153	535.00
IUUC-Csv-025962	Ciona savignyi	51.03	1.00e-89	322.00
IUUC-Dre-028215	Danio rerio	60.06	0.00e+00	838.00
IUUC-Dno-029314	Dasypus novemcinctus	71.09	0.00e+00	897.00
IUUC-Dor-030482	Dipodomys ordii	73.03	0.00e+00	956.00
IUUC-Dme-032188	Drosophila melanogaster	38.96	1.00e-58	221.00
IUUC-Eca-034143	Equus caballus	71.68	0.00e+00	923.00
IUUC-Fca-035924	Felis catus	72.05	0.00e+00	915.00
IUUC-Fal-037387	Ficedula albicollis	70.45	0.00e+00	911.00
IUUC-Gmo-038692	Gadus morhua	62.35	2.00e-153	535.00
IUUC-Gga-040597	Gallus gallus	69.81	0.00e+00	950.00
IUUC-Gac-042004	Gasterosteus aculeatus	60.47	0.00e+00	816.00
IUUC-Gma-044134	Glycine max	51.99	3.00e-99	356.00
IUUC-Ggo-044761	Gorilla gorilla	72.73	0.00e+00	884.00
IUUC-Hsa-045698	Homo sapiens	73.17	0.00e+00	902.00
IUUC-Hvu-047649	Hordeum vulgare	52.65	7.00e-104	371.00
IUUC-Itr-048697	Ictidomys tridecemlineatus	72.28	0.00e+00	913.00
IUUC-Lch-049674	Latimeria chalumnae	66.86	0.00e+00	899.00
IUUC-Lpe-051597	Leersia perrieri	48.17	1.00e-94	340.00
IUUC-Loc-052623	Lepisosteus oculatus	64.08	0.00e+00	876.00
IUUC-Laf-054587	Loxodonta africana	72.58	0.00e+00	942.00
IUUC-Mcc-055851	Macaca mulatta	72.58	0.00e+00	884.00
IUUC-Meu-056704	Macropus eugenii	72.54	0.00e+00	984.00
IUUC-Mor-057251	Magnaporthe oryzae	33.33	8.00e-28	118.00
IUUC-Mtr-058053	Medicago truncatula	51.66	1.00e-103	370.00
IUUC-Mga-059608	Meleagris gallopavo	69.57	0.00e+00	947.00
IUUC-Mmr-061154	Microcebus murinus	69.77	0.00e+00	902.00
IUUC-Mdo-062365	Monodelphis domestica	68.55	0.00e+00	912.00
IUUC-Mmu-063754	Mus musculus	73.17	0.00e+00	927.00
IUUC-Mac-064439	Musa acuminata	50.50	1.00e-99	357.00
IUUC-Mpu-066245	Mustela putorius furo	72.20	0.00e+00	900.00
IUUC-Mlu-067692	Myotis lucifugus	72.22	0.00e+00	914.00
IUUC-Nle-070051	Nomascus leucogenys	72.13	0.00e+00	881.00
IUUC-Opr-070855	Ochotona princeps	72.50	0.00e+00	923.00
IUUC-Ont-071883	Oreochromis niloticus	57.87	0.00e+00	823.00
IUUC-Oan-073293	Ornithorhynchus anatinus	73.00	0.00e+00	878.00
IUUC-Ocu-074644	Oryctolagus cuniculus	73.32	0.00e+00	932.00
IUUC-Oba-075448	Oryza barthii	50.00	1.00e-104	374.00
IUUC-Obr-076385	Oryza brachyantha	52.65	7.00e-104	371.00
IUUC-Ogl-077427	Oryza glaberrima	52.98	1.00e-104	374.00
IUUC-Ogu-079022	Oryza glumaepatula	49.35	1.00e-97	351.00
IUUC-Oin-079811	Oryza indica	52.54	7.00e-102	365.00
IUUC-Olo-080245	Oryza longistaminata	52.54	1.00e-101	364.00
IUUC-Ome-081239	Oryza meridionalis	52.70	2.00e-101	363.00
IUUC-Oni-082640	Oryza nivara	50.00	1.00e-104	374.00
IUUC-Opu-083748	Oryza punctata	50.31	4.00e-104	372.00
IUUC-Oru-084609	Oryza rufipogon	50.00	1.00e-104	374.00
IUUC-Osa-086267	Oryza sativa	49.68	5.00e-98	352.00
IUUC-Ola-087483	Oryzias latipes	55.63	0.00e+00	640.00
IUUC-Oga-087964	Otolemur garnettii	71.68	0.00e+00	934.00
IUUC-Oar-089483	Ovis aries	70.62	0.00e+00	902.00
IUUC-Ptr-091387	Pan troglodytes	73.17	0.00e+00	903.00
IUUC-Pan-092623	Papio anubis	72.58	0.00e+00	884.00
IUUC-Psi-093830	Pelodiscus sinensis	71.13	0.00e+00	941.00
IUUC-Pma-094135	Petromyzon marinus	41.86	5.00e-36	144.00
IUUC-Ppa-095379	Physcomitrella patens	52.72	7.00e-94	338.00
IUUC-Pfo-096755	Poecilia formosa	57.90	0.00e+00	799.00
IUUC-Pab-097564	Pongo abelii	70.78	0.00e+00	766.00
IUUC-Pop-099149	Populus trichocarpa	51.99	2.00e-103	369.00
IUUC-Pca-100357	Procavia capensis	85.71	2.00e-112	399.00
IUUC-Ppe-101237	Prunus persica	51.99	1.00e-103	370.00
IUUC-Pva-102397	Pteropus vampyrus	69.36	0.00e+00	854.00
IUUC-Rno-105349	Rattus norvegicus	73.17	0.00e+00	952.00
IUUC-Smo-109409	Selaginella moellendorffii	50.62	1.00e-99	357.00
IUUC-Sit-110360	Setaria italica	52.98	4.00e-104	372.00
IUUC-Sly-111307	Solanum lycopersicum	51.97	3.00e-98	352.00
IUUC-Stu-112053	Solanum tuberosum	48.64	3.00e-100	359.00
IUUC-Sar-112953	Sorex araneus	65.22	1.00e-86	313.00
IUUC-Sbi-114389	Sorghum bicolor	40.16	5.00e-93	335.00
IUUC-Ssc-115949	Sus scrofa	66.73	0.00e+00	649.00
IUUC-Tgu-117461	Taeniopygia guttata	69.32	0.00e+00	921.00
IUUC-Tru-117865	Takifugu rubripes	57.02	0.00e+00	781.00
IUUC-Tsy-119036	Tarsius syrichta	85.83	2.00e-61	229.00
IUUC-Tni-120903	Tetraodon nigroviridis	58.81	0.00e+00	769.00
IUUC-Tca-121185	Theobroma cacao	51.32	1.00e-101	364.00
IUUC-Tae-125307	Triticum aestivum	52.98	3.00e-104	372.00
IUUC-Tur-126181	Triticum urartu	43.55	5.00e-92	332.00
IUUC-Tbe-127518	Tupaia belangeri	59.40	8.00e-134	470.00
IUUC-Ttr-128172	Tursiops truncatus	71.83	0.00e+00	911.00
IUUC-Vda-129842	Verticillium dahliae	31.16	2.00e-28	120.00
IUUC-Vvi-131489	Vitis vinifera	52.65	2.00e-103	369.00
IUUC-Xma-134133	Xiphophorus maculatus	57.33	0.00e+00	786.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence