iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000016367.1	ENSSHAT00000019427.1	ENSSHAP00000019271.1
ENSSHAG00000016367.1	ENSSHAT00000019428.1	ENSSHAP00000019272.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	8.10e-98	328.5	54	243

Active Site

Position(s)	Description	Evidence
225	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 15   klksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleee 103
            l+++kvl++GagglGcEllKnL+l+G+++i+v+Dmdt++vsnlnrqFLfr++dvg+sKAevaae+l+++ p++ v++h ++i++ +++
   Q: 54   LLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDVGRSKAEVAAEFLNDRIPNCAVVPHFNKIQNFDDT 142
           589************************************************************************************** PP
   S: 104  ivFfkkfdvVvlaldnrearrkvnrlclna............rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlke 178
             F+++f+++v++ld++ arr++n +++++             +pli++gt+G++G++rvi++g+t+c++c+   +ppq ++P+ct+++
   Q: 143  --FYRQFHIIVCGLDSIIARRWINGMLISLlnyedgvldpssIIPLIDGGTEGFKGNARVILPGMTACIECTLelYPPQINFPMCTIAS 229
           ..***************************9*********************************************************** PP
   S: 179  tpnaaehtiewavl 192
           +p+ +eh+ie+a++
   Q: 230  MPRLPEHCIEYARI 243
           ***********933 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MVSNNEDEIM AVDGGCGDTG DWDGRWNHVK KFLERSGPFT HPDFEPSTES LQFLLDTCKV 60
LVIGAGGLGC ELLKNLALSG FRQIHVIDMD TIDVSNLNRQ FLFRPKDVGR SKAEVAAEFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTCTGGAGT TGGCCCAGCA GAGAATCTGG AACCAAGAAG TATCTCCTCT CTCAAGCACT 60
CACATCAGTG CCATCCTTCA TTAAGGTATG CTTTGTGTAT CAGCATTCTC CCTAACAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0005634--C:nucleus
GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0007113--P:endomitotic cell cycle
GO:0045116--P:protein neddylation
GO:0051726--P:regulation of cell cycle

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	46.31	1.00e-77	283.00
IUUC-Aml-001578	Ailuropoda melanoleuca	95.27	0.00e+00	892.00
IUUC-Atr-002591	Amborella trichopoda	49.13	2.00e-88	318.00
IUUC-Apl-003671	Anas platyrhynchos	90.95	0.00e+00	858.00
IUUC-Aca-004749	Anolis carolinensis	90.40	0.00e+00	821.00
IUUC-Aly-005747	Arabidopsis lyrata	48.35	2.00e-96	345.00
IUUC-Ath-006623	Arabidopsis thaliana	48.61	2.00e-96	345.00
IUUC-Ago-007934	Ashbya gossypii	44.34	9.00e-72	263.00
IUUC-Acl-008047	Aspergillus clavatus	49.65	7.00e-121	427.00
IUUC-Afl-008615	Aspergillus flavus	43.97	4.00e-78	285.00
IUUC-Afu-008996	Aspergillus fumigatus	50.47	3.00e-114	405.00
IUUC-Ani-009281	Aspergillus nidulans	43.53	3.00e-83	301.00
IUUC-Ang-009539	Aspergillus niger	50.59	5.00e-111	394.00
IUUC-Aor-010151	Aspergillus oryzae	48.56	6.00e-109	387.00
IUUC-Ate-010502	Aspergillus terreus	50.82	5.00e-113	400.00
IUUC-Ame-011837	Astyanax mexicanus	86.94	0.00e+00	788.00
IUUC-Bgr-012068	Blumeria graminis	50.24	1.00e-113	402.00
IUUC-Bta-013003	Bos taurus	96.15	0.00e+00	893.00
IUUC-Bci-013983	Botrytis cinerea	53.99	8.00e-125	440.00
IUUC-Bdi-014429	Brachypodium distachyon	47.76	5.00e-85	308.00
IUUC-Bol-015813	Brassica oleracea	48.87	3.00e-88	318.00
IUUC-Bra-018023	Brassica rapa	48.35	3.00e-85	308.00
IUUC-Cel-018684	Caenorhabditis elegans	52.34	1.00e-126	446.00
IUUC-Cja-019200	Callithrix jacchus	95.27	0.00e+00	882.00
IUUC-Cfa-021038	Canis familiaris	96.15	0.00e+00	894.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	48.29	7.00e-106	377.00
IUUC-Csa-024079	Chlorocebus sabaeus	95.02	0.00e+00	889.00
IUUC-Cho-025052	Choloepus hoffmanni	87.78	0.00e+00	800.00
IUUC-Cin-025113	Ciona intestinalis	68.03	3.00e-179	620.00
IUUC-Csv-026231	Ciona savignyi	66.06	2.00e-180	625.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	51.38	2.00e-125	442.00
IUUC-Cne-026850	Cryptococcus neoformans	48.24	5.00e-108	384.00
IUUC-Cme-027275	Cyanidioschyzon merolae	37.01	1.00e-69	256.00
IUUC-Dre-028751	Danio rerio	86.07	0.00e+00	794.00
IUUC-Dno-029571	Dasypus novemcinctus	95.70	0.00e+00	892.00
IUUC-Dor-030395	Dipodomys ordii	94.12	0.00e+00	862.00
IUUC-Dse-031329	Dothistroma septosporum	45.29	5.00e-103	367.00
IUUC-Dme-031776	Drosophila melanogaster	63.11	7.00e-160	556.00
IUUC-Ete-032894	Echinops telfairi	75.88	2.00e-68	253.00
IUUC-Eca-034389	Equus caballus	95.28	0.00e+00	892.00
IUUC-Eeu-035152	Erinaceus europaeus	83.83	0.00e+00	676.00
IUUC-Fca-036032	Felis catus	95.72	0.00e+00	895.00
IUUC-Fal-037506	Ficedula albicollis	90.05	0.00e+00	851.00
IUUC-Fox-037871	Fusarium oxysporum	54.11	5.00e-111	394.00
IUUC-Fso-038350	Fusarium solani	52.56	7.00e-123	433.00
IUUC-Gmo-039246	Gadus morhua	83.11	0.00e+00	759.00
IUUC-Ggr-039859	Gaeumannomyces graminis	53.60	4.00e-121	427.00
IUUC-Gga-040843	Gallus gallus	87.36	0.00e+00	822.00
IUUC-Gac-042601	Gasterosteus aculeatus	83.11	0.00e+00	771.00
IUUC-Gma-042744	Glycine max	50.52	2.00e-87	315.00
IUUC-Ggo-044788	Gorilla gorilla	95.03	0.00e+00	883.00
IUUC-Hsa-045849	Homo sapiens	95.48	0.00e+00	890.00
IUUC-Hvu-047819	Hordeum vulgare	49.86	2.00e-79	289.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	95.48	0.00e+00	889.00
IUUC-Kpa-049393	Komagataella pastoris	55.32	1.00e-103	369.00
IUUC-Lch-049471	Latimeria chalumnae	90.95	0.00e+00	828.00
IUUC-Lpe-051297	Leersia perrieri	47.84	1.00e-96	346.00
IUUC-Loc-052910	Lepisosteus oculatus	88.34	0.00e+00	812.00
IUUC-Lma-053181	Leptosphaeria maculans	50.34	6.00e-121	427.00
IUUC-Laf-054314	Loxodonta africana	95.07	0.00e+00	886.00
IUUC-Mcc-054870	Macaca mulatta	95.48	0.00e+00	891.00
IUUC-Meu-056574	Macropus eugenii	82.62	2.00e-136	478.00
IUUC-Mor-056919	Magnaporthe oryzae	54.19	3.00e-124	438.00
IUUC-Mpo-057614	Magnaporthe poae	54.68	2.00e-115	409.00
IUUC-Mtr-058110	Medicago truncatula	49.74	3.00e-86	312.00
IUUC-Mla-058949	Melampsora laricipopulina	52.81	1.00e-115	409.00
IUUC-Mga-059455	Meleagris gallopavo	90.72	0.00e+00	852.00
IUUC-Mvi-060270	Microbotryum violaceum	50.90	8.00e-119	420.00
IUUC-Mmr-061155	Microcebus murinus	92.43	0.00e+00	833.00
IUUC-Mdo-062037	Monodelphis domestica	99.06	0.00e+00	879.00
IUUC-Mmu-063670	Mus musculus	95.46	0.00e+00	888.00
IUUC-Mac-064711	Musa acuminata	48.64	5.00e-87	314.00
IUUC-Mpu-066734	Mustela putorius furo	95.72	0.00e+00	889.00
IUUC-Mlu-067068	Myotis lucifugus	95.55	0.00e+00	858.00
IUUC-Nfi-068349	Neosartorya fischeri	50.23	1.00e-113	402.00
IUUC-Ncr-068626	Neurospora crassa	53.00	2.00e-107	382.00
IUUC-Nle-069366	Nomascus leucogenys	87.25	0.00e+00	797.00
IUUC-Opr-070993	Ochotona princeps	90.00	3.00e-67	249.00
IUUC-Ont-072196	Oreochromis niloticus	86.49	0.00e+00	778.00
IUUC-Oan-073511	Ornithorhynchus anatinus	94.12	0.00e+00	879.00
IUUC-Ocu-073773	Oryctolagus cuniculus	95.70	0.00e+00	891.00
IUUC-Oba-075726	Oryza barthii	44.55	5.00e-85	307.00
IUUC-Obr-076286	Oryza brachyantha	46.88	1.00e-92	333.00
IUUC-Ogu-078473	Oryza glumaepatula	44.55	4.00e-85	308.00
IUUC-Oin-079393	Oryza indica	49.00	6.00e-98	350.00
IUUC-Olo-080446	Oryza longistaminata	46.15	9.00e-89	320.00
IUUC-Ome-081737	Oryza meridionalis	46.77	2.00e-88	319.00
IUUC-Oni-082853	Oryza nivara	44.55	5.00e-85	307.00
IUUC-Opu-083590	Oryza punctata	48.08	1.00e-97	349.00
IUUC-Oru-084184	Oryza rufipogon	44.55	5.00e-85	307.00
IUUC-Osa-085402	Oryza sativa	49.00	6.00e-98	350.00
IUUC-Ola-086615	Oryzias latipes	78.60	0.00e+00	715.00
IUUC-Olu-087738	Ostreococcus lucimarinus	49.14	7.00e-95	340.00
IUUC-Oga-088101	Otolemur garnettii	95.48	0.00e+00	889.00
IUUC-Oar-090293	Ovis aries	95.08	0.00e+00	886.00
IUUC-Ptr-090503	Pan troglodytes	95.48	0.00e+00	890.00
IUUC-Pan-092477	Papio anubis	93.03	0.00e+00	860.00
IUUC-Psi-093442	Pelodiscus sinensis	91.84	0.00e+00	857.00
IUUC-Pma-094247	Petromyzon marinus	80.86	0.00e+00	758.00
IUUC-Pno-094780	Phaeosphaeria nodorum	50.00	2.00e-115	408.00
IUUC-Ppa-095338	Physcomitrella patens	50.12	9.00e-117	413.00
IUUC-Pfo-097137	Poecilia formosa	86.49	0.00e+00	780.00
IUUC-Pab-098060	Pongo abelii	95.02	0.00e+00	852.00
IUUC-Pop-099470	Populus trichocarpa	46.92	1.00e-92	333.00
IUUC-Pca-100500	Procavia capensis	80.00	0.00e+00	723.00
IUUC-Ppe-102008	Prunus persica	47.59	1.00e-83	303.00
IUUC-Pva-103095	Pteropus vampyrus	96.67	2.00e-124	438.00
IUUC-Pgr-103666	Puccinia graminis	50.35	6.00e-114	404.00
IUUC-Ptt-103901	Puccinia triticina	51.29	5.00e-118	417.00
IUUC-Pte-104198	Pyrenophora teres	49.31	2.00e-119	422.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	48.62	2.00e-117	415.00
IUUC-Rno-105446	Rattus norvegicus	95.46	0.00e+00	887.00
IUUC-Sce-106355	Saccharomyces cerevisiae	42.68	4.00e-70	258.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	42.96	5.00e-97	347.00
IUUC-Spo-108345	Schizosaccharomyces pombe	42.31	3.00e-96	345.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	49.41	2.00e-107	382.00
IUUC-Smo-109133	Selaginella moellendorffii	48.82	3.00e-114	404.00
IUUC-Sit-109724	Setaria italica	48.51	4.00e-89	321.00
IUUC-Sly-110916	Solanum lycopersicum	48.33	1.00e-93	336.00
IUUC-Stu-112236	Solanum tuberosum	48.07	2.00e-93	335.00
IUUC-Sar-113044	Sorex araneus	95.02	0.00e+00	796.00
IUUC-Sbi-114276	Sorghum bicolor	48.64	3.00e-89	322.00
IUUC-Sre-114963	Sporisorium reilianum	52.21	2.00e-118	418.00
IUUC-Ssc-116301	Sus scrofa	94.85	0.00e+00	885.00
IUUC-Tgu-117265	Taeniopygia guttata	89.82	0.00e+00	850.00
IUUC-Tru-117526	Takifugu rubripes	84.30	0.00e+00	764.00
IUUC-Tsy-119483	Tarsius syrichta	94.93	0.00e+00	827.00
IUUC-Tni-120363	Tetraodon nigroviridis	86.65	0.00e+00	758.00
IUUC-Tca-121731	Theobroma cacao	48.86	6.00e-87	314.00
IUUC-Tre-122221	Trichoderma reesei	53.87	7.00e-112	396.00
IUUC-Tvi-122352	Trichoderma virens	52.21	9.00e-125	439.00
IUUC-Tae-123864	Triticum aestivum	47.12	1.00e-86	313.00
IUUC-Tur-126070	Triticum urartu	44.27	2.00e-67	249.00
IUUC-Tme-127199	Tuber melanosporum	50.65	2.00e-108	385.00
IUUC-Tbe-128076	Tupaia belangeri	95.02	0.00e+00	887.00
IUUC-Ttr-128695	Tursiops truncatus	79.86	0.00e+00	723.00
IUUC-Uma-129638	Ustilago maydis	51.52	4.00e-118	417.00
IUUC-Vda-129963	Verticillium dahliae	52.42	2.00e-115	409.00
IUUC-Vpa-130637	Vicugna pacos	88.24	0.00e+00	801.00
IUUC-Vvi-131613	Vitis vinifera	47.95	4.00e-83	301.00
IUUC-Xtr-132924	Xenopus tropicalis	90.52	0.00e+00	818.00
IUUC-Xma-133356	Xiphophorus maculatus	86.49	0.00e+00	780.00
IUUC-Yli-134365	Yarrowia lipolytica	52.43	2.00e-111	395.00
IUUC-Zma-135941	Zea mays	44.44	2.00e-84	306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence