iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067958

Ensembl Protein ID

ENSMLUP00000010110.2

UniProt Accession

G1PHG0; G1PHG0_MYOLU

Genbank Protein ID

ENSMLUP00000010110

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02048749

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000011064.2	ENSMLUT00000011093.2	ENSMLUP00000010110.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-09	38.2	708	752

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++CekC ++fH  C+ ++   ++p+ e wiC+ Cr
   Q: 708  DWCAVCQNGGE----LLCCEKCPKVFHLSCHVPT-LANFPSGE-WICTFCR 752
           79*********....*******************.*******8.******8 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

VGVIRCPVCS QECAERHIID NFFVKDTTEV PSSTVEKSNQ VCTSCEDNAE ANGFCVECVE 60
WLCKTCIRAH QRVKFTKDHT VRQKEEVSPE AVGVTSQRPV FCPFHKKEQL KLYCETCDKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGGAGTCA TTCGATGTCC AGTTTGTAGC CAAGAATGTG CAGAGCGACA CATCATCGAT 60
AATTTTTTTG TGAAGGATAC TACTGAGGTT CCCAGTAGTA CAGTAGAAAA ATCTAATCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	96.24	0.00e+00	1577.00
IUUC-Apl-003697	Anas platyrhynchos	79.36	0.00e+00	1317.00
IUUC-Bta-013282	Bos taurus	94.86	0.00e+00	1566.00
IUUC-Cja-018920	Callithrix jacchus	94.31	0.00e+00	1594.00
IUUC-Cfa-020984	Canis familiaris	96.03	0.00e+00	1585.00
IUUC-Cpo-022035	Cavia porcellus	93.23	0.00e+00	1618.00
IUUC-Csa-024208	Chlorocebus sabaeus	95.38	0.00e+00	1600.00
IUUC-Cho-024413	Choloepus hoffmanni	62.76	8.00e-160	557.00
IUUC-Dno-029145	Dasypus novemcinctus	94.95	0.00e+00	1642.00
IUUC-Dor-030396	Dipodomys ordii	92.36	0.00e+00	1249.00
IUUC-Ete-032414	Echinops telfairi	84.97	0.00e+00	904.00
IUUC-Eca-033489	Equus caballus	96.46	0.00e+00	1591.00
IUUC-Eeu-034654	Erinaceus europaeus	92.32	0.00e+00	764.00
IUUC-Fca-035844	Felis catus	92.39	0.00e+00	1464.00
IUUC-Fal-036735	Ficedula albicollis	79.98	0.00e+00	1335.00
IUUC-Gga-041124	Gallus gallus	78.50	0.00e+00	1297.00
IUUC-Ggo-044542	Gorilla gorilla	95.49	0.00e+00	1600.00
IUUC-Hsa-046785	Homo sapiens	95.38	0.00e+00	1598.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	95.38	0.00e+00	1590.00
IUUC-Laf-054279	Loxodonta africana	92.81	0.00e+00	1585.00
IUUC-Mcc-055668	Macaca mulatta	95.49	0.00e+00	1602.00
IUUC-Meu-056195	Macropus eugenii	76.04	0.00e+00	816.00
IUUC-Mga-059272	Meleagris gallopavo	79.57	0.00e+00	1298.00
IUUC-Mmr-060936	Microcebus murinus	94.74	0.00e+00	1585.00
IUUC-Mdo-062848	Monodelphis domestica	88.57	0.00e+00	1497.00
IUUC-Mmu-063598	Mus musculus	93.24	0.00e+00	1547.00
IUUC-Mpu-066272	Mustela putorius furo	95.70	0.00e+00	1573.00
IUUC-Nle-069375	Nomascus leucogenys	95.49	0.00e+00	1602.00
IUUC-Opr-070836	Ochotona princeps	78.19	0.00e+00	659.00
IUUC-Oan-073393	Ornithorhynchus anatinus	78.35	0.00e+00	1003.00
IUUC-Ocu-074873	Oryctolagus cuniculus	92.63	0.00e+00	1585.00
IUUC-Oga-088692	Otolemur garnettii	94.52	0.00e+00	1563.00
IUUC-Oar-090160	Ovis aries	95.60	0.00e+00	1578.00
IUUC-Ptr-090756	Pan troglodytes	95.38	0.00e+00	1598.00
IUUC-Pan-091719	Papio anubis	95.27	0.00e+00	1597.00
IUUC-Psi-093433	Pelodiscus sinensis	81.59	0.00e+00	1372.00
IUUC-Pma-094506	Petromyzon marinus	60.61	6.00e-51	192.00
IUUC-Pab-098599	Pongo abelii	93.98	0.00e+00	1570.00
IUUC-Pca-100540	Procavia capensis	85.94	0.00e+00	952.00
IUUC-Pva-102478	Pteropus vampyrus	89.26	0.00e+00	1421.00
IUUC-Rno-105478	Rattus norvegicus	76.47	0.00e+00	655.00
IUUC-Sha-106740	Sarcophilus harrisii	83.67	0.00e+00	1392.00
IUUC-Sar-113615	Sorex araneus	93.22	0.00e+00	1389.00
IUUC-Ssc-115513	Sus scrofa	94.68	6.00e-146	509.00
IUUC-Tgu-117368	Taeniopygia guttata	78.72	0.00e+00	1310.00
IUUC-Tsy-118904	Tarsius syrichta	95.05	0.00e+00	1598.00
IUUC-Tbe-127354	Tupaia belangeri	82.66	0.00e+00	712.00
IUUC-Ttr-128983	Tursiops truncatus	91.07	0.00e+00	1175.00
IUUC-Vpa-130420	Vicugna pacos	93.66	0.00e+00	1550.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence