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Tag Content
iUUCD ID IUUC-Xtr-132062
Ensembl Protein ID ENSXETP00000003881.3
UniProt Accession Q6NVL6; LDB1_XENTR
Genbank Protein ID AAH67989.1
Protein Name LIM domain-binding protein 1
Genbank Nucleotide ID BC067989
Gene Name ldb1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000001714.3 ENSXETT00000003881.3 ENSXETP00000003881.3
ENSXETG00000001714.3 ENSXETT00000003595.3 ENSXETP00000003595.3
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/U-box 65.20 1.00e-128 456.00 IUUC-Dme-031667
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Xenopus tropicalis
Functional Description
(View)

Functional Description


     Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. Acts as a coactivator together with otx2 to stimulate lhx1/lim1-mediated activation of the gsc promoter in the Spemann organizer. Acts synergistically with lhx1/lim1 and ssbp in axis formation (By similarity).
 Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. Acts as a coactivator together with otx2 to stimulate lhx1/lim1-mediated activation of the gsc promoter in the Spemann organizer. Acts synergistically with lhx1/lim1 and ssbp in axis formation (By similarity).
Protein Sequence
(Fasta)
MLDRDVGPTP MYPPTYLEPG IGRHTPYGNQ TDYRIFELNK RLQNWTEECD NLWWDAFTTE 60
FFEDDAMLTI TFCLEDGPKR YTIGRTLIPR YFRSIFEGGA TELYYVLKHP KESFHNNFVS 120
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Protein Fasta Sequence


>IUUC-Xtr-132062|E3,U-box|Xenopus tropicalis
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Nucleotide Sequence
(Fasta)
CAAGCCAGCA AGCCAGGAGC AGGCTGGCGG TTGCAGGAGC AGCCATTGTT GAGAAAGAAA 60
GGGGGAGAGA GAAAACCTTG CAAACAAAGA GAGAGAAAAA GAAAGGTCCT TCCTCCACCT 120
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Nucleotide Fasta Sequence


>IUUC-Xtr-132062|E3,U-box|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0539--Nucleus
KW-1185--Reference proteome
Interpro

IPR030167--LDB1
IPR029005--LIM-bd/SEUSS
Gene Ontology

GO:0005634--C:nucleus
GO:0030274--F:LIM domain binding
GO:0042803--F:protein homodimerization activity
GO:0000989--F:transcription factor activity, transcription factor binding
GO:0007275--P:multicellular organism development
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
KEGG xtr:407886
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000177 Aegilops tauschii 25.30 4.00e-04 40.40
IUUC-Aml-002031 Ailuropoda melanoleuca 97.87 0.00e+00 682.00
IUUC-Atr-003083 Amborella trichopoda 22.06 8.00e-04 39.70
IUUC-Apl-004210 Anas platyrhynchos 97.66 5.00e-160 556.00
IUUC-Aca-005241 Anolis carolinensis 98.93 0.00e+00 688.00
IUUC-Aly-006204 Arabidopsis lyrata 25.00 4.00e-06 47.00
IUUC-Ath-007339 Arabidopsis thaliana 25.00 3.00e-06 47.40
IUUC-Acl-008255 Aspergillus clavatus 20.18 2.00e-05 44.30
IUUC-Ame-010910 Astyanax mexicanus 95.73 0.00e+00 661.00
IUUC-Bgr-012180 Blumeria graminis 22.17 3.00e-05 43.90
IUUC-Bta-012596 Bos taurus 74.93 6.00e-157 546.00
IUUC-Bci-013927 Botrytis cinerea 24.66 4.00e-06 47.00
IUUC-Bol-015721 Brassica oleracea 25.53 8.00e-07 48.90
IUUC-Bra-017183 Brassica rapa 25.53 8.00e-07 48.90
IUUC-Cel-018189 Caenorhabditis elegans 33.62 6.00e-30 125.00
IUUC-Cja-019586 Callithrix jacchus 76.27 2.00e-158 551.00
IUUC-Cfa-021188 Canis familiaris 97.87 0.00e+00 680.00
IUUC-Cpo-022350 Cavia porcellus 97.33 0.00e+00 673.00
IUUC-Csa-023816 Chlorocebus sabaeus 97.60 0.00e+00 679.00
IUUC-Cho-024958 Choloepus hoffmanni 61.78 2.00e-65 242.00
IUUC-Cin-025721 Ciona intestinalis 49.37 1.00e-88 319.00
IUUC-Csv-026065 Ciona savignyi 51.57 8.00e-93 333.00
IUUC-Dre-027356 Danio rerio 70.97 9.00e-154 536.00
IUUC-Dno-029918 Dasypus novemcinctus 98.27 0.00e+00 662.00
IUUC-Dor-030634 Dipodomys ordii 97.87 0.00e+00 682.00
IUUC-Dse-031245 Dothistroma septosporum 24.00 2.00e-04 41.20
IUUC-Dme-031667 Drosophila melanogaster 63.74 2.00e-126 445.00
IUUC-Ete-032246 Echinops telfairi 73.67 5.00e-153 533.00
IUUC-Eca-034015 Equus caballus 75.42 2.00e-158 551.00
IUUC-Eeu-034902 Erinaceus europaeus 97.87 0.00e+00 682.00
IUUC-Fca-035903 Felis catus 97.35 0.00e+00 676.00
IUUC-Fal-037407 Ficedula albicollis 76.69 2.00e-155 541.00
IUUC-Gmo-039466 Gadus morhua 92.20 0.00e+00 691.00
IUUC-Ggr-040030 Gaeumannomyces graminis 25.93 7.00e-03 36.20
IUUC-Gga-040214 Gallus gallus 99.46 0.00e+00 693.00
IUUC-Gac-042214 Gasterosteus aculeatus 91.80 0.00e+00 695.00
IUUC-Gma-042794 Glycine max 24.53 8.00e-07 49.30
IUUC-Ggo-044988 Gorilla gorilla 75.42 3.00e-159 554.00
IUUC-Hsa-046092 Homo sapiens 76.12 3.00e-160 557.00
IUUC-Itr-047934 Ictidomys tridecemlineatus 97.87 0.00e+00 681.00
IUUC-Lch-049895 Latimeria chalumnae 80.65 1.00e-97 348.00
IUUC-Lpe-050806 Leersia perrieri 25.35 6.00e-06 46.20
IUUC-Loc-052845 Lepisosteus oculatus 96.27 0.00e+00 684.00
IUUC-Lma-053090 Leptosphaeria maculans 23.62 2.00e-04 41.20
IUUC-Laf-054538 Loxodonta africana 94.82 0.00e+00 630.00
IUUC-Mcc-055116 Macaca mulatta 81.55 2.00e-119 421.00
IUUC-Meu-056777 Macropus eugenii 92.27 0.00e+00 626.00
IUUC-Mpo-057376 Magnaporthe poae 21.99 3.00e-03 37.40
IUUC-Mtr-058142 Medicago truncatula 24.53 8.00e-07 49.30
IUUC-Mga-059716 Meleagris gallopavo 76.12 1.00e-154 538.00
IUUC-Mmr-060649 Microcebus murinus 75.14 1.00e-157 549.00
IUUC-Mdo-062535 Monodelphis domestica 75.70 7.00e-156 543.00
IUUC-Mmu-064036 Mus musculus 75.28 5.00e-160 556.00
IUUC-Mac-065338 Musa acuminata 23.67 1.00e-05 45.10
IUUC-Mpu-065719 Mustela putorius furo 97.87 0.00e+00 681.00
IUUC-Mlu-067219 Myotis lucifugus 96.02 0.00e+00 663.00
IUUC-Ncr-068691 Neurospora crassa 22.45 4.00e-04 40.40
IUUC-Nle-068983 Nomascus leucogenys 76.27 5.00e-159 553.00
IUUC-Opr-070467 Ochotona princeps 97.87 0.00e+00 682.00
IUUC-Ont-071566 Oreochromis niloticus 94.67 0.00e+00 700.00
IUUC-Oan-073368 Ornithorhynchus anatinus 97.33 0.00e+00 674.00
IUUC-Ocu-074854 Oryctolagus cuniculus 75.14 2.00e-159 555.00
IUUC-Ome-081687 Oryza meridionalis 26.32 2.00e-03 37.40
IUUC-Ola-086364 Oryzias latipes 94.93 0.00e+00 700.00
IUUC-Oga-088235 Otolemur garnettii 74.30 1.00e-154 538.00
IUUC-Oar-089547 Ovis aries 97.87 0.00e+00 682.00
IUUC-Ptr-091423 Pan troglodytes 75.70 1.00e-158 552.00
IUUC-Pan-092378 Papio anubis 97.60 0.00e+00 681.00
IUUC-Psi-093638 Pelodiscus sinensis 77.09 1.00e-153 535.00
IUUC-Pma-094384 Petromyzon marinus 65.34 2.00e-52 198.00
IUUC-Pno-095027 Phaeosphaeria nodorum 22.66 3.00e-04 40.40
IUUC-Pfo-096031 Poecilia formosa 92.00 0.00e+00 699.00
IUUC-Pab-097886 Pongo abelii 76.27 5.00e-159 553.00
IUUC-Pop-099430 Populus trichocarpa 24.85 5.00e-06 47.00
IUUC-Pca-101138 Procavia capensis 97.87 0.00e+00 682.00
IUUC-Ppe-101293 Prunus persica 29.67 2.00e-06 47.80
IUUC-Pva-103215 Pteropus vampyrus 75.42 4.00e-159 553.00
IUUC-Pte-104238 Pyrenophora teres 24.41 5.00e-04 39.30
IUUC-Rno-105968 Rattus norvegicus 75.56 3.00e-160 557.00
IUUC-Sha-107595 Sarcophilus harrisii 97.07 0.00e+00 668.00
IUUC-Ssl-108527 Sclerotinia sclerotiorum 23.45 3.00e-05 43.90
IUUC-Smo-109552 Selaginella moellendorffii 18.13 2.00e-03 38.10
IUUC-Sly-110873 Solanum lycopersicum 27.87 5.00e-06 46.60
IUUC-Stu-112586 Solanum tuberosum 20.00 6.00e-03 36.20
IUUC-Sar-113076 Sorex araneus 73.82 7.00e-104 370.00
IUUC-Sre-115143 Sporisorium reilianum 19.12 2.00e-03 37.70
IUUC-Ssc-115755 Sus scrofa 98.39 0.00e+00 688.00
IUUC-Tgu-117326 Taeniopygia guttata 76.40 1.00e-154 539.00
IUUC-Tru-117858 Takifugu rubripes 71.58 3.00e-157 547.00
IUUC-Tsy-119296 Tarsius syrichta 68.99 5.00e-139 487.00
IUUC-Tni-119822 Tetraodon nigroviridis 89.20 0.00e+00 637.00
IUUC-Tca-120935 Theobroma cacao 29.67 1.00e-06 48.90
IUUC-Tbe-127366 Tupaia belangeri 96.27 0.00e+00 657.00
IUUC-Ttr-128484 Tursiops truncatus 75.38 2.00e-147 514.00
IUUC-Vpa-130304 Vicugna pacos 73.21 1.00e-118 419.00
IUUC-Vvi-131560 Vitis vinifera 28.57 5.00e-06 47.00
IUUC-Xma-134288 Xiphophorus maculatus 94.93 0.00e+00 702.00
IUUC-Yli-134374 Yarrowia lipolytica 20.73 1.00e-05 44.70
IUUC-Zma-135310 Zea mays 23.16 2.00e-04 40.80
Created Date 25-Jun-2017

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