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Tag Content
UUCD2 ID IUUC-Pab-097816
UUCD1 version UUC-PoA-00905
Ensembl Protein ID ENSPPYP00000023154.2
UniProt Accession H2PWN2; H2PWN2_PONAB
Genbank Protein ID ENSPPYP00000023154
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABGA01094545
Gene Name CUL4B
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000020686.2 ENSPPYT00000024125.2 ENSPPYP00000023154.2
ENSPPYG00000020686.2 ENSPPYT00000024126.2 ENSPPYP00000023155.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 7.40e-190 632.8 210 668
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 24   tavynlclskvgaklYkklkevleefi.kqvkkkveesedeq.lLktynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLald 110
           +av+nlc++k++a+lYk+l++++e++i +q+++ +e+s d+  +Lk++ r+W+++++q+ ++r+if++ldrtyv +++++ ++++++l+
   Q: 210  EAVENLCSYKISANLYKQLRQICEDHIkAQIHQFREDSLDSVlFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLE 298
           689************************99************************************************************ PP
   S: 111  lwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleatqefykaesaeflqenevdeYl 197
           l+r +i++d  +++++++ +l lie+eR+gea+dr+ll+++ ++l++L     +iy++sFE++fle+t+++y+ae ++++qe+ev eYl
   Q: 299  LFRAHIISDqkVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDL-----QIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYL 382
           *********9**********************************9998.....9*********************************** PP
   S: 198  kkvearlneeeeraaryleestetkLlevvekeliakhlesll.aelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgk 285
           ++v++rl+ee +r+ +yl+++t+++L+++vek+l+ +hl+++l ++l++ll++++ +dls++y+L+srv+ g++ ll+++ ++ik  g+
   Q: 383  HHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILqKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFGS 471
           *****************************************9989******************************************** PP
   S: 286  aaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaaksp.EllAryiDqlLrksskglteeele 373
           ++++++ek+k+   +V++ll++k+k++++++ +F +++kF++a+++afetf+nk+     +++p El+A+y+D++Lr+++k++t+eele
   Q: 472  TIVINPEKDKT---MVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR-----PNKPaELIAKYVDSKLRAGNKEATDEELE 552
           ***********...*****************************************.....66666************************ PP
   S: 374  aqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeekenteese 462
           ++ldk++++f++i +kdvFe++Ykk+LakRLl+gksas +aE+s+++kLk+ecga+ftskLe+Mf+d+++S+d+++qFk+ ++n++   
   Q: 553  KMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPG 641
           ***************************************************************************************** PP
   S: 463  svelsvlvLsagaWptasetekvsLPae 490
           ++el+v++L++g+Wpt+  +e v+LP+e
   Q: 642  NIELTVNILTMGYWPTYVPME-VHLPPE 668
           *******************99.****98 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MMSQSSGSGD GSDDKAITSK DGGFSSPSPS AAAAAQEVRS ATDGNTSTTP PTSAKKRKLN 60
SSSSSSSNSS NEREDFDSTS SSSSTPPLQP RDSASPSTSS FCLGVSVAAS SHVPIQKKLR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-097816|E3,Cullin|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGATGTCAC AGTCATCTGG ATCAGGAGAT GGGAGTGATG ATAAGGCTAT TACCTCTAAA 60
GACGGTGGTG AGTAAATGAA CTAGTAAAAC TCAAGAGTTA AGTCTAAATA ATTGTTAACA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-097816|E3,Cullin|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031465--C:Cul4B-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005654--C:nucleoplasm
GO:0003684--F:damaged DNA binding
GO:0035518--P:histone H2A monoubiquitination
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0045732--P:positive regulation of protein catabolic process
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0070914--P:UV-damage excision repair
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002062 Ailuropoda melanoleuca 90.77 0.00e+00 1519.00
IUUC-Apl-004157 Anas platyrhynchos 85.45 0.00e+00 1332.00
IUUC-Aca-004430 Anolis carolinensis 83.58 0.00e+00 1277.00
IUUC-Bta-013244 Bos taurus 89.68 0.00e+00 1476.00
IUUC-Cja-019180 Callithrix jacchus 92.03 0.00e+00 1528.00
IUUC-Cfa-021189 Canis familiaris 91.39 0.00e+00 1524.00
IUUC-Cpo-021928 Cavia porcellus 90.47 0.00e+00 1485.00
IUUC-Csa-023831 Chlorocebus sabaeus 91.43 0.00e+00 1530.00
IUUC-Cho-024959 Choloepus hoffmanni 91.03 0.00e+00 936.00
IUUC-Dre-027916 Danio rerio 80.42 0.00e+00 1243.00
IUUC-Dno-029483 Dasypus novemcinctus 81.28 0.00e+00 1345.00
IUUC-Ete-032775 Echinops telfairi 79.32 0.00e+00 1211.00
IUUC-Eca-033952 Equus caballus 88.48 0.00e+00 1464.00
IUUC-Eeu-034767 Erinaceus europaeus 88.55 0.00e+00 1390.00
IUUC-Fca-036211 Felis catus 89.51 0.00e+00 1338.00
IUUC-Fal-037248 Ficedula albicollis 86.12 0.00e+00 1334.00
IUUC-Gga-041002 Gallus gallus 82.46 0.00e+00 1339.00
IUUC-Ggo-045468 Gorilla gorilla 91.61 0.00e+00 1478.00
IUUC-Hsa-046848 Homo sapiens 92.00 0.00e+00 1546.00
IUUC-Itr-048365 Ictidomys tridecemlineatus 89.57 0.00e+00 1486.00
IUUC-Lch-049858 Latimeria chalumnae 78.47 0.00e+00 1310.00
IUUC-Loc-052415 Lepisosteus oculatus 77.30 0.00e+00 1259.00
IUUC-Laf-053701 Loxodonta africana 89.90 0.00e+00 1497.00
IUUC-Mcc-055538 Macaca mulatta 90.03 0.00e+00 1496.00
IUUC-Mga-059754 Meleagris gallopavo 82.27 0.00e+00 1332.00
IUUC-Mmr-060870 Microcebus murinus 90.21 0.00e+00 1502.00
IUUC-Mdo-062015 Monodelphis domestica 83.27 0.00e+00 1303.00
IUUC-Mmu-063751 Mus musculus 88.91 0.00e+00 1442.00
IUUC-Mpu-065903 Mustela putorius furo 90.77 0.00e+00 1524.00
IUUC-Mlu-068213 Myotis lucifugus 90.47 0.00e+00 1497.00
IUUC-Nle-069480 Nomascus leucogenys 91.43 0.00e+00 1530.00
IUUC-Opr-071164 Ochotona princeps 83.79 9.00e-159 553.00
IUUC-Oan-073607 Ornithorhynchus anatinus 85.91 0.00e+00 1311.00
IUUC-Ocu-074446 Oryctolagus cuniculus 90.99 0.00e+00 1520.00
IUUC-Oga-088416 Otolemur garnettii 88.95 0.00e+00 1420.00
IUUC-Oar-090230 Ovis aries 90.37 0.00e+00 1474.00
IUUC-Ptr-091153 Pan troglodytes 91.69 0.00e+00 1485.00
IUUC-Pan-091729 Papio anubis 91.43 0.00e+00 1530.00
IUUC-Psi-093773 Pelodiscus sinensis 85.59 0.00e+00 1326.00
IUUC-Pfo-096828 Poecilia formosa 80.50 0.00e+00 1247.00
IUUC-Pca-100858 Procavia capensis 78.59 0.00e+00 1241.00
IUUC-Pva-102995 Pteropus vampyrus 84.49 0.00e+00 1393.00
IUUC-Rno-106119 Rattus norvegicus 89.60 0.00e+00 1455.00
IUUC-Sha-106958 Sarcophilus harrisii 79.93 0.00e+00 1318.00
IUUC-Sar-113581 Sorex araneus 84.88 0.00e+00 898.00
IUUC-Tgu-116462 Taeniopygia guttata 85.75 0.00e+00 1323.00
IUUC-Tru-118299 Takifugu rubripes 79.97 0.00e+00 1241.00
IUUC-Tni-120811 Tetraodon nigroviridis 78.78 0.00e+00 1224.00
IUUC-Tbe-127658 Tupaia belangeri 88.42 0.00e+00 1417.00
IUUC-Ttr-129112 Tursiops truncatus 82.61 0.00e+00 1321.00
IUUC-Vpa-130217 Vicugna pacos 83.37 0.00e+00 1352.00
IUUC-Xtr-132724 Xenopus tropicalis 83.40 0.00e+00 1287.00
Created Date 25-Jun-2017

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