iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093558

Ensembl Protein ID

ENSPSIP00000019027.1

UniProt Accession

K7GFG6; K7GFG6_PELSI

Genbank Protein ID

ENSPSIP00000019027

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01153149

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000016848.1	ENSPSIT00000019114.1	ENSPSIP00000019027.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	60.49	2.00e-155	546.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MTSSTSDQYP ASESACRITL GQANQVRPKL PLLKILQAAG AQGETFTLKE VMCYLGQYII 60
ARQLYDKRQQ HMVYCGGDQL GELLGLENFS VKDPSPVYDM LKRNLTSVTI TDAAQTLALA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTGCACTGT GGCTGTGAGG GTACACATTC ATGTGCACAC TGGGGGTGCA TTACTTTGCT 60
CTGTGGCACA TTGGGGGTGC ATTACTTTGC ACTGGGGTCC CACATCCCTG TGCACACTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR001370--BIR_rpt
IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF02201--SWIB

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	63.21	1.00e-154	539.00
IUUC-Apl-003800	Anas platyrhynchos	76.36	0.00e+00	671.00
IUUC-Aca-004608	Anolis carolinensis	64.52	2.00e-163	568.00
IUUC-Ame-010869	Astyanax mexicanus	46.99	1.00e-112	399.00
IUUC-Bta-013287	Bos taurus	60.90	2.00e-165	575.00
IUUC-Cja-019305	Callithrix jacchus	60.90	2.00e-150	525.00
IUUC-Cfa-020393	Canis familiaris	61.99	5.00e-162	563.00
IUUC-Cpo-022166	Cavia porcellus	60.30	4.00e-148	517.00
IUUC-Csa-023654	Chlorocebus sabaeus	63.75	2.00e-154	538.00
IUUC-Cho-024403	Choloepus hoffmanni	60.67	2.00e-78	285.00
IUUC-Cin-025448	Ciona intestinalis	27.10	1.00e-17	82.80
IUUC-Dre-027754	Danio rerio	46.55	1.00e-121	429.00
IUUC-Dno-029630	Dasypus novemcinctus	62.53	4.00e-166	577.00
IUUC-Dor-031064	Dipodomys ordii	48.57	9.00e-122	429.00
IUUC-Ete-032901	Echinops telfairi	56.21	1.00e-151	529.00
IUUC-Eca-034234	Equus caballus	64.15	1.00e-178	618.00
IUUC-Eeu-035015	Erinaceus europaeus	54.26	4.00e-54	205.00
IUUC-Fca-036587	Felis catus	61.71	7.00e-162	563.00
IUUC-Fal-036906	Ficedula albicollis	68.49	7.00e-178	616.00
IUUC-Gmo-038646	Gadus morhua	46.79	2.00e-110	392.00
IUUC-Gga-040124	Gallus gallus	76.36	3.00e-145	507.00
IUUC-Gac-042397	Gasterosteus aculeatus	45.82	4.00e-112	397.00
IUUC-Ggo-045505	Gorilla gorilla	63.34	8.00e-156	543.00
IUUC-Hsa-046950	Homo sapiens	63.54	2.00e-156	545.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	61.71	1.00e-159	555.00
IUUC-Lch-050141	Latimeria chalumnae	55.40	4.00e-137	481.00
IUUC-Loc-051921	Lepisosteus oculatus	49.80	5.00e-122	431.00
IUUC-Laf-054281	Loxodonta africana	59.06	3.00e-155	541.00
IUUC-Mcc-055462	Macaca mulatta	58.54	1.00e-139	489.00
IUUC-Meu-056294	Macropus eugenii	66.22	9.00e-131	459.00
IUUC-Mga-059924	Meleagris gallopavo	75.31	0.00e+00	702.00
IUUC-Mmr-061428	Microcebus murinus	61.71	1.00e-168	586.00
IUUC-Mdo-062643	Monodelphis domestica	65.72	4.00e-174	603.00
IUUC-Mmu-063229	Mus musculus	62.04	3.00e-155	541.00
IUUC-Mpu-065782	Mustela putorius furo	63.29	3.00e-157	547.00
IUUC-Mlu-068105	Myotis lucifugus	56.97	1.00e-150	525.00
IUUC-Nle-069549	Nomascus leucogenys	63.54	2.00e-156	545.00
IUUC-Opr-070568	Ochotona princeps	61.51	5.00e-156	543.00
IUUC-Ont-072276	Oreochromis niloticus	46.11	2.00e-118	419.00
IUUC-Oan-072787	Ornithorhynchus anatinus	65.24	6.00e-160	556.00
IUUC-Ocu-074912	Oryctolagus cuniculus	62.93	7.00e-162	563.00
IUUC-Ola-087037	Oryzias latipes	45.67	7.00e-108	384.00
IUUC-Oga-088953	Otolemur garnettii	59.19	5.00e-149	520.00
IUUC-Oar-089202	Ovis aries	61.30	1.00e-168	585.00
IUUC-Ptr-090964	Pan troglodytes	63.54	8.00e-157	546.00
IUUC-Pan-091975	Papio anubis	63.54	3.00e-158	551.00
IUUC-Pfo-096454	Poecilia formosa	47.93	3.00e-120	425.00
IUUC-Pab-098123	Pongo abelii	63.54	4.00e-157	547.00
IUUC-Pca-101112	Procavia capensis	55.53	2.00e-144	504.00
IUUC-Pva-103098	Pteropus vampyrus	58.32	4.00e-149	521.00
IUUC-Rno-105930	Rattus norvegicus	62.53	7.00e-153	533.00
IUUC-Sha-107512	Sarcophilus harrisii	63.73	6.00e-158	550.00
IUUC-Sar-113584	Sorex araneus	56.12	8.00e-141	493.00
IUUC-Tgu-116766	Taeniopygia guttata	72.49	2.00e-124	438.00
IUUC-Tru-117829	Takifugu rubripes	47.97	1.00e-116	413.00
IUUC-Tsy-119268	Tarsius syrichta	56.12	4.00e-63	234.00
IUUC-Tni-120204	Tetraodon nigroviridis	46.30	1.00e-111	396.00
IUUC-Tbe-127840	Tupaia belangeri	62.09	8.00e-84	303.00
IUUC-Ttr-128863	Tursiops truncatus	61.35	3.00e-158	551.00
IUUC-Vpa-130718	Vicugna pacos	60.86	8.00e-156	543.00
IUUC-Xtr-132320	Xenopus tropicalis	49.77	6.00e-104	370.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence