iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-072951

Ensembl Protein ID

ENSOANP00000010311.1

UniProt Accession

F6R4G0; F6R4G0_ORNAN

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006459.2	ENSOANT00000010313.2	ENSOANP00000010311.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.40e-06	26.8	167	206

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ + f   ++ +ll+s s+D+++++W++++g+ l+
   Q: 167  GHTEFVSRI-FvvpNCpDLLLSTSGDCSLRLWEYTSGRELQ 206
           677878888.88965589*******************9886 PP

Organism

Ornithorhynchus anatinus

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

LIAPFISSSD DVCFFVYDCT TAEKKPPEDK GEDEQPVDTG SDNILASTFS KSGNFFALTD 60
DNKRLILFRT QPSWECLSVR AVVRRCTSLT FTTSEEKILV ADKSGDVYSF SVMEPHSGGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAACAGGGCA TTTTTCAGTG CCAAAAAGCA GCCTCCCTGT TTGGCAGCAC CCCTCTTTAA 60
TCGCTCCATT CATTTCTTCT AGTGATGACG TCTGCTTCTT TGTCTACGAC TGCACCACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0043527--C:tRNA methyltransferase complex
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	27.08	5.00e-12	64.70
IUUC-Apl-003975	Anas platyrhynchos	61.08	5.00e-131	459.00
IUUC-Aca-005170	Anolis carolinensis	60.53	1.00e-118	419.00
IUUC-Aly-005769	Arabidopsis lyrata	29.41	1.00e-25	110.00
IUUC-Ath-006733	Arabidopsis thaliana	29.67	2.00e-24	106.00
IUUC-Acl-008151	Aspergillus clavatus	28.68	5.00e-17	82.00
IUUC-Afl-008518	Aspergillus flavus	27.56	2.00e-18	85.90
IUUC-Afu-009102	Aspergillus fumigatus	31.45	2.00e-17	83.20
IUUC-Ani-009442	Aspergillus nidulans	30.20	8.00e-17	81.30
IUUC-Aor-010133	Aspergillus oryzae	28.12	3.00e-23	102.00
IUUC-Ate-010465	Aspergillus terreus	42.55	3.00e-15	75.90
IUUC-Ame-010613	Astyanax mexicanus	46.72	8.00e-93	333.00
IUUC-Bgr-012067	Blumeria graminis	38.67	4.00e-21	95.10
IUUC-Bta-012788	Bos taurus	68.30	1.00e-148	518.00
IUUC-Bdi-014458	Brachypodium distachyon	30.52	5.00e-18	85.10
IUUC-Bol-015373	Brassica oleracea	36.14	1.00e-26	115.00
IUUC-Bra-016644	Brassica rapa	37.36	3.00e-25	110.00
IUUC-Cpo-021963	Cavia porcellus	65.08	4.00e-136	477.00
IUUC-Csa-024148	Chlorocebus sabaeus	68.62	1.00e-131	462.00
IUUC-Cne-026834	Cryptococcus neoformans	36.99	3.00e-20	92.40
IUUC-Dre-028427	Danio rerio	48.95	2.00e-98	351.00
IUUC-Dno-028881	Dasypus novemcinctus	58.99	4.00e-133	467.00
IUUC-Dor-030522	Dipodomys ordii	64.31	2.00e-142	498.00
IUUC-Dme-032136	Drosophila melanogaster	37.84	1.00e-25	110.00
IUUC-Fca-035833	Felis catus	65.71	7.00e-146	509.00
IUUC-Fal-037497	Ficedula albicollis	61.89	7.00e-132	462.00
IUUC-Gga-040547	Gallus gallus	60.37	9.00e-135	472.00
IUUC-Gac-041761	Gasterosteus aculeatus	46.38	1.00e-84	306.00
IUUC-Gma-043722	Glycine max	29.26	2.00e-22	99.40
IUUC-Ggo-045340	Gorilla gorilla	67.61	3.00e-140	491.00
IUUC-Hsa-046403	Homo sapiens	67.35	1.00e-139	488.00
IUUC-Hvu-047643	Hordeum vulgare	30.28	5.00e-20	91.30
IUUC-Itr-048103	Ictidomys tridecemlineatus	67.90	5.00e-148	516.00
IUUC-Kpa-049283	Komagataella pastoris	34.69	3.00e-19	89.00
IUUC-Lch-050682	Latimeria chalumnae	54.76	5.00e-117	413.00
IUUC-Lpe-050712	Leersia perrieri	33.47	2.00e-27	116.00
IUUC-Loc-052599	Lepisosteus oculatus	54.72	2.00e-115	408.00
IUUC-Laf-054390	Loxodonta africana	68.12	7.00e-152	529.00
IUUC-Mcc-054747	Macaca mulatta	68.09	9.00e-137	479.00
IUUC-Mtr-058600	Medicago truncatula	31.69	9.00e-26	110.00
IUUC-Mla-059129	Melampsora laricipopulina	26.74	1.00e-14	73.20
IUUC-Mga-059876	Meleagris gallopavo	60.37	2.00e-133	468.00
IUUC-Mvi-060359	Microbotryum violaceum	31.18	7.00e-14	71.60
IUUC-Mmr-061518	Microcebus murinus	63.75	1.00e-137	482.00
IUUC-Mac-065625	Musa acuminata	33.86	2.00e-21	96.30
IUUC-Nfi-068402	Neosartorya fischeri	30.43	3.00e-15	76.30
IUUC-Nle-069914	Nomascus leucogenys	67.02	1.00e-132	465.00
IUUC-Ont-071555	Oreochromis niloticus	42.78	4.00e-78	284.00
IUUC-Ocu-074679	Oryctolagus cuniculus	64.49	2.00e-131	461.00
IUUC-Oba-075355	Oryza barthii	26.80	6.00e-12	65.10
IUUC-Obr-076769	Oryza brachyantha	31.60	6.00e-25	107.00
IUUC-Ogl-077168	Oryza glaberrima	32.13	2.00e-24	105.00
IUUC-Ogu-078275	Oryza glumaepatula	26.40	3.00e-12	65.90
IUUC-Oin-079207	Oryza indica	32.13	2.00e-24	105.00
IUUC-Oni-082437	Oryza nivara	27.67	5.00e-12	65.10
IUUC-Opu-084031	Oryza punctata	31.89	4.00e-23	102.00
IUUC-Oru-084380	Oryza rufipogon	26.51	1.00e-11	63.90
IUUC-Osa-085327	Oryza sativa	32.14	7.00e-24	104.00
IUUC-Ola-086716	Oryzias latipes	42.62	7.00e-76	276.00
IUUC-Olu-087708	Ostreococcus lucimarinus	31.16	4.00e-17	81.60
IUUC-Oar-090239	Ovis aries	69.10	1.00e-142	498.00
IUUC-Ptr-090851	Pan troglodytes	67.61	1.00e-140	492.00
IUUC-Pan-092558	Papio anubis	68.78	1.00e-131	462.00
IUUC-Psi-093792	Pelodiscus sinensis	66.67	1.00e-142	498.00
IUUC-Ppa-095757	Physcomitrella patens	37.21	2.00e-21	96.30
IUUC-Pfo-096465	Poecilia formosa	43.02	2.00e-84	305.00
IUUC-Pab-097722	Pongo abelii	68.35	8.00e-143	499.00
IUUC-Pop-098979	Populus trichocarpa	32.62	5.00e-20	91.70
IUUC-Pca-100753	Procavia capensis	69.12	1.00e-110	392.00
IUUC-Ppe-101515	Prunus persica	29.58	3.00e-20	92.40
IUUC-Sja-107780	Schizosaccharomyces japonicus	29.65	3.00e-15	75.90
IUUC-Spo-108251	Schizosaccharomyces pombe	30.49	2.00e-14	72.80
IUUC-Smo-108938	Selaginella moellendorffii	33.80	9.00e-23	100.00
IUUC-Sit-110020	Setaria italica	30.71	4.00e-22	98.60
IUUC-Sly-111543	Solanum lycopersicum	28.69	8.00e-24	104.00
IUUC-Stu-111925	Solanum tuberosum	29.25	2.00e-24	105.00
IUUC-Sbi-114061	Sorghum bicolor	31.13	6.00e-24	104.00
IUUC-Tgu-117321	Taeniopygia guttata	61.70	6.00e-122	429.00
IUUC-Tru-118454	Takifugu rubripes	44.02	2.00e-79	288.00
IUUC-Tni-119894	Tetraodon nigroviridis	42.41	2.00e-75	275.00
IUUC-Tca-121746	Theobroma cacao	32.67	2.00e-21	95.90
IUUC-Tae-124114	Triticum aestivum	30.86	1.00e-20	94.00
IUUC-Tur-126254	Triticum urartu	25.40	6.00e-12	64.30
IUUC-Tbe-127683	Tupaia belangeri	40.36	2.00e-39	155.00
IUUC-Ttr-129056	Tursiops truncatus	65.16	3.00e-135	474.00
IUUC-Vvi-131428	Vitis vinifera	34.22	1.00e-21	97.10
IUUC-Xma-133605	Xiphophorus maculatus	43.41	4.00e-85	307.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence