iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116511

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01016981

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000007496.1	ENSTGUT00000007804.1	ENSTGUP00000007723.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.30e-90	303.0	4	337

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenp..kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+Nl NtCYmN+vLQcL ++++l +++l+ k + +l+++++   +  ge ++++  l++ +w +k  +vsp+++ ++++k  + fs 
   Q: 4    TGLQNLENTCYMNAVLQCLCSLTPLVQYFLSgKWNTDLHHSSQigHQLIGESATAFGCLVSDMWLGKFDYVSPEAFHSVFGKRYPAFSR 92
           7******************************866666666654222334577888888888889************************* PP
   S: 87   yeqqDaqEflaflldqleeelkk...eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             q+DaqEfl ++ld+l+e++k+   +  +  +++  +++++++    +   ++++s+i++lF+gql+  i+cl+c++ s r e+f+ l
   Q: 93   RTQHDAQEFLICVLDDLHEAFKEvraQLPHLNDNAGPSQERQSPAAGASTRSSSGTSIITHLFEGQLSYGIRCLTCKTLSDRPESFTIL 181
           *********************88766556666666667777777888899999999********************************* PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+p+ + +   slqdcLe f+++++l+ +n++ c +c ++q+a+ k +++k P+++i+hLkRf ++   k+r+k+++ v +p + Ld
   Q: 182  SLPIPSTRVC---SLQDCLECFFQPDTLTWNNQIRCHRCGSNQDATVKASITKAPQIIIFHLKRFAWQD--KHRRKLSTTVCYPFShLD 265
           ********99...****************************************************7755..6999*********999** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           lsp+ ++++ +   +++Y+L+avv+H G l+ GHY+a++k++  k W+ fdD++Vt+++ + v+    +taY+lfY +
   Q: 266  LSPYISTSCHN---TTEYSLCAVVNHAGDLDYGHYTAFCKHSITKhWYSFDDDQVTKIPDSAVQA---DTAYLLFYIS 337
           *******8866...89*************************65556*******************...********75 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

PGLTGLQNLE NTCYMNAVLQ CLCSLTPLVQ YFLSGKWNTD LHHSSQIGHQ LIGESATAFG 60
CLVSDMWLGK FDYVSPEAFH SVFGKRYPAF SRRTQHDAQE FLICVLDDLH EAFKEVRAQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGACTGA CGGGGCTGCA GAACCTGGAG AACACGTGCT ACATGAACGC GGTGCTGCAG 60
TGCCTCTGCA GCCTGACCCC GCTCGTGCAG TATTTCCTCT CAGGGAAGTG GAACACAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	54.90	2.00e-101	362.00
IUUC-Bta-012753	Bos taurus	52.82	4.00e-95	340.00
IUUC-Cfa-020054	Canis familiaris	54.90	7.00e-93	333.00
IUUC-Cpo-021375	Cavia porcellus	54.63	1.00e-99	355.00
IUUC-Cho-024755	Choloepus hoffmanni	48.70	6.00e-77	280.00
IUUC-Ete-032570	Echinops telfairi	42.11	3.00e-53	201.00
IUUC-Eca-034343	Equus caballus	55.49	3.00e-104	370.00
IUUC-Eeu-034510	Erinaceus europaeus	55.27	6.00e-93	333.00
IUUC-Fca-035920	Felis catus	55.19	4.00e-103	367.00
IUUC-Fal-036903	Ficedula albicollis	84.66	3.00e-167	580.00
IUUC-Hsa-046665	Homo sapiens	52.40	4.00e-88	317.00
IUUC-Itr-048167	Ictidomys tridecemlineatus	56.97	3.00e-107	381.00
IUUC-Lch-049925	Latimeria chalumnae	48.38	4.00e-89	320.00
IUUC-Loc-051880	Lepisosteus oculatus	42.60	1.00e-67	251.00
IUUC-Laf-054494	Loxodonta africana	56.97	5.00e-106	377.00
IUUC-Mcc-055507	Macaca mulatta	55.73	2.00e-99	355.00
IUUC-Meu-055906	Macropus eugenii	55.48	2.00e-91	328.00
IUUC-Mdo-061800	Monodelphis domestica	57.86	2.00e-108	384.00
IUUC-Mmu-063618	Mus musculus	56.51	1.00e-102	365.00
IUUC-Mpu-066699	Mustela putorius furo	54.90	3.00e-102	364.00
IUUC-Mlu-067672	Myotis lucifugus	54.97	9.00e-104	369.00
IUUC-Opr-070949	Ochotona princeps	55.09	3.00e-83	301.00
IUUC-Oan-073725	Ornithorhynchus anatinus	53.12	1.00e-99	355.00
IUUC-Ocu-074021	Oryctolagus cuniculus	56.68	3.00e-105	374.00
IUUC-Oga-088258	Otolemur garnettii	56.21	1.00e-94	338.00
IUUC-Oar-089881	Ovis aries	53.71	1.00e-100	358.00
IUUC-Ptr-090988	Pan troglodytes	51.13	4.00e-82	297.00
IUUC-Pan-091773	Papio anubis	55.85	7.00e-105	373.00
IUUC-Psi-093243	Pelodiscus sinensis	59.19	3.00e-106	377.00
IUUC-Pab-097713	Pongo abelii	55.52	5.00e-99	353.00
IUUC-Pca-100226	Procavia capensis	43.83	2.00e-65	242.00
IUUC-Pva-103172	Pteropus vampyrus	54.55	3.00e-92	331.00
IUUC-Rno-105950	Rattus norvegicus	56.08	5.00e-103	367.00
IUUC-Sha-107026	Sarcophilus harrisii	58.46	7.00e-108	383.00
IUUC-Ssc-116383	Sus scrofa	55.49	2.00e-103	368.00
IUUC-Tbe-127808	Tupaia belangeri	59.65	4.00e-35	141.00
IUUC-Ttr-129046	Tursiops truncatus	54.55	1.00e-90	326.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence