iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000002908.6	ENSGALT00000044729.2	ENSGALP00000042447.1
ENSGALG00000002908.6	ENSGALT00000004580.6	ENSGALP00000004571.4
ENSGALG00000002908.6	ENSGALT00000081625.1	ENSGALP00000056250.1
ENSGALG00000002908.6	ENSGALT00000088766.1	ENSGALP00000062781.1
ENSGALG00000002908.6	ENSGALT00000076163.1	ENSGALP00000046671.1
ENSGALG00000002908.6	ENSGALT00000087004.1	ENSGALP00000061479.1
ENSGALG00000002908.6	ENSGALT00000086242.1	ENSGALP00000060521.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-07	32.7	7	50

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC + f   +d +  +pCgH+fh+ Cl +w      + ++ +CP Cr
   Q: 7    CTICSDFFdnaRD-VAAVPCGHTFHRACLFQW----FDTAPSRTCPQCR 50
           9***888866344.999***************....99**********8 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MPIRAHCTIC SDFFDNARDV AAVPCGHTFH RACLFQWFDT APSRTCPQCR IQVSKRHIIS 60
KLFFDVALEE QTALDAETLQ PGSLLKQNQI SIQLLLLHWV SKLLSAVVWE CDFRAFAKTH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCCGTGAG GTCACTTCCG GCCTGAACCG GAAGTGGCGG CCGGGCGGCC GGGTTTGAAT 60
CGCGCGGCGC CGCGCGGCCT CAGCGCTGCC GGTCCCGCCA TGCCGATCCG CGCGCACTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0005057--F:signal transducer activity, downstream of receptor
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032688--P:negative regulation of interferon-beta production
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001411	Ailuropoda melanoleuca	53.28	4.00e-138	484.00
IUUC-Apl-003777	Anas platyrhynchos	81.77	3.00e-173	600.00
IUUC-Aca-004476	Anolis carolinensis	57.63	1.00e-156	545.00
IUUC-Ame-011706	Astyanax mexicanus	44.30	1.00e-08	50.80
IUUC-Bta-013084	Bos taurus	53.42	1.00e-141	496.00
IUUC-Bol-015240	Brassica oleracea	43.14	1.00e-09	56.60
IUUC-Cel-018227	Caenorhabditis elegans	39.06	4.00e-12	65.50
IUUC-Cja-019856	Callithrix jacchus	53.05	1.00e-143	502.00
IUUC-Cfa-020075	Canis familiaris	52.20	1.00e-143	502.00
IUUC-Cpo-022481	Cavia porcellus	52.67	3.00e-143	501.00
IUUC-Csa-023793	Chlorocebus sabaeus	53.79	5.00e-146	510.00
IUUC-Csv-026190	Ciona savignyi	29.83	2.00e-36	145.00
IUUC-Dre-027984	Danio rerio	47.78	4.00e-128	451.00
IUUC-Dno-029478	Dasypus novemcinctus	53.71	2.00e-145	508.00
IUUC-Dor-030526	Dipodomys ordii	39.31	5.00e-92	331.00
IUUC-Dme-032130	Drosophila melanogaster	24.41	4.00e-16	79.00
IUUC-Ete-033012	Echinops telfairi	60.12	2.00e-109	388.00
IUUC-Eca-034084	Equus caballus	54.30	2.00e-149	521.00
IUUC-Eeu-034579	Erinaceus europaeus	57.14	2.00e-97	349.00
IUUC-Fca-035772	Felis catus	53.54	2.00e-141	495.00
IUUC-Fal-037098	Ficedula albicollis	76.12	0.00e+00	686.00
IUUC-Gmo-038704	Gadus morhua	44.94	2.00e-114	405.00
IUUC-Gac-042636	Gasterosteus aculeatus	47.18	1.00e-122	432.00
IUUC-Ggo-045184	Gorilla gorilla	53.03	2.00e-142	498.00
IUUC-Hsa-046651	Homo sapiens	54.34	8.00e-141	493.00
IUUC-Itr-048550	Ictidomys tridecemlineatus	53.35	6.00e-148	516.00
IUUC-Lch-049575	Latimeria chalumnae	56.84	3.00e-152	531.00
IUUC-Loc-051999	Lepisosteus oculatus	48.67	5.00e-129	454.00
IUUC-Lma-053239	Leptosphaeria maculans	43.10	3.00e-08	53.50
IUUC-Laf-053347	Loxodonta africana	53.63	4.00e-148	517.00
IUUC-Mcc-054668	Macaca mulatta	47.52	3.00e-40	158.00
IUUC-Meu-056862	Macropus eugenii	48.77	6.00e-132	463.00
IUUC-Mga-059443	Meleagris gallopavo	82.53	0.00e+00	692.00
IUUC-Mmr-061219	Microcebus murinus	53.19	1.00e-146	512.00
IUUC-Mdo-062103	Monodelphis domestica	55.60	6.00e-157	546.00
IUUC-Mmu-064005	Mus musculus	52.01	9.00e-143	499.00
IUUC-Mpu-066570	Mustela putorius furo	53.54	5.00e-142	497.00
IUUC-Mlu-067806	Myotis lucifugus	53.92	5.00e-146	510.00
IUUC-Nle-069123	Nomascus leucogenys	53.03	6.00e-142	497.00
IUUC-Opr-071063	Ochotona princeps	52.19	5.00e-144	504.00
IUUC-Ont-071973	Oreochromis niloticus	45.78	5.00e-129	454.00
IUUC-Oan-073278	Ornithorhynchus anatinus	62.95	2.00e-92	332.00
IUUC-Ocu-074582	Oryctolagus cuniculus	50.58	5.00e-130	457.00
IUUC-Ola-086959	Oryzias latipes	45.30	7.00e-110	390.00
IUUC-Oga-088807	Otolemur garnettii	51.04	8.00e-133	466.00
IUUC-Oar-089273	Ovis aries	50.85	3.00e-133	468.00
IUUC-Ptr-090768	Pan troglodytes	53.03	1.00e-142	499.00
IUUC-Pan-091880	Papio anubis	53.63	2.00e-145	508.00
IUUC-Psi-093782	Pelodiscus sinensis	66.59	3.00e-167	581.00
IUUC-Pma-094365	Petromyzon marinus	36.83	8.00e-70	257.00
IUUC-Ppa-095896	Physcomitrella patens	34.52	4.00e-08	53.10
IUUC-Pfo-096068	Poecilia formosa	43.22	1.00e-108	386.00
IUUC-Pab-098063	Pongo abelii	51.42	6.00e-135	473.00
IUUC-Pca-100327	Procavia capensis	61.08	1.00e-129	455.00
IUUC-Pva-102924	Pteropus vampyrus	54.01	8.00e-145	506.00
IUUC-Pgr-103673	Puccinia graminis	44.64	8.00e-08	50.40
IUUC-Rno-105799	Rattus norvegicus	52.11	2.00e-144	505.00
IUUC-Sha-107643	Sarcophilus harrisii	52.75	1.00e-133	469.00
IUUC-Sar-113187	Sorex araneus	54.04	1.00e-135	476.00
IUUC-Ssc-115838	Sus scrofa	62.46	7.00e-108	383.00
IUUC-Tgu-116674	Taeniopygia guttata	76.43	0.00e+00	647.00
IUUC-Tru-117753	Takifugu rubripes	44.32	4.00e-120	424.00
IUUC-Tsy-119416	Tarsius syrichta	73.75	2.00e-33	136.00
IUUC-Tni-120767	Tetraodon nigroviridis	44.77	1.00e-118	419.00
IUUC-Tbe-128001	Tupaia belangeri	40.94	5.00e-46	178.00
IUUC-Ttr-128687	Tursiops truncatus	53.73	1.00e-145	509.00
IUUC-Xtr-131905	Xenopus tropicalis	53.70	7.00e-154	536.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence