iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067967

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02018294

Gene Name

RFWD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000023639.1	ENSMLUT00000023940.1	ENSMLUP00000022543.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.00e-20	70.6	334	363
E3 activity/RING/RING	2.20e-06	28.1	1	38

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 334  NSKISCISWssYHkNLLASSDYEGTVILWD 363
           689******9622599************** PP

E3 activity/RING/RING

   S: 2    aiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           +iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 1    PICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 38
           8******99.888***********9555......999999****6 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

PICFDMIEEA YMTKCGHSFC YKCIHQSLED NNRCPKCNYV VDNIDHLYPN FLVNELILKQ 60
KQRFEEKRFK LDHSVSSTNG HRWQIFQDLL GTDQDNLDLA NVNLMLELLV QKKKQLEAES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTATCTGCT TTGATATGAT CGAGGAAGCA TACATGACGA AATGTGGCCA CAGCTTTTGG 60
TAAGATGATT TTACTTAGCA AAATTGCCTT TTGGTATTCT TAAATCTGTG TGTAAATGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	39.33	1.00e-120	426.00
IUUC-Aml-001265	Ailuropoda melanoleuca	97.47	0.00e+00	1165.00
IUUC-Atr-002460	Amborella trichopoda	37.82	7.00e-116	411.00
IUUC-Apl-003796	Anas platyrhynchos	97.94	0.00e+00	1153.00
IUUC-Aca-005078	Anolis carolinensis	95.14	0.00e+00	1127.00
IUUC-Aly-006014	Arabidopsis lyrata	39.23	2.00e-121	429.00
IUUC-Ath-007636	Arabidopsis thaliana	39.29	7.00e-121	427.00
IUUC-Ame-011176	Astyanax mexicanus	94.31	3.00e-67	249.00
IUUC-Bta-012595	Bos taurus	97.15	0.00e+00	1167.00
IUUC-Bdi-014152	Brachypodium distachyon	38.62	3.00e-120	425.00
IUUC-Bol-016380	Brassica oleracea	39.87	2.00e-122	432.00
IUUC-Bra-017690	Brassica rapa	38.52	1.00e-116	414.00
IUUC-Cja-018926	Callithrix jacchus	96.82	0.00e+00	1161.00
IUUC-Cfa-021088	Canis familiaris	96.82	0.00e+00	1165.00
IUUC-Cpo-022442	Cavia porcellus	99.31	0.00e+00	1165.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	33.21	7.00e-32	130.00
IUUC-Csa-024119	Chlorocebus sabaeus	97.15	0.00e+00	1169.00
IUUC-Cho-024883	Choloepus hoffmanni	61.56	3.00e-96	346.00
IUUC-Cin-025375	Ciona intestinalis	55.67	0.00e+00	636.00
IUUC-Cme-027350	Cyanidioschyzon merolae	40.44	1.00e-73	271.00
IUUC-Dre-028453	Danio rerio	85.74	0.00e+00	1016.00
IUUC-Dno-029887	Dasypus novemcinctus	96.31	0.00e+00	1156.00
IUUC-Dor-031110	Dipodomys ordii	77.47	0.00e+00	891.00
IUUC-Ete-033016	Echinops telfairi	81.91	0.00e+00	951.00
IUUC-Eca-034403	Equus caballus	98.79	0.00e+00	1155.00
IUUC-Eeu-034690	Erinaceus europaeus	83.88	0.00e+00	954.00
IUUC-Fca-036475	Felis catus	98.96	0.00e+00	1155.00
IUUC-Fal-037189	Ficedula albicollis	95.98	0.00e+00	1157.00
IUUC-Gmo-039245	Gadus morhua	85.02	0.00e+00	1001.00
IUUC-Gga-040806	Gallus gallus	95.98	0.00e+00	1156.00
IUUC-Gac-042177	Gasterosteus aculeatus	86.00	0.00e+00	1033.00
IUUC-Gma-044187	Glycine max	39.52	3.00e-118	419.00
IUUC-Ggo-044430	Gorilla gorilla	97.99	0.00e+00	872.00
IUUC-Hsa-045853	Homo sapiens	96.82	0.00e+00	1161.00
IUUC-Hvu-047750	Hordeum vulgare	37.36	2.00e-86	314.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	99.17	3.00e-142	497.00
IUUC-Lch-050420	Latimeria chalumnae	89.57	0.00e+00	1066.00
IUUC-Lpe-051219	Leersia perrieri	38.66	7.00e-119	421.00
IUUC-Loc-052728	Lepisosteus oculatus	88.70	0.00e+00	1035.00
IUUC-Laf-053775	Loxodonta africana	96.46	0.00e+00	1164.00
IUUC-Meu-056595	Macropus eugenii	77.57	4.00e-176	611.00
IUUC-Mtr-058555	Medicago truncatula	40.10	4.00e-125	442.00
IUUC-Mga-059646	Meleagris gallopavo	97.77	0.00e+00	1149.00
IUUC-Mmr-060990	Microcebus murinus	96.98	0.00e+00	1171.00
IUUC-Mdo-062287	Monodelphis domestica	96.48	0.00e+00	1162.00
IUUC-Mmu-064097	Mus musculus	96.82	0.00e+00	1164.00
IUUC-Mac-065240	Musa acuminata	40.67	1.00e-126	446.00
IUUC-Mpu-066612	Mustela putorius furo	98.46	0.00e+00	1162.00
IUUC-Nle-069543	Nomascus leucogenys	96.98	0.00e+00	1165.00
IUUC-Opr-070366	Ochotona princeps	84.58	0.00e+00	676.00
IUUC-Ont-071522	Oreochromis niloticus	85.50	0.00e+00	1021.00
IUUC-Oan-073409	Ornithorhynchus anatinus	98.96	0.00e+00	1154.00
IUUC-Ocu-073756	Oryctolagus cuniculus	98.96	0.00e+00	1158.00
IUUC-Oba-075149	Oryza barthii	38.38	2.00e-118	421.00
IUUC-Obr-076563	Oryza brachyantha	38.50	1.00e-118	420.00
IUUC-Ogl-077701	Oryza glaberrima	38.38	1.00e-118	420.00
IUUC-Ogu-078383	Oryza glumaepatula	38.38	1.00e-118	420.00
IUUC-Oin-079965	Oryza indica	36.56	5.00e-107	381.00
IUUC-Olo-080639	Oryza longistaminata	38.22	2.00e-116	413.00
IUUC-Ome-081821	Oryza meridionalis	37.94	3.00e-108	386.00
IUUC-Oni-082622	Oryza nivara	38.38	1.00e-118	420.00
IUUC-Opu-083295	Oryza punctata	38.38	2.00e-118	419.00
IUUC-Oru-084661	Oryza rufipogon	38.38	1.00e-118	420.00
IUUC-Osa-085766	Oryza sativa	38.38	1.00e-118	420.00
IUUC-Ola-086727	Oryzias latipes	85.67	0.00e+00	1040.00
IUUC-Olu-087702	Ostreococcus lucimarinus	42.96	3.00e-64	238.00
IUUC-Oga-088215	Otolemur garnettii	99.48	0.00e+00	1160.00
IUUC-Oar-089880	Ovis aries	97.15	0.00e+00	1160.00
IUUC-Ptr-090597	Pan troglodytes	96.82	0.00e+00	1161.00
IUUC-Pan-091987	Papio anubis	97.15	0.00e+00	1167.00
IUUC-Psi-094033	Pelodiscus sinensis	95.44	0.00e+00	1135.00
IUUC-Pma-094587	Petromyzon marinus	70.28	0.00e+00	763.00
IUUC-Ppa-095256	Physcomitrella patens	38.84	5.00e-123	434.00
IUUC-Pfo-097388	Poecilia formosa	84.78	0.00e+00	1002.00
IUUC-Pab-098029	Pongo abelii	96.82	0.00e+00	1162.00
IUUC-Pop-099319	Populus trichocarpa	37.92	2.00e-121	429.00
IUUC-Pca-100846	Procavia capensis	88.27	0.00e+00	1055.00
IUUC-Ppe-101250	Prunus persica	37.99	2.00e-112	399.00
IUUC-Pva-102407	Pteropus vampyrus	96.82	0.00e+00	1152.00
IUUC-Rno-105312	Rattus norvegicus	96.82	0.00e+00	1162.00
IUUC-Sha-106514	Sarcophilus harrisii	98.40	0.00e+00	766.00
IUUC-Smo-109418	Selaginella moellendorffii	38.82	8.00e-121	427.00
IUUC-Sit-110248	Setaria italica	38.24	9.00e-120	424.00
IUUC-Sly-110964	Solanum lycopersicum	40.42	4.00e-125	441.00
IUUC-Stu-112882	Solanum tuberosum	40.42	5.00e-125	441.00
IUUC-Sar-113230	Sorex araneus	70.22	0.00e+00	775.00
IUUC-Sbi-113962	Sorghum bicolor	36.32	1.00e-114	407.00
IUUC-Ssc-115987	Sus scrofa	99.31	3.00e-161	561.00
IUUC-Tgu-116471	Taeniopygia guttata	95.64	0.00e+00	1154.00
IUUC-Tru-118231	Takifugu rubripes	84.97	0.00e+00	987.00
IUUC-Tsy-119415	Tarsius syrichta	96.15	0.00e+00	1140.00
IUUC-Tni-120893	Tetraodon nigroviridis	85.14	0.00e+00	994.00
IUUC-Tca-121703	Theobroma cacao	40.93	1.00e-122	433.00
IUUC-Tae-125317	Triticum aestivum	40.54	1.00e-125	443.00
IUUC-Tur-126557	Triticum urartu	40.23	7.00e-123	434.00
IUUC-Tbe-127253	Tupaia belangeri	68.01	0.00e+00	768.00
IUUC-Ttr-129100	Tursiops truncatus	94.81	0.00e+00	1108.00
IUUC-Vpa-130613	Vicugna pacos	90.12	0.00e+00	1065.00
IUUC-Vvi-130880	Vitis vinifera	40.57	3.00e-117	415.00
IUUC-Xtr-132033	Xenopus tropicalis	93.13	0.00e+00	1154.00
IUUC-Xma-133421	Xiphophorus maculatus	84.62	0.00e+00	1000.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence