iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118242

Ensembl Protein ID

ENSTRUP00000018483.1

UniProt Accession

H2T1E5; H2T1E5_TAKRU

Protein Name

Uncharacterized protein

Gene Name

kif21b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000007464.1	ENSTRUT00000018554.1	ENSTRUP00000018478.1
ENSTRUG00000007464.1	ENSTRUT00000018555.1	ENSTRUP00000018479.1
ENSTRUG00000007464.1	ENSTRUT00000018556.1	ENSTRUP00000018480.1
ENSTRUG00000007464.1	ENSTRUT00000018557.1	ENSTRUP00000018481.1
ENSTRUG00000007464.1	ENSTRUT00000018558.1	ENSTRUP00000018482.1
ENSTRUG00000007464.1	ENSTRUT00000018559.1	ENSTRUP00000018483.1
ENSTRUG00000007464.1	ENSTRUT00000018560.1	ENSTRUP00000018484.1
ENSTRUG00000007464.1	ENSTRUT00000018561.1	ENSTRUP00000018485.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.70e-27	93.3	1337	1370
UBD/Beta-Prp	7.10e-42	144.8	1332	1575

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           gH+ +v c++ +d ll +Gs D t+k+W+l tg 
   Q: 1337 GHSKPVLCVDATDELLFTGSKDRTCKMWNLVTGQ 1370
           8********9978*****************9996 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdle.tgqcle 130
           l+  +gh+++v +v+  ++  +l tgs+Drt k w+l tg+ ++tlkgh ++v+s++++ps+  l s s  ++i+vwd++ t +c++
   Q: 1332 LSVAEGHSKPVLCVDATDE--LLFTGSKDRTCKMWNLVTGQEIITLKGHPNNVVSVKYCPSSCLLFSVS-TSYIKVWDIRdTAKCVR 1415
           55569***********999..9**************************************776666666.89*******84667888 PP
   S: 131  e.....................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng...k 193
           +                     t+++ +  +n ++++p+g++l ++ + +tvr+Wdl++++ + +l g h +sv +l++ ++     
   Q: 1416 TftssgqvvsgdacagtttrtiTFAQGECQINQIALNPTGSVLYAA-AGNTVRMWDLNRMQGMGKLMG-HIGSVMCLTVGQSLlgkD 1500
           8*********************9***************99555443.3479****************9.*********888778889 PP
   S: 194  elvsgsldgtvklwdlqtgecvrtlnght......dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           ++++gs+d +vk++d+ +g+  +   +h+      d + ++ +   ++ l sgs D+ i+ Wdl++++l++++ + +
   Q: 1501 QVITGSKDHYVKVFDVAEGTLGNVGPAHNfepphyDGIECLSVQ--GDVLFSGSRDNGIKKWDLEQQELTQQIPNAH 1575
           9*******************988888888888888*********..************************9987765 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

RIRPQMAKEK IEGCHVCTLV APGEPQVLLG KDKAFTYDFV FDVDSEQQSI YQACVYKLIE 60
GCFEGYNATV FAYGQTGSGK TYTMGTGFDV SLGQQEQGII PRAVHQLFQG IQSSKVRAQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGAGGCC AGATGAAAGT AATTAACTTT AGTGAACTAC CTGTCAGAAA GTGAAGCCCG 60
GCAGACCTGT ACACATCAGG ATTAACTGCA GATACGAAAC AGCCTTTTAA AGTTTGACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	73.83	0.00e+00	1347.00
IUUC-Apl-003204	Anas platyrhynchos	73.06	0.00e+00	726.00
IUUC-Aca-004506	Anolis carolinensis	71.24	0.00e+00	2027.00
IUUC-Ame-011515	Astyanax mexicanus	78.30	0.00e+00	2486.00
IUUC-Bta-013185	Bos taurus	63.08	0.00e+00	662.00
IUUC-Cja-018844	Callithrix jacchus	74.28	0.00e+00	1395.00
IUUC-Cfa-021187	Canis familiaris	74.86	0.00e+00	1410.00
IUUC-Cpo-022444	Cavia porcellus	74.40	0.00e+00	1400.00
IUUC-Csa-023852	Chlorocebus sabaeus	74.40	0.00e+00	1402.00
IUUC-Csv-026158	Ciona savignyi	53.69	4.00e-174	605.00
IUUC-Dre-027839	Danio rerio	76.39	0.00e+00	2430.00
IUUC-Dno-030058	Dasypus novemcinctus	71.39	0.00e+00	1320.00
IUUC-Dor-030673	Dipodomys ordii	74.23	0.00e+00	1381.00
IUUC-Ete-032705	Echinops telfairi	67.52	0.00e+00	687.00
IUUC-Eca-033885	Equus caballus	73.46	0.00e+00	1353.00
IUUC-Eeu-035338	Erinaceus europaeus	73.99	0.00e+00	826.00
IUUC-Fca-035388	Felis catus	74.59	0.00e+00	1404.00
IUUC-Fal-037044	Ficedula albicollis	74.06	0.00e+00	1472.00
IUUC-Gmo-039034	Gadus morhua	76.95	0.00e+00	1488.00
IUUC-Gac-041328	Gasterosteus aculeatus	87.49	0.00e+00	2804.00
IUUC-Ggo-045392	Gorilla gorilla	73.78	0.00e+00	1387.00
IUUC-Hsa-046713	Homo sapiens	74.30	0.00e+00	1399.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	73.20	0.00e+00	1273.00
IUUC-Loc-052703	Lepisosteus oculatus	79.34	0.00e+00	2495.00
IUUC-Laf-054193	Loxodonta africana	67.53	0.00e+00	1254.00
IUUC-Mcc-055484	Macaca mulatta	73.03	0.00e+00	1390.00
IUUC-Meu-056278	Macropus eugenii	70.72	0.00e+00	993.00
IUUC-Mga-059816	Meleagris gallopavo	71.09	0.00e+00	2155.00
IUUC-Mmr-061071	Microcebus murinus	72.09	0.00e+00	1377.00
IUUC-Mdo-062845	Monodelphis domestica	74.40	0.00e+00	1400.00
IUUC-Mmu-063967	Mus musculus	74.23	0.00e+00	1374.00
IUUC-Mpu-066448	Mustela putorius furo	73.44	0.00e+00	1390.00
IUUC-Nle-070037	Nomascus leucogenys	73.44	0.00e+00	1410.00
IUUC-Opr-070325	Ochotona princeps	71.70	0.00e+00	1330.00
IUUC-Ont-071851	Oreochromis niloticus	88.80	0.00e+00	2836.00
IUUC-Oan-073615	Ornithorhynchus anatinus	75.02	0.00e+00	1417.00
IUUC-Ola-086703	Oryzias latipes	86.96	0.00e+00	2784.00
IUUC-Oga-088171	Otolemur garnettii	71.67	0.00e+00	1300.00
IUUC-Ptr-090535	Pan troglodytes	72.48	0.00e+00	1386.00
IUUC-Pan-091917	Papio anubis	73.09	0.00e+00	1196.00
IUUC-Pfo-096827	Poecilia formosa	82.29	0.00e+00	2615.00
IUUC-Pab-098441	Pongo abelii	74.30	0.00e+00	1400.00
IUUC-Pca-100781	Procavia capensis	78.46	0.00e+00	741.00
IUUC-Pva-103099	Pteropus vampyrus	70.32	0.00e+00	1015.00
IUUC-Rno-105872	Rattus norvegicus	73.95	0.00e+00	1395.00
IUUC-Sha-107097	Sarcophilus harrisii	73.28	0.00e+00	1329.00
IUUC-Ssc-115638	Sus scrofa	73.06	0.00e+00	1093.00
IUUC-Tni-119976	Tetraodon nigroviridis	96.56	0.00e+00	1208.00
IUUC-Ttr-128824	Tursiops truncatus	71.41	0.00e+00	1315.00
IUUC-Xtr-131798	Xenopus tropicalis	59.86	0.00e+00	1115.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence