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Tag Content
UUCD2 ID IUUC-Ptr-090758
UUCD1 version UUC-PaT-00162
Ensembl Protein ID ENSPTRP00000006096.5
UniProt Accession H2Q3F3; H2Q3F3_PANTR
Genbank Protein ID JAA06780.1; JAA21068.1; JAA25805.1; JAA41194.1
Protein Name TNF receptor-associated factor 6
Genbank Nucleotide ID AACZ03078427; GABF01001077; GABD01007295; GABE01003545
Gene Name TRAF6
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPTRG00000003510.5 ENSPTRT00000006610.5 ENSPTRP00000006096.5
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 3.60e-07 30.1 66 127
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrli 65
    + + CpI l r+ v +p+G+ + +++I k +++ g++cPv+++ l e++l P ++ +r i
   Q: 66 SKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREI 127
    5689*****************************999999*****************999977 PP
   

Organism Pan troglodytes
Protein Sequence
(Fasta)
MSLLNCENSC GSSQSESDCC VAMASSCSAA TKDDSVGGTA STGNLSSSFM EEIQGYDVEF 60
DPPLESKYEC PICLMALREA VQTPCGHRFC KACIIKSIRD AGHKCPVDNE ILLENQLFPD 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Ptr-090758|E3,U-box|Pan troglodytes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCAGAGAAG GCGGAAGCAG TGGCGTCCGC AGCTGGGGCT TGGCCTGCGG GCGGCCAGCG 60
AAGGTGGCGA AGGCTCCCAC TGGATCCAGA GTTTGCCGTC CAAGCAGCCT CGTCTCGGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Ptr-090758|E3,U-box|Pan troglodytes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0675--Receptor
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027139--TRAF6
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:0005811--C:lipid particle
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0043234--C:protein complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0019886--P:antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0045453--P:bone resorption
GO:0048468--P:cell development
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:0043011--P:myeloid dendritic cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0001843--P:neural tube closure
GO:0042475--P:odontogenesis of dentin-containing tooth
GO:0001503--P:ossification
GO:0030316--P:osteoclast differentiation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045084--P:positive regulation of interleukin-12 biosynthetic process
GO:0032743--P:positive regulation of interleukin-2 production
GO:0045410--P:positive regulation of interleukin-6 biosynthetic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0031666--P:positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045672--P:positive regulation of osteoclast differentiation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0042102--P:positive regulation of T cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051023--P:regulation of immunoglobulin secretion
GO:0050852--P:T cell receptor signaling pathway
GO:0042088--P:T-helper 1 type immune response

KEGG ptr:451702
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001262 Ailuropoda melanoleuca 90.94 0.00e+00 954.00
IUUC-Apl-004062 Anas platyrhynchos 72.41 0.00e+00 830.00
IUUC-Aca-004636 Anolis carolinensis 70.80 0.00e+00 771.00
IUUC-Ame-011682 Astyanax mexicanus 52.23 9.00e-162 563.00
IUUC-Bta-012692 Bos taurus 89.30 0.00e+00 977.00
IUUC-Bci-013998 Botrytis cinerea 24.60 4.00e-14 72.80
IUUC-Cja-019426 Callithrix jacchus 95.03 0.00e+00 1004.00
IUUC-Cfa-020948 Canis familiaris 89.78 0.00e+00 840.00
IUUC-Cpo-021378 Cavia porcellus 88.95 0.00e+00 946.00
IUUC-Csa-024045 Chlorocebus sabaeus 98.85 0.00e+00 1053.00
IUUC-Cho-024973 Choloepus hoffmanni 76.19 5.00e-107 381.00
IUUC-Csv-026300 Ciona savignyi 39.53 8.00e-47 179.00
IUUC-Dre-027557 Danio rerio 56.72 2.00e-176 612.00
IUUC-Dno-030032 Dasypus novemcinctus 84.71 2.00e-143 501.00
IUUC-Dor-030790 Dipodomys ordii 92.40 0.00e+00 981.00
IUUC-Dme-031921 Drosophila melanogaster 26.62 1.00e-38 154.00
IUUC-Ete-032952 Echinops telfairi 89.06 5.00e-171 593.00
IUUC-Eca-033924 Equus caballus 84.90 0.00e+00 867.00
IUUC-Eeu-034734 Erinaceus europaeus 86.42 0.00e+00 886.00
IUUC-Fca-036222 Felis catus 82.84 0.00e+00 838.00
IUUC-Fal-036834 Ficedula albicollis 73.46 0.00e+00 733.00
IUUC-Fox-037935 Fusarium oxysporum 29.44 4.00e-21 96.30
IUUC-Gmo-039061 Gadus morhua 57.65 2.00e-89 322.00
IUUC-Ggr-040084 Gaeumannomyces graminis 28.38 4.00e-13 69.30
IUUC-Gga-040599 Gallus gallus 72.84 0.00e+00 836.00
IUUC-Gac-041977 Gasterosteus aculeatus 55.66 9.00e-167 580.00
IUUC-Ggo-044508 Gorilla gorilla 91.41 0.00e+00 945.00
IUUC-Hsa-046349 Homo sapiens 99.62 0.00e+00 1090.00
IUUC-Itr-047966 Ictidomys tridecemlineatus 92.26 0.00e+00 991.00
IUUC-Lch-049821 Latimeria chalumnae 67.26 0.00e+00 754.00
IUUC-Lpe-051025 Leersia perrieri 25.29 3.00e-06 45.80
IUUC-Loc-051995 Lepisosteus oculatus 59.58 0.00e+00 626.00
IUUC-Laf-054115 Loxodonta africana 85.95 0.00e+00 937.00
IUUC-Mcc-055298 Macaca mulatta 98.47 0.00e+00 1047.00
IUUC-Mor-057263 Magnaporthe oryzae 30.09 2.00e-17 84.00
IUUC-Mpo-057517 Magnaporthe poae 28.51 1.00e-14 74.70
IUUC-Mga-059340 Meleagris gallopavo 72.66 0.00e+00 813.00
IUUC-Mvi-060553 Microbotryum violaceum 27.68 4.00e-15 75.90
IUUC-Mmr-061063 Microcebus murinus 91.93 0.00e+00 962.00
IUUC-Mdo-062075 Monodelphis domestica 80.41 0.00e+00 909.00
IUUC-Mmu-063780 Mus musculus 88.30 0.00e+00 907.00
IUUC-Mac-064529 Musa acuminata 25.00 2.00e-09 56.60
IUUC-Mpu-065748 Mustela putorius furo 89.28 0.00e+00 959.00
IUUC-Mlu-067888 Myotis lucifugus 89.03 0.00e+00 948.00
IUUC-Nle-069234 Nomascus leucogenys 99.62 0.00e+00 1059.00
IUUC-Opr-070393 Ochotona princeps 97.18 9.00e-124 436.00
IUUC-Ont-072459 Oreochromis niloticus 54.06 1.00e-174 605.00
IUUC-Oan-073578 Ornithorhynchus anatinus 81.43 0.00e+00 900.00
IUUC-Ocu-074201 Oryctolagus cuniculus 91.31 0.00e+00 969.00
IUUC-Oba-075457 Oryza barthii 27.59 1.00e-08 53.90
IUUC-Ogl-077406 Oryza glaberrima 27.59 1.00e-08 54.30
IUUC-Ogu-078803 Oryza glumaepatula 27.03 6.00e-09 55.10
IUUC-Oin-079307 Oryza indica 27.59 1.00e-08 54.30
IUUC-Olo-080508 Oryza longistaminata 28.16 4.00e-09 55.50
IUUC-Ome-081315 Oryza meridionalis 26.44 5.00e-08 52.00
IUUC-Oni-082966 Oryza nivara 27.03 6.00e-09 55.10
IUUC-Opu-084160 Oryza punctata 25.86 3.00e-08 52.40
IUUC-Oru-085055 Oryza rufipogon 27.03 6.00e-09 55.10
IUUC-Osa-085780 Oryza sativa 27.59 9.00e-09 54.30
IUUC-Ola-087319 Oryzias latipes 58.94 7.00e-91 327.00
IUUC-Olu-087748 Ostreococcus lucimarinus 23.14 6.00e-11 61.60
IUUC-Oga-087936 Otolemur garnettii 90.28 0.00e+00 960.00
IUUC-Oar-089379 Ovis aries 88.75 0.00e+00 977.00
IUUC-Pan-092590 Papio anubis 98.66 0.00e+00 1048.00
IUUC-Psi-093948 Pelodiscus sinensis 71.48 0.00e+00 805.00
IUUC-Pma-094434 Petromyzon marinus 50.72 3.00e-76 279.00
IUUC-Pfo-096912 Poecilia formosa 52.56 2.00e-168 585.00
IUUC-Pab-097651 Pongo abelii 100.00 0.00e+00 1062.00
IUUC-Pca-100958 Procavia capensis 90.08 0.00e+00 718.00
IUUC-Pva-103247 Pteropus vampyrus 93.25 2.00e-131 462.00
IUUC-Rno-104994 Rattus norvegicus 86.79 0.00e+00 919.00
IUUC-Sha-106494 Sarcophilus harrisii 83.05 0.00e+00 923.00
IUUC-Sar-113375 Sorex araneus 88.43 0.00e+00 935.00
IUUC-Sre-115218 Sporisorium reilianum 27.63 1.00e-15 78.60
IUUC-Ssc-115417 Sus scrofa 89.09 0.00e+00 968.00
IUUC-Tgu-117232 Taeniopygia guttata 72.48 0.00e+00 789.00
IUUC-Tru-118321 Takifugu rubripes 53.42 7.00e-167 580.00
IUUC-Tni-120475 Tetraodon nigroviridis 56.47 7.00e-165 573.00
IUUC-Tbe-127719 Tupaia belangeri 81.25 0.00e+00 829.00
IUUC-Ttr-129264 Tursiops truncatus 89.72 3.00e-126 445.00
IUUC-Uma-129620 Ustilago maydis 27.67 6.00e-17 82.80
IUUC-Vpa-130244 Vicugna pacos 89.33 2.00e-128 452.00
IUUC-Xtr-131948 Xenopus tropicalis 64.87 0.00e+00 748.00
IUUC-Xma-133132 Xiphophorus maculatus 53.09 1.00e-169 589.00
Created Date 25-Jun-2017

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