iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073647

UUCD1 version

UUC-OrA-00411

Ensembl Protein ID

ENSOANP00000004626.2

UniProt Accession

F7B3J5; F7B3J5_ORNAN

Protein Name

Uncharacterized protein

Gene Name

WSB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000002913.2	ENSOANT00000004627.2	ENSOANP00000004626.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.70e-16	60.1	355	402
E3 adaptor/Cullin RING/DCX/DWD	6.40e-31	105.3	149	182
UBD/Beta-Prp	5.90e-44	150.7	128	359

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyed 51
           ++++w++++   SL+hLCR+aIrr+l+++++    +LP+Pk++k++L y++
   Q: 355  HVQFWTAPRALSSLKHLCRRAIRRFLTTYQV---LALPIPKKMKEFLTYRT 402
           689****************************...***************86 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlr 31
           gH+d v++l+f  ++  +lvs+s+D+t+++WDl+
   Q: 149  GHQDVVRDLSFapNGsLILVSASRDKTLRIWDLD 182
           8***********5446778*************96 PP

UBD/Beta-Prp

   S: 29   srdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfspsgdklvsGshd 115
           s+d+ i+vw+v+ g ll+ lsgh++ v++++f p+g+ ilv++s+D+t+++wdl+  gk++++l gh + v+++s+sp+ + l s+   
   Q: 128  SADEHIQVWEVHAGRLLHNLSGHQDVVRDLSFAPNGSlILVSASRDKTLRIWDLDrEGKQIQVLLGHLQWVYCCSVSPDCSMLCSAAGE 216
           6899*********************************9****************999*********************99********* PP
   S: 116  rtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tgghtdsvyslsfdsng 192
           + + +w +++++ ++  l+gh+++v +  ++pd+ llv++s+D+ v +Wd  tg+ lrtl             + h +s +s+ f+++g
   Q: 217  KSALLWSMRSYTLIR-RLEGHRSSVVSCDFSPDSALLVTASYDTDVIMWDPYTGERLRTLshvaarpvadvgGEVHAGSLRSVCFSPEG 304
           ***************.********************************************999999999999555999999999***** PP
   S: 193  kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
            +l+++++d+ +++w l++ +   +  +  +n ++  f+p++ ++++g+ Dg +++W
   Q: 305  LYLATVADDRFLRIWALERRD--PIAFAPMTNGLCCTFFPHGGIVATGTRDGHVQFW 359
           ******************998..7789****************************** PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

LKPGRPHRLD WKSSCETWSV AFSPDAAWFA WSQGHCLVKL IPWPLDEPLL PGRGGGRAFS 60
EVVIVVLGRG LSGGGSAEIG GEGGVIGEEA WRRREPEEVP GGERGVNKRS GRRRGTKSAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGAAGCCGG GCCGACCGCA CCGGCTGGAC TGGAAGTCGA GCTGCGAGAC GTGGAGCGTG 60
GCCTTCTCCC CCGACGCCGC CTGGTTCGCC TGGTCTCAGG GTCACTGCCT CGTCAAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002221	Ailuropoda melanoleuca	84.31	4.00e-136	477.00
IUUC-Apl-004107	Anas platyrhynchos	73.09	8.00e-110	389.00
IUUC-Aca-004354	Anolis carolinensis	60.81	2.00e-136	478.00
IUUC-Bta-012627	Bos taurus	69.15	7.00e-157	546.00
IUUC-Cja-018897	Callithrix jacchus	83.94	3.00e-135	474.00
IUUC-Cfa-020122	Canis familiaris	83.94	4.00e-136	476.00
IUUC-Cpo-022540	Cavia porcellus	83.94	1.00e-136	478.00
IUUC-Csa-023719	Chlorocebus sabaeus	83.58	3.00e-136	477.00
IUUC-Cho-024367	Choloepus hoffmanni	83.94	7.00e-137	479.00
IUUC-Dno-029021	Dasypus novemcinctus	83.58	8.00e-136	476.00
IUUC-Dor-030321	Dipodomys ordii	69.67	6.00e-157	546.00
IUUC-Ete-032955	Echinops telfairi	68.98	1.00e-155	541.00
IUUC-Eca-033485	Equus caballus	83.94	4.00e-136	476.00
IUUC-Fca-035389	Felis catus	84.31	3.00e-136	477.00
IUUC-Fal-037184	Ficedula albicollis	82.12	2.00e-135	474.00
IUUC-Gga-041014	Gallus gallus	81.18	1.00e-123	436.00
IUUC-Ggo-045585	Gorilla gorilla	83.94	8.00e-137	479.00
IUUC-Hsa-046344	Homo sapiens	83.94	7.00e-137	479.00
IUUC-Itr-049085	Ictidomys tridecemlineatus	83.58	2.00e-136	478.00
IUUC-Lch-050131	Latimeria chalumnae	58.27	4.00e-139	486.00
IUUC-Laf-053528	Loxodonta africana	68.91	9.00e-156	542.00
IUUC-Mcc-055665	Macaca mulatta	83.94	7.00e-137	479.00
IUUC-Meu-056054	Macropus eugenii	78.83	5.00e-124	436.00
IUUC-Mga-059326	Meleagris gallopavo	81.62	4.00e-133	467.00
IUUC-Mmr-060815	Microcebus murinus	82.48	6.00e-135	473.00
IUUC-Mdo-062000	Monodelphis domestica	85.04	1.00e-137	482.00
IUUC-Mmu-063927	Mus musculus	83.94	1.00e-136	478.00
IUUC-Mpu-065726	Mustela putorius furo	68.75	6.00e-154	536.00
IUUC-Nle-069680	Nomascus leucogenys	83.94	9.00e-137	479.00
IUUC-Opr-070356	Ochotona princeps	83.94	2.00e-136	478.00
IUUC-Ocu-073973	Oryctolagus cuniculus	83.94	5.00e-136	476.00
IUUC-Oga-088797	Otolemur garnettii	83.64	2.00e-135	474.00
IUUC-Oar-089187	Ovis aries	83.94	1.00e-136	479.00
IUUC-Ptr-091317	Pan troglodytes	83.94	1.00e-136	478.00
IUUC-Pan-092694	Papio anubis	76.87	3.00e-114	404.00
IUUC-Psi-093392	Pelodiscus sinensis	67.90	1.00e-152	532.00
IUUC-Pab-098145	Pongo abelii	83.94	9.00e-137	479.00
IUUC-Pca-100454	Procavia capensis	60.40	2.00e-131	461.00
IUUC-Pva-102986	Pteropus vampyrus	61.79	4.00e-134	470.00
IUUC-Rno-104931	Rattus norvegicus	83.64	2.00e-135	474.00
IUUC-Sha-106476	Sarcophilus harrisii	84.31	4.00e-136	476.00
IUUC-Ssc-115643	Sus scrofa	83.94	2.00e-136	478.00
IUUC-Tru-118082	Takifugu rubripes	42.62	2.00e-85	308.00
IUUC-Tsy-119301	Tarsius syrichta	83.94	1.00e-136	478.00
IUUC-Tni-120198	Tetraodon nigroviridis	43.30	1.00e-86	313.00
IUUC-Ttr-128683	Tursiops truncatus	83.94	2.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence