iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000016293.2	ENSSTOT00000028633.1	ENSSTOP00000017840.1
ENSSTOG00000016293.2	ENSSTOT00000016295.2	ENSSTOP00000014590.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.60e-40	136.6	3	123

Active Site

Position(s)	Description	Evidence
68	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 16   gisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvlls 104
           +++  +vde++l +w+ li+ p++ pY++g+F++ei+fp +YPfkPPk++f tki+hPn++e+G+vCl ++ ++e+W+pa++  +v+ s
   Q: 3    NFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVI-SAENWKPATKTDQVIQS 89
           5667789999**********.**************************************************.5**************** PP
   S: 105  iqsllaepnpesplneeaaellkknreeykkkvr 138
           +++l+++p+pe+pl+++ ae+++k+r+++ k+++
   Q: 90   LIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAE 123
           ******************************9986 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MKNFRNIQVD EANLLTWQGL IVPDNPPYDK GAFRIEINFP AEYPFKPPKI TFKTKIYHPN 60
IDEKGQVCLP VISAENWKPA TKTDQVIQSL IALVNDPQPE HPLRADLAEE YSKDRKKFCK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATTCTGGG AAAGCAGCAG CACCAGATCC AAGATGGCGG CCAGCAGGAG GCTGATGAAG 60
GTAAAAGCCA TTCTCCGGCG CCGGCCGGGC GGGGGGCGGC GTCCCGTGCT CGGGGCTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001446	Ailuropoda melanoleuca	100.00	1.00e-52	197.00
IUUC-Apl-003318	Anas platyrhynchos	100.00	7.00e-67	245.00
IUUC-Aca-005234	Anolis carolinensis	100.00	4.00e-67	246.00
IUUC-Ame-011452	Astyanax mexicanus	96.32	7.00e-64	235.00
IUUC-Bta-012693	Bos taurus	100.00	6.00e-67	245.00
IUUC-Cel-018332	Caenorhabditis elegans	59.70	4.00e-51	192.00
IUUC-Cja-019062	Callithrix jacchus	100.00	3.00e-67	246.00
IUUC-Cfa-020027	Canis familiaris	100.00	3.00e-67	246.00
IUUC-Cpo-022341	Cavia porcellus	100.00	3.00e-67	246.00
IUUC-Cho-024916	Choloepus hoffmanni	94.05	7.00e-33	131.00
IUUC-Cin-025130	Ciona intestinalis	69.92	3.00e-42	163.00
IUUC-Csv-026183	Ciona savignyi	67.67	3.00e-42	163.00
IUUC-Dre-027710	Danio rerio	96.32	1.00e-64	238.00
IUUC-Dno-029371	Dasypus novemcinctus	100.00	1.00e-54	204.00
IUUC-Dor-031017	Dipodomys ordii	94.12	2.00e-60	223.00
IUUC-Dme-031814	Drosophila melanogaster	77.94	9.00e-64	235.00
IUUC-Ete-032754	Echinops telfairi	100.00	3.00e-67	246.00
IUUC-Eca-034188	Equus caballus	100.00	6.00e-67	245.00
IUUC-Eeu-034942	Erinaceus europaeus	98.53	2.00e-66	243.00
IUUC-Fca-036173	Felis catus	100.00	3.00e-67	246.00
IUUC-Fal-036820	Ficedula albicollis	100.00	3.00e-67	246.00
IUUC-Gmo-038480	Gadus morhua	92.65	2.00e-61	227.00
IUUC-Gga-041039	Gallus gallus	100.00	3.00e-67	246.00
IUUC-Gac-041571	Gasterosteus aculeatus	80.00	5.00e-52	196.00
IUUC-Ggo-044482	Gorilla gorilla	100.00	6.00e-67	245.00
IUUC-Hsa-046287	Homo sapiens	100.00	3.00e-67	246.00
IUUC-Lch-049699	Latimeria chalumnae	81.90	1.00e-43	167.00
IUUC-Loc-052000	Lepisosteus oculatus	94.20	1.00e-62	231.00
IUUC-Laf-053833	Loxodonta africana	100.00	1.00e-66	244.00
IUUC-Mcc-054660	Macaca mulatta	100.00	2.00e-67	248.00
IUUC-Meu-056738	Macropus eugenii	100.00	6.00e-37	144.00
IUUC-Mga-060134	Meleagris gallopavo	98.53	1.00e-64	237.00
IUUC-Mmr-061002	Microcebus murinus	100.00	3.00e-66	243.00
IUUC-Mdo-062043	Monodelphis domestica	80.47	2.00e-62	231.00
IUUC-Mmu-063615	Mus musculus	100.00	3.00e-67	246.00
IUUC-Mlu-066971	Myotis lucifugus	100.00	6.00e-67	245.00
IUUC-Nle-070093	Nomascus leucogenys	100.00	6.00e-67	245.00
IUUC-Opr-070315	Ochotona princeps	100.00	3.00e-67	246.00
IUUC-Ont-072036	Oreochromis niloticus	94.12	7.00e-63	232.00
IUUC-Ocu-074565	Oryctolagus cuniculus	100.00	3.00e-67	246.00
IUUC-Ola-086994	Oryzias latipes	86.76	1.00e-67	248.00
IUUC-Oga-088085	Otolemur garnettii	94.12	3.00e-73	266.00
IUUC-Oar-089520	Ovis aries	100.00	6.00e-67	245.00
IUUC-Ptr-090890	Pan troglodytes	99.26	4.00e-77	279.00
IUUC-Pan-092445	Papio anubis	100.00	6.00e-67	245.00
IUUC-Psi-093376	Pelodiscus sinensis	100.00	8.00e-67	245.00
IUUC-Pma-094445	Petromyzon marinus	85.12	8.00e-50	188.00
IUUC-Pfo-096258	Poecilia formosa	94.12	2.00e-62	231.00
IUUC-Pab-097654	Pongo abelii	100.00	3.00e-67	246.00
IUUC-Pca-100712	Procavia capensis	76.47	1.00e-44	171.00
IUUC-Pva-103113	Pteropus vampyrus	100.00	7.00e-67	245.00
IUUC-Sha-106823	Sarcophilus harrisii	100.00	1.00e-66	244.00
IUUC-Sar-113240	Sorex araneus	100.00	7.00e-67	245.00
IUUC-Ssc-115442	Sus scrofa	100.00	3.00e-67	246.00
IUUC-Tgu-117352	Taeniopygia guttata	100.00	6.00e-67	245.00
IUUC-Tru-117653	Takifugu rubripes	94.12	3.00e-63	233.00
IUUC-Tsy-119345	Tarsius syrichta	100.00	9.00e-53	198.00
IUUC-Tni-119709	Tetraodon nigroviridis	94.12	3.00e-63	233.00
IUUC-Tbe-127294	Tupaia belangeri	99.26	7.00e-66	241.00
IUUC-Ttr-128840	Tursiops truncatus	100.00	3.00e-67	246.00
IUUC-Xtr-132650	Xenopus tropicalis	97.79	3.00e-66	243.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence