iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004384

UUCD1 version

UUC-AnC-00545

Ensembl Protein ID

ENSACAP00000004953.3

UniProt Accession

G1KDI9; G1KDI9_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004991.3	ENSACAT00000005066.3	ENSACAP00000004953.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.90e-18	65.2	213	280
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.40e-07	30.8	312	338

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvil+ g+++++ah++vL++ S++F a+f+++  e k ++++++++++p+++ +l++F Ytg l+++e
   Q: 213  CDVILIAGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAK-QEEIKMEGIDPSALWDLVQFAYTGCLELKE 280
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           ++Nclgi++fAd+ +c++L+++a++++
   Q: 312  PSNCLGIRAFADAQGCTELMQVAHNYT 338
           89***********************95 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSNSSRKDFD VKHILRLRWK LFSHPAASAG GCLQPDSSFE HWGPSQSRLL KSQERSGGGA 60
FWKRASSSSS SSSSSSSPRT ASPLNGTLLP ATRLQALAEQ PPRSVFYVES LEEEEAPGEF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGCTGACT GGCTCTCGAA GGCTTTGGAA GGGGCTCTCC CTGGGGGCGC GCGCGGGACT 60
GGGAACTTCA AGGGAGGGAA GGAAGGAAGG AAGGAAGGAA GGAAGGAAGG AAGGAAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0043025--C:neuronal cell body
GO:0007628--P:adult walking behavior
GO:0021680--P:cerebellar Purkinje cell layer development
GO:0016358--P:dendrite development
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001478	Ailuropoda melanoleuca	85.36	0.00e+00	1241.00
IUUC-Apl-003408	Anas platyrhynchos	96.41	0.00e+00	1130.00
IUUC-Bta-012684	Bos taurus	95.38	0.00e+00	1122.00
IUUC-Bci-013875	Botrytis cinerea	27.84	2.00e-17	83.20
IUUC-Cja-019103	Callithrix jacchus	85.75	0.00e+00	1241.00
IUUC-Cfa-020670	Canis familiaris	89.87	0.00e+00	1133.00
IUUC-Cpo-021951	Cavia porcellus	95.04	0.00e+00	1122.00
IUUC-Csa-023607	Chlorocebus sabaeus	94.68	0.00e+00	1115.00
IUUC-Cho-024648	Choloepus hoffmanni	76.78	0.00e+00	1045.00
IUUC-Dno-029854	Dasypus novemcinctus	85.77	0.00e+00	1235.00
IUUC-Dor-030497	Dipodomys ordii	70.44	0.00e+00	898.00
IUUC-Eca-033525	Equus caballus	86.68	0.00e+00	1263.00
IUUC-Fca-035490	Felis catus	95.21	0.00e+00	1117.00
IUUC-Fal-037099	Ficedula albicollis	97.54	0.00e+00	1118.00
IUUC-Gga-041081	Gallus gallus	85.88	0.00e+00	1215.00
IUUC-Gma-043533	Glycine max	33.06	2.00e-39	156.00
IUUC-Ggo-044717	Gorilla gorilla	86.14	0.00e+00	1241.00
IUUC-Hsa-045726	Homo sapiens	86.14	0.00e+00	1241.00
IUUC-Hvu-047224	Hordeum vulgare	32.50	9.00e-39	155.00
IUUC-Itr-048921	Ictidomys tridecemlineatus	86.27	0.00e+00	1246.00
IUUC-Loc-052321	Lepisosteus oculatus	75.23	0.00e+00	1090.00
IUUC-Laf-054378	Loxodonta africana	85.75	0.00e+00	1242.00
IUUC-Mcc-054985	Macaca mulatta	85.75	0.00e+00	1237.00
IUUC-Mmr-061255	Microcebus murinus	76.01	0.00e+00	1041.00
IUUC-Mdo-062369	Monodelphis domestica	86.42	0.00e+00	1253.00
IUUC-Mmu-063334	Mus musculus	84.51	0.00e+00	1231.00
IUUC-Nle-069856	Nomascus leucogenys	86.01	0.00e+00	1239.00
IUUC-Ocu-074469	Oryctolagus cuniculus	85.75	0.00e+00	1238.00
IUUC-Obr-076181	Oryza brachyantha	31.38	4.00e-36	146.00
IUUC-Oin-079973	Oryza indica	31.35	6.00e-35	142.00
IUUC-Opu-083716	Oryza punctata	30.77	1.00e-32	134.00
IUUC-Olu-087696	Ostreococcus lucimarinus	35.95	8.00e-33	133.00
IUUC-Oga-088528	Otolemur garnettii	89.73	0.00e+00	1129.00
IUUC-Oar-089603	Ovis aries	95.21	0.00e+00	1117.00
IUUC-Ptr-090657	Pan troglodytes	85.88	0.00e+00	1238.00
IUUC-Psi-092962	Pelodiscus sinensis	95.55	0.00e+00	1124.00
IUUC-Pab-097812	Pongo abelii	85.62	0.00e+00	1205.00
IUUC-Pva-103042	Pteropus vampyrus	86.68	0.00e+00	1215.00
IUUC-Sbi-114612	Sorghum bicolor	29.24	3.00e-35	143.00
IUUC-Ssc-115880	Sus scrofa	95.37	0.00e+00	1122.00
IUUC-Tgu-116624	Taeniopygia guttata	95.18	0.00e+00	984.00
IUUC-Tsy-119339	Tarsius syrichta	78.95	0.00e+00	1102.00
IUUC-Tbe-127398	Tupaia belangeri	97.51	0.00e+00	669.00
IUUC-Ttr-129024	Tursiops truncatus	85.66	0.00e+00	1264.00
IUUC-Vpa-130515	Vicugna pacos	95.37	0.00e+00	1123.00
IUUC-Vvi-131673	Vitis vinifera	34.16	5.00e-43	169.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence