iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065806

Ensembl Protein ID

ENSMPUP00000018013.1

UniProt Accession

M3Z351; M3Z351_MUSPF

Genbank Protein ID

ENSMPUP00000018013

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01102344

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000018125.1	ENSMPUT00000018276.1	ENSMPUP00000018013.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-48	159.2	2115	2146
UBD/Beta-Prp	2.10e-81	273.4	1991	2198

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrt 32
           H d+vt++a+  d+llvs+s Dg++ +WD+ +
   Q: 2115 HRDWVTGCAWtRDNLLVSCSSDGSVGLWDPGQ 2146
           9*********988****************765 PP

UBD/Beta-Prp

   S: 24   llatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvw.........dlstgkcvhtlkghedsvls 99
           +l++g +dg+++ w ++ g+l  l+ ls  +++v  +  s++  +l+++seD t+++w           ++++    l++he  v +
   Q: 1991 VLVSGAEDGSLQGWTLKGGSLqsLWLLSRYQKPVLGLATSKE--LLASASEDFTVRLWprqlltlaqTAEDFPRDTELRKHEGPVSC 2075
           799******************999999**************9..9*************665555544444888889999******** PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           +sfs +g +l++G++dr + +wd++          + + h+++v++ ++   +nllvs+s D+ v lWd  +++ l ++ g h+++v
   Q: 2076 CSFSTDGGRLATGGRDRNLFCWDVRMPRAPVLicsFSACHRDWVTGCAWTR-DNLLVSCSSDGSVGLWDPGQQQQLGHFLG-HQSAV 2160
           ************************98665444477999***********99.99**************************9.***** PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdn 224
             +   +  +++vs+++dgt+k+wd q  e + +  +h+ +
   Q: 2161 SAVVAAE--EHVVSVGRDGTLKVWDHQGVE-LTSIPAHSGP 2198
           9999999..79**************98544.5566666555 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MEKLHRHASA HLDILSLENR SLATLPNLQP MEKPHGHVSA HADIFSLENR CLATLPDLKI 60
MEKPRGHVSA HPDILSLENQ CLATLPDLKT MEKLHGHVSV HPDILSLENR CLATLPVLKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATAGGAG GAGAACATGC CAAAATCCCT CCCCAGAAGC CGAGTTTGAG GACACAACAG 60
GAGAAAGGAG GAGGCGGGAG GGGGAGTGCG AGGGACGCGA GTGGGGCGGG GACTAAAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005697--C:telomerase holoenzyme complex
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	88.86	0.00e+00	4419.00
IUUC-Aca-005102	Anolis carolinensis	41.99	0.00e+00	1673.00
IUUC-Ame-011822	Astyanax mexicanus	35.21	0.00e+00	657.00
IUUC-Bta-012323	Bos taurus	78.60	0.00e+00	3888.00
IUUC-Cja-019005	Callithrix jacchus	78.06	0.00e+00	3982.00
IUUC-Cfa-020803	Canis familiaris	79.18	0.00e+00	3773.00
IUUC-Cpo-022312	Cavia porcellus	72.06	0.00e+00	3380.00
IUUC-Csa-023287	Chlorocebus sabaeus	78.69	0.00e+00	3942.00
IUUC-Dre-028825	Danio rerio	35.05	0.00e+00	1169.00
IUUC-Dno-029455	Dasypus novemcinctus	75.85	0.00e+00	3624.00
IUUC-Dor-030328	Dipodomys ordii	70.96	0.00e+00	2468.00
IUUC-Ete-032385	Echinops telfairi	71.81	0.00e+00	1880.00
IUUC-Eca-033726	Equus caballus	82.09	0.00e+00	4083.00
IUUC-Eeu-034665	Erinaceus europaeus	61.74	0.00e+00	930.00
IUUC-Fca-035365	Felis catus	84.88	0.00e+00	4239.00
IUUC-Gmo-039584	Gadus morhua	31.90	4.00e-121	430.00
IUUC-Gac-042307	Gasterosteus aculeatus	36.54	0.00e+00	1024.00
IUUC-Ggo-045432	Gorilla gorilla	75.93	0.00e+00	3694.00
IUUC-Hsa-046182	Homo sapiens	78.02	0.00e+00	3932.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	76.27	0.00e+00	3770.00
IUUC-Lch-050186	Latimeria chalumnae	39.30	3.00e-82	298.00
IUUC-Laf-054524	Loxodonta africana	76.44	0.00e+00	3846.00
IUUC-Mcc-055628	Macaca mulatta	79.09	0.00e+00	3957.00
IUUC-Meu-056338	Macropus eugenii	62.04	0.00e+00	1243.00
IUUC-Mmr-060854	Microcebus murinus	78.10	0.00e+00	3848.00
IUUC-Mdo-062247	Monodelphis domestica	59.24	0.00e+00	2724.00
IUUC-Mmu-064406	Mus musculus	71.16	0.00e+00	3455.00
IUUC-Mlu-068116	Myotis lucifugus	80.51	0.00e+00	3848.00
IUUC-Nle-069628	Nomascus leucogenys	79.18	0.00e+00	3517.00
IUUC-Opr-070242	Ochotona princeps	75.96	0.00e+00	2735.00
IUUC-Oan-073598	Ornithorhynchus anatinus	52.27	0.00e+00	1928.00
IUUC-Ocu-073933	Oryctolagus cuniculus	77.09	0.00e+00	3739.00
IUUC-Ola-086886	Oryzias latipes	35.18	0.00e+00	1036.00
IUUC-Oga-088609	Otolemur garnettii	75.58	0.00e+00	3749.00
IUUC-Oar-089957	Ovis aries	78.39	0.00e+00	3801.00
IUUC-Ptr-090577	Pan troglodytes	76.70	0.00e+00	3872.00
IUUC-Pan-092397	Papio anubis	78.64	0.00e+00	3938.00
IUUC-Pma-094373	Petromyzon marinus	35.27	3.00e-73	269.00
IUUC-Pfo-096497	Poecilia formosa	36.27	0.00e+00	1061.00
IUUC-Pab-098028	Pongo abelii	78.18	0.00e+00	3922.00
IUUC-Pca-101002	Procavia capensis	81.04	0.00e+00	1859.00
IUUC-Pva-102144	Pteropus vampyrus	72.25	0.00e+00	1668.00
IUUC-Rno-105828	Rattus norvegicus	70.39	0.00e+00	3494.00
IUUC-Sha-106469	Sarcophilus harrisii	59.02	0.00e+00	2806.00
IUUC-Sar-113035	Sorex araneus	75.51	0.00e+00	1450.00
IUUC-Ssc-116122	Sus scrofa	81.05	0.00e+00	2944.00
IUUC-Tru-118412	Takifugu rubripes	33.26	0.00e+00	1160.00
IUUC-Tsy-119257	Tarsius syrichta	72.04	0.00e+00	1514.00
IUUC-Tni-120032	Tetraodon nigroviridis	36.63	3.00e-44	172.00
IUUC-Tbe-127312	Tupaia belangeri	64.69	0.00e+00	938.00
IUUC-Ttr-128335	Tursiops truncatus	76.46	0.00e+00	3831.00
IUUC-Xtr-132524	Xenopus tropicalis	39.43	0.00e+00	1362.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence