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Tag Content
UUCD2 ID IUUC-Ocu-074273
UUCD1 version UUC-OrC-00253
Ensembl Protein ID ENSOCUP00000005856.3
UniProt Accession G1SRN9; G1SRN9_RABIT
Genbank Protein ID ENSOCUP00000005856
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAGW02050270
Gene Name HERC2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOCUG00000006754.3 ENSOCUT00000006773.3 ENSOCUP00000005856.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 4.70e-84 282.7 4476 4806
Active Site
Position(s) Description Evidence
4775 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFefl.Grllgkalqdgrl 87
           ++++v+fvgE++ d+gG  +e +a++++elqn  ++l+  ++n++ +   n+d +l np      h ++F+fl G+llg+a+++g +
   Q: 4476 RVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLFNPaarapVHSSMFRFLaGVLLGIAIRTGSP 4562
           4566***********************************************************9*******966************* PP
   S: 88   ldlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYv 174
           l l+l+++++k+l g +l++ dl+evd++++  l++i++n+ ++ e +++ l f+     +++++ +++  +++ +++t +N+ eYv
   Q: 4563 LSLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFT-----VPSASGQDIQLSSKYTHITLDNRAEYV 4644
           ****************************************9999999999***99.....788999999****************** PP
   S: 175  klvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseer 261
           +l ++yrl+e ++eqv+a+reG+ +v+p  llslFt  ele+++cG+++i ++ lk+ ++ykg ++++ + iqwFwev+e+fs++er
   Q: 4645 RLAINYRLHE-FDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKG-IEPSASLIQWFWEVMESFSNTER 4729
           **********.**************************************************77.*********************** PP
   S: 262  kafLqFvTgssrlPlgGfaelkprlfvirk....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           + fL+Fv+g+ rlP + +a+++ r fvi+     +  d+ lP+s TCf++LkLP+Ys k++l+ekL yAi+ +k++++
   Q: 4730 SLFLRFVWGRTRLP-RTIADFRGRDFVIQVldkyNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDT 4806
           **************.8*************999988888***********************************99875 PP
   
Organism Oryctolagus cuniculus
Protein Sequence
(Fasta)
MPSESFCLAA QARLDSKWLK TDIQLAFTRD GLCGLWNEMV KDGEIVYTGT ELTQNGELPP 60
RKDDGVDTSS GTKKEDLNDK EKKDEEEIPA PAYRAKSILE SWVWGKQPDV NELKECLSVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ocu-074273|E3,HECT|Oryctolagus cuniculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGAGATCCA AAGAGGAAGA TATGAGAGAT CGAAGAAAGC AGGGGAGTAG GGAGGAGCGG 60
CGAAGGGGTT CCTCTTCCCC ATTGGCTGTG CCCGCGCAGT AGCCTCTCTG CGATTGGCTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ocu-074273|E3,HECT|Oryctolagus cuniculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR004939--APC_su10/DOC_dom
IPR006624--Beta-propeller_rpt_TECPR
IPR016186--C-type_lectin-like/link
IPR021097--CPH_domain
IPR001199--Cyt_B5-like_heme/steroid-bd
IPR008979--Galactose-bd-like
IPR000569--HECT_dom
IPR010606--Mib_Herc2
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
IPR014722--Rib_L2_dom2
IPR000433--Znf_ZZ
PROSITE

PS50255--CYTOCHROME_B5_2
PS51284--DOC
PS50237--HECT
PS51416--MIB_HERC2
PS00626--RCC1_2
PS50012--RCC1_3
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2
Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00173--Cyt-b5
PF00632--HECT
PF06701--MIB_HERC2
PF00415--RCC1
PF00569--ZZ
PRINTS

PR00633--RCCNDNSATION
SMART

SM01337--APC10
SM01117--Cyt-b5
SM00119--HECTc
SM00706--TECPR
SM00291--ZnF_ZZ
Gene Ontology

GO:0005743--C:mitochondrial inner membrane
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0007283--P:spermatogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002112 Ailuropoda melanoleuca 96.97 0.00e+00 7206.00
IUUC-Atr-003065 Amborella trichopoda 35.59 4.00e-51 196.00
IUUC-Apl-003983 Anas platyrhynchos 90.53 0.00e+00 8322.00
IUUC-Aca-004300 Anolis carolinensis 89.78 0.00e+00 8199.00
IUUC-Aly-006441 Arabidopsis lyrata 34.15 9.00e-45 175.00
IUUC-Ame-010621 Astyanax mexicanus 84.01 0.00e+00 6874.00
IUUC-Bta-013067 Bos taurus 95.31 0.00e+00 8601.00
IUUC-Bdi-014093 Brachypodium distachyon 33.25 2.00e-49 191.00
IUUC-Bol-015203 Brassica oleracea 34.55 1.00e-52 201.00
IUUC-Bra-016737 Brassica rapa 34.55 4.00e-48 186.00
IUUC-Cja-019687 Callithrix jacchus 94.75 0.00e+00 8491.00
IUUC-Cfa-020672 Canis familiaris 96.14 0.00e+00 8706.00
IUUC-Cpo-021819 Cavia porcellus 93.94 0.00e+00 8496.00
IUUC-Csa-023817 Chlorocebus sabaeus 96.25 0.00e+00 8675.00
IUUC-Cho-024387 Choloepus hoffmanni 95.57 0.00e+00 1900.00
IUUC-Cin-025709 Ciona intestinalis 54.86 0.00e+00 2224.00
IUUC-Csv-026336 Ciona savignyi 41.74 0.00e+00 2961.00
IUUC-Dre-027717 Danio rerio 81.42 0.00e+00 7212.00
IUUC-Dno-029296 Dasypus novemcinctus 95.09 0.00e+00 8602.00
IUUC-Dor-030979 Dipodomys ordii 91.94 0.00e+00 2947.00
IUUC-Dme-032171 Drosophila melanogaster 60.37 0.00e+00 1527.00
IUUC-Ete-032687 Echinops telfairi 83.65 0.00e+00 2806.00
IUUC-Eca-034046 Equus caballus 95.38 0.00e+00 8634.00
IUUC-Eeu-034859 Erinaceus europaeus 94.29 0.00e+00 1942.00
IUUC-Fca-036262 Felis catus 96.12 0.00e+00 8734.00
IUUC-Fal-037562 Ficedula albicollis 90.35 0.00e+00 8253.00
IUUC-Gmo-039054 Gadus morhua 86.48 0.00e+00 1085.00
IUUC-Gga-040359 Gallus gallus 90.62 0.00e+00 8284.00
IUUC-Gac-041879 Gasterosteus aculeatus 90.93 0.00e+00 1048.00
IUUC-Ggo-044692 Gorilla gorilla 97.58 0.00e+00 4336.00
IUUC-Hsa-045995 Homo sapiens 96.45 0.00e+00 8727.00
IUUC-Hvu-047529 Hordeum vulgare 35.65 2.00e-49 191.00
IUUC-Itr-048553 Ictidomys tridecemlineatus 96.24 0.00e+00 2463.00
IUUC-Lch-049808 Latimeria chalumnae 87.32 0.00e+00 3367.00
IUUC-Lpe-051482 Leersia perrieri 33.94 4.00e-46 180.00
IUUC-Loc-052685 Lepisosteus oculatus 84.10 0.00e+00 7500.00
IUUC-Laf-053372 Loxodonta africana 94.37 0.00e+00 8545.00
IUUC-Mcc-054693 Macaca mulatta 96.35 0.00e+00 8722.00
IUUC-Meu-056660 Macropus eugenii 96.11 0.00e+00 1925.00
IUUC-Mga-059371 Meleagris gallopavo 91.33 0.00e+00 7215.00
IUUC-Mmr-060787 Microcebus murinus 96.84 0.00e+00 8826.00
IUUC-Mdo-062518 Monodelphis domestica 88.87 0.00e+00 8002.00
IUUC-Mmu-063690 Mus musculus 95.28 0.00e+00 8615.00
IUUC-Mpu-066478 Mustela putorius furo 96.00 0.00e+00 8671.00
IUUC-Mlu-067596 Myotis lucifugus 89.95 0.00e+00 4354.00
IUUC-Nle-069445 Nomascus leucogenys 96.11 0.00e+00 2204.00
IUUC-Opr-070990 Ochotona princeps 88.99 0.00e+00 3032.00
IUUC-Ont-072285 Oreochromis niloticus 82.55 0.00e+00 7302.00
IUUC-Oan-072721 Ornithorhynchus anatinus 86.66 0.00e+00 3458.00
IUUC-Oba-075573 Oryza barthii 33.68 1.00e-45 178.00
IUUC-Obr-076107 Oryza brachyantha 33.77 4.00e-50 193.00
IUUC-Ogl-077193 Oryza glaberrima 33.68 1.00e-45 178.00
IUUC-Ogu-078817 Oryza glumaepatula 33.68 1.00e-45 178.00
IUUC-Oin-079609 Oryza indica 32.75 2.00e-49 190.00
IUUC-Olo-080629 Oryza longistaminata 33.68 1.00e-45 178.00
IUUC-Ome-081686 Oryza meridionalis 33.68 4.00e-46 180.00
IUUC-Opu-084137 Oryza punctata 33.94 2.00e-46 181.00
IUUC-Oru-085013 Oryza rufipogon 33.68 1.00e-45 178.00
IUUC-Osa-085597 Oryza sativa 33.68 1.00e-45 178.00
IUUC-Ola-087346 Oryzias latipes 92.56 0.00e+00 1194.00
IUUC-Oga-088742 Otolemur garnettii 95.88 0.00e+00 8610.00
IUUC-Oar-090093 Ovis aries 95.55 0.00e+00 8645.00
IUUC-Ptr-091034 Pan troglodytes 91.38 0.00e+00 5736.00
IUUC-Pan-092783 Papio anubis 93.94 0.00e+00 8463.00
IUUC-Psi-094027 Pelodiscus sinensis 90.51 0.00e+00 7932.00
IUUC-Pfo-096208 Poecilia formosa 79.95 0.00e+00 5956.00
IUUC-Pab-097681 Pongo abelii 94.11 0.00e+00 2613.00
IUUC-Pca-100705 Procavia capensis 95.51 0.00e+00 1171.00
IUUC-Pva-103147 Pteropus vampyrus 87.27 0.00e+00 2531.00
IUUC-Rno-105458 Rattus norvegicus 95.30 0.00e+00 8603.00
IUUC-Sha-106959 Sarcophilus harrisii 81.92 0.00e+00 7000.00
IUUC-Sit-109917 Setaria italica 36.47 5.00e-48 186.00
IUUC-Sly-110961 Solanum lycopersicum 35.33 4.00e-53 203.00
IUUC-Sar-113532 Sorex araneus 85.65 0.00e+00 1831.00
IUUC-Sbi-114352 Sorghum bicolor 32.39 9.00e-50 192.00
IUUC-Ssc-115337 Sus scrofa 93.09 0.00e+00 3043.00
IUUC-Tgu-116789 Taeniopygia guttata 90.30 0.00e+00 8270.00
IUUC-Tru-118129 Takifugu rubripes 81.87 0.00e+00 7331.00
IUUC-Tsy-119302 Tarsius syrichta 85.08 0.00e+00 1281.00
IUUC-Tni-120374 Tetraodon nigroviridis 80.46 0.00e+00 7185.00
IUUC-Tca-121094 Theobroma cacao 35.31 7.00e-54 206.00
IUUC-Tae-124157 Triticum aestivum 33.51 9.00e-50 192.00
IUUC-Tur-126300 Triticum urartu 35.29 1.00e-49 192.00
IUUC-Tbe-128137 Tupaia belangeri 86.14 0.00e+00 2258.00
IUUC-Ttr-128273 Tursiops truncatus 91.02 0.00e+00 6387.00
IUUC-Vpa-130471 Vicugna pacos 83.37 0.00e+00 1485.00
IUUC-Xtr-132185 Xenopus tropicalis 85.17 0.00e+00 7706.00
IUUC-Xma-133233 Xiphophorus maculatus 82.27 0.00e+00 7295.00
Created Date 25-Jun-2017

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