iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048167

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01002637

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000000278.2	ENSSTOT00000000278.2	ENSSTOP00000000248.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-89	300.2	47	363

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtCYmN++LQcL +i++l e++l+ k+  +l+     ++  e++++++ l++ +w +++  vsp+ + +al+++ + f +  
   Q: 47   TGLRNLGNTCYMNAILQCLCSISPLVEYFLSgKYMTALQ-----KDCSEVATAFAYLMTDMWLGDSDCVSPEVFRSALGNLYPAFMKKT 130
           7******************************44444444.....5678***************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           qqDaqEfl ++l++l+e+lkk     +++ ++ +++ +s+   +k    ++s+i++lF+gql   i+cl+c+n + ++e f+ lslp+p
   Q: 131  QQDAQEFLIYVLNELHEALKK-----YHRRRS-HEKGSSQRCCRKVIANETSIITRLFEGQLNYGIICLKCENCTYKNEVFTVLSLPIP 213
           *******************44.....444433.3345566778999999**************************************** PP
   S: 178  gkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfc 265
           ++ e+   slqdcL+ f+++++l+ +n+++c+ c+ kqe+  + +++k P+++i+hLkRf  + ++  ++k+ + +++pl+ Ldl+p+ 
   Q: 214  SEYEC---SLQDCLQCFFQQDTLTWNNQIHCSFCETKQETAVRASISKAPKIIIFHLKRF--DIQGTLKRKLRTDIHYPLTnLDLTPYI 297
           *****...****************************************************..6677899******************** PP
   S: 266  tspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           +   +k   + kY+L+avv+H G l++GHY+a++kn+  + W+ fdD++V+e++e++v++   +taY+lfY 
   Q: 298  CPVFRK---HPKYNLCAVVNHFGDLDGGHYTAFCKNSVTQaWYSFDDTRVSEIPETSVQT---ATAYLLFYS 363
           *95544...89*************************98888*******************...********6 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

SIKMTSHQSF PADDFGIYYV LAECTDYYDS LPVNEADENQ PHSQGVTGLR NLGNTCYMNA 60
ILQCLCSISP LVEYFLSGKY MTALQKDCSE VATAFAYLMT DMWLGDSDCV SPEVFRSALG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTATTAAAA TGACTTCTCA TCAGTCATTC CCTGCAGACG ACTTCGGTAT CTACTATGTC 60
CTGTGAGCCT CTATTTATTA CAGCTTTCTA GATAAGCTCA GGTAGAGAGA AGAGCTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	90.37	0.00e+00	713.00
IUUC-Aca-005256	Anolis carolinensis	51.94	8.00e-106	376.00
IUUC-Bta-012753	Bos taurus	84.22	0.00e+00	666.00
IUUC-Cfa-020054	Canis familiaris	88.32	2.00e-179	620.00
IUUC-Cpo-021375	Cavia porcellus	80.68	1.00e-173	601.00
IUUC-Csa-023902	Chlorocebus sabaeus	88.64	6.00e-115	405.00
IUUC-Cho-024755	Choloepus hoffmanni	77.81	2.00e-153	534.00
IUUC-Dor-030311	Dipodomys ordii	90.81	6.00e-99	353.00
IUUC-Ete-032570	Echinops telfairi	67.12	9.00e-112	395.00
IUUC-Eca-034343	Equus caballus	90.37	0.00e+00	712.00
IUUC-Eeu-034510	Erinaceus europaeus	87.77	2.00e-172	597.00
IUUC-Fca-035920	Felis catus	89.01	0.00e+00	704.00
IUUC-Fal-036903	Ficedula albicollis	59.13	9.00e-110	389.00
IUUC-Gac-042261	Gasterosteus aculeatus	42.90	4.00e-74	271.00
IUUC-Ggo-045650	Gorilla gorilla	57.36	1.00e-94	338.00
IUUC-Hsa-046665	Homo sapiens	84.84	2.00e-172	597.00
IUUC-Lch-049925	Latimeria chalumnae	53.41	9.00e-107	379.00
IUUC-Loc-051880	Lepisosteus oculatus	48.60	1.00e-82	300.00
IUUC-Laf-054494	Loxodonta africana	91.08	0.00e+00	716.00
IUUC-Mcc-055507	Macaca mulatta	91.43	0.00e+00	676.00
IUUC-Meu-055906	Macropus eugenii	78.08	1.00e-158	551.00
IUUC-Mmr-061564	Microcebus murinus	66.86	4.00e-118	416.00
IUUC-Mdo-061800	Monodelphis domestica	80.82	0.00e+00	630.00
IUUC-Mmu-063618	Mus musculus	84.53	0.00e+00	662.00
IUUC-Mpu-066699	Mustela putorius furo	90.35	0.00e+00	715.00
IUUC-Mlu-067672	Myotis lucifugus	87.33	0.00e+00	686.00
IUUC-Opr-070949	Ochotona princeps	90.16	1.00e-168	585.00
IUUC-Oan-073725	Ornithorhynchus anatinus	66.85	8.00e-145	506.00
IUUC-Ocu-074021	Oryctolagus cuniculus	94.10	0.00e+00	744.00
IUUC-Oga-088258	Otolemur garnettii	92.41	1.00e-177	615.00
IUUC-Oar-089881	Ovis aries	87.17	0.00e+00	696.00
IUUC-Ptr-090988	Pan troglodytes	85.37	1.00e-168	584.00
IUUC-Pan-091773	Papio anubis	90.59	0.00e+00	708.00
IUUC-Psi-093243	Pelodiscus sinensis	74.21	3.00e-142	497.00
IUUC-Pab-097713	Pongo abelii	86.40	0.00e+00	637.00
IUUC-Pca-100226	Procavia capensis	71.30	3.00e-141	493.00
IUUC-Pva-103172	Pteropus vampyrus	89.35	0.00e+00	639.00
IUUC-Rno-105950	Rattus norvegicus	86.60	0.00e+00	676.00
IUUC-Sha-107026	Sarcophilus harrisii	80.91	4.00e-176	610.00
IUUC-Ssc-116383	Sus scrofa	91.44	0.00e+00	727.00
IUUC-Tgu-116511	Taeniopygia guttata	57.27	3.00e-103	367.00
IUUC-Tbe-127808	Tupaia belangeri	86.13	7.00e-66	243.00
IUUC-Ttr-129046	Tursiops truncatus	86.69	1.00e-176	612.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence