iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072200

Ensembl Protein ID

ENSONIP00000000237.1

UniProt Accession

I3IUE7; I3IUE7_ORENI

Genbank Protein ID

ENSONIP00000000237

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01049880

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000000183.1	ENSONIT00000000236.1	ENSONIP00000000237.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-80	271.5	137	457

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N gN+CY+N+vLQcL ++ +l e ll+   +++++e  +++k ++++ + +l+ee+w +++++ +p e  ++l+++ ++f++y+q
   Q: 137  CGLDNSGNSCYLNAVLQCLCSTVPLVEHLLD---QETRRE-LEKSKCRVAEVFVRLLEEMWLGTNSSCAPVEARSVLCSILPQFNNYSQ 221
           7******************************...555544.36899******************************************* PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           qDaqE+l fll++l+++lkk     + + +   ++++++++ +++   +++++s+lF+gql+  + c +cd++  +++ f+ lslp+p 
   Q: 222  QDAQELLLFLLNALHDDLKK-----VAKDQMRCSIRQPRQEHNRNCATESTIVSQLFEGQLSYITLCMHCDQQAYSTQAFTVLSLPIPA 305
           ******************44.....3333334456677777889999999**************************************8 PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
                k s+qdcL+ f+++  l+g +++ c+ c+ ++e+   ++l+k Pe+L+lhLkRf   +++k++ k+ ++v fp +Ldl+pf++s
   Q: 306  GI--LKCSIQDCLSLFFEQTVLTGGEQLLCSVCRMRRETAVITSLDKPPEILMLHLKRF--GCKGKKQVKLRTNVAFPMKLDLTPFLSS 390
           87..456****************************************************..889999********************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           +  +++ + +Y L+avv+H+G l+ GHY+a++ n + + W lfdDs V+ev+ + v++    +aY+l+Y r
   Q: 391  SVHNVS-DSSYHLYAVVNHTGHLNMGHYTALCHNASAQtWHLFDDSLVREVQDTLVQS---PNAYMLLYSR 457
           888885.***************************99989*******************...********98 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MSELIAHLQG WTGPALVPLS DPKGTATDVF LPGLWVTLHV ICINTFVLHT LQSQSSGKKV 60
NLTQFTRTLA SQLAVNSSTA VPVLPRLNSS SYQEKNVSNI CKQRTNTNIC GQVTVKGKHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGTTTACG TTGCCAGGAC ACATTTGTCT GGCTACTGCG GATCCCAGGT GAATTACCTA 60
AAAGCGGATT CTCCTGAGCG CTGGTTTCAC CTGAGGATCA GATGAACATG AACAGCACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	45.65	2.00e-75	275.00
IUUC-Dor-030311	Dipodomys ordii	44.57	5.00e-39	154.00
IUUC-Ete-032570	Echinops telfairi	35.04	1.00e-31	130.00
IUUC-Gac-042261	Gasterosteus aculeatus	72.02	5.00e-130	457.00
IUUC-Hsa-046665	Homo sapiens	42.58	5.00e-59	221.00
IUUC-Loc-051880	Lepisosteus oculatus	46.61	1.00e-98	354.00
IUUC-Laf-054494	Loxodonta africana	45.78	2.00e-76	279.00
IUUC-Mcc-055507	Macaca mulatta	44.69	2.00e-70	259.00
IUUC-Mlu-067672	Myotis lucifugus	45.26	1.00e-74	273.00
IUUC-Ola-086857	Oryzias latipes	65.22	2.00e-125	441.00
IUUC-Ptr-090988	Pan troglodytes	41.58	3.00e-56	212.00
IUUC-Pan-091773	Papio anubis	45.12	5.00e-76	278.00
IUUC-Pfo-096718	Poecilia formosa	62.45	6.00e-150	524.00
IUUC-Rno-105950	Rattus norvegicus	45.48	4.00e-76	278.00
IUUC-Tru-118574	Takifugu rubripes	71.65	3.00e-128	451.00
IUUC-Tni-120385	Tetraodon nigroviridis	71.87	1.00e-114	405.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence