iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035693

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02156571

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000012572.3	ENSFCAT00000012575.3	ENSFCAP00000011665.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-42	141.5	237	277
UBD/Beta-Prp	1.70e-54	185.0	191	396

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++
   Q: 237  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCVQ 277
           8***********9644499********************98 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 191  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ-A 278
           567889999*********99***************************************9778************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 279  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 367
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++r+W
   Q: 368  HENRVSTLRVSPDGTAFCSGSWDHTLRVW 396
           ***************************** PP

Organism

Felis catus

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCFKQ RALRPVFKKS QQLSYCSMCA EIKCTHGLSD NSKISSTSEE 60
MHSLQPQAQW HCTRGRSHGI PLHQVAERVE ALGQFVMKTR RTLKGHGNKV LCMDWCKDKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGATC AGACCTTTCT AGTTAACGTA TTTGGCTCCT GTGACAAATG TTTCAAACAA 60
CGAGCTCTGA GACCAGTTTT CAAGAAATCT CAACAGCTCA GCTACTGTTC AATGTGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	90.68	0.00e+00	743.00
IUUC-Apl-003399	Anas platyrhynchos	98.72	0.00e+00	647.00
IUUC-Aca-004861	Anolis carolinensis	86.65	0.00e+00	728.00
IUUC-Ame-011851	Astyanax mexicanus	88.66	0.00e+00	643.00
IUUC-Bta-012438	Bos taurus	92.31	0.00e+00	674.00
IUUC-Cel-018408	Caenorhabditis elegans	59.89	2.00e-132	465.00
IUUC-Cja-019086	Callithrix jacchus	92.41	0.00e+00	758.00
IUUC-Cfa-021255	Canis familiaris	90.89	0.00e+00	737.00
IUUC-Cpo-021398	Cavia porcellus	90.20	0.00e+00	743.00
IUUC-Csa-023776	Chlorocebus sabaeus	92.07	0.00e+00	675.00
IUUC-Cin-025305	Ciona intestinalis	61.30	5.00e-123	434.00
IUUC-Csv-026058	Ciona savignyi	61.37	8.00e-123	433.00
IUUC-Dre-028432	Danio rerio	79.60	0.00e+00	658.00
IUUC-Dno-029958	Dasypus novemcinctus	81.63	5.00e-137	479.00
IUUC-Dor-031013	Dipodomys ordii	99.22	3.00e-152	531.00
IUUC-Dme-031889	Drosophila melanogaster	64.35	4.00e-139	487.00
IUUC-Ete-033033	Echinops telfairi	69.29	3.00e-150	524.00
IUUC-Eca-033977	Equus caballus	91.44	0.00e+00	741.00
IUUC-Eeu-035079	Erinaceus europaeus	91.37	0.00e+00	742.00
IUUC-Fal-037345	Ficedula albicollis	90.93	0.00e+00	671.00
IUUC-Gmo-039222	Gadus morhua	92.28	0.00e+00	640.00
IUUC-Gga-040320	Gallus gallus	91.22	0.00e+00	673.00
IUUC-Gac-042644	Gasterosteus aculeatus	86.12	0.00e+00	644.00
IUUC-Ggo-044489	Gorilla gorilla	91.41	0.00e+00	749.00
IUUC-Hsa-046434	Homo sapiens	92.44	0.00e+00	762.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	94.30	5.00e-177	613.00
IUUC-Loc-052790	Lepisosteus oculatus	84.26	0.00e+00	692.00
IUUC-Laf-054255	Loxodonta africana	90.89	0.00e+00	746.00
IUUC-Mcc-055610	Macaca mulatta	91.90	0.00e+00	754.00
IUUC-Meu-056819	Macropus eugenii	86.04	0.00e+00	684.00
IUUC-Mga-059740	Meleagris gallopavo	84.52	0.00e+00	703.00
IUUC-Mmr-061221	Microcebus murinus	92.19	0.00e+00	759.00
IUUC-Mdo-062619	Monodelphis domestica	91.48	0.00e+00	672.00
IUUC-Mmu-064266	Mus musculus	91.94	0.00e+00	760.00
IUUC-Mpu-065766	Mustela putorius furo	99.34	0.00e+00	625.00
IUUC-Mlu-067221	Myotis lucifugus	89.72	0.00e+00	729.00
IUUC-Nle-069515	Nomascus leucogenys	95.83	0.00e+00	665.00
IUUC-Opr-070195	Ochotona princeps	83.80	0.00e+00	670.00
IUUC-Ont-071535	Oreochromis niloticus	73.55	1.00e-166	578.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	5.00e-107	379.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.67	0.00e+00	625.00
IUUC-Ola-086578	Oryzias latipes	94.04	0.00e+00	639.00
IUUC-Oga-089090	Otolemur garnettii	91.73	0.00e+00	755.00
IUUC-Oar-090017	Ovis aries	89.90	0.00e+00	725.00
IUUC-Ptr-091280	Pan troglodytes	89.67	0.00e+00	723.00
IUUC-Pan-092198	Papio anubis	95.83	0.00e+00	664.00
IUUC-Psi-093030	Pelodiscus sinensis	84.37	0.00e+00	707.00
IUUC-Pma-094140	Petromyzon marinus	73.02	3.00e-91	327.00
IUUC-Pfo-097182	Poecilia formosa	92.90	0.00e+00	643.00
IUUC-Pab-098157	Pongo abelii	92.35	0.00e+00	677.00
IUUC-Pca-100988	Procavia capensis	70.78	6.00e-155	540.00
IUUC-Pva-102232	Pteropus vampyrus	100.00	5.00e-161	560.00
IUUC-Rno-105526	Rattus norvegicus	88.45	0.00e+00	638.00
IUUC-Sha-106754	Sarcophilus harrisii	90.18	0.00e+00	731.00
IUUC-Ssc-115390	Sus scrofa	91.96	0.00e+00	757.00
IUUC-Tgu-117377	Taeniopygia guttata	86.15	0.00e+00	690.00
IUUC-Tru-117938	Takifugu rubripes	93.75	0.00e+00	640.00
IUUC-Tsy-119392	Tarsius syrichta	80.60	0.00e+00	629.00
IUUC-Tni-119834	Tetraodon nigroviridis	67.76	2.00e-157	548.00
IUUC-Tbe-127469	Tupaia belangeri	89.15	0.00e+00	680.00
IUUC-Ttr-128252	Tursiops truncatus	88.44	0.00e+00	717.00
IUUC-Vpa-130173	Vicugna pacos	80.47	1.00e-155	542.00
IUUC-Xtr-131803	Xenopus tropicalis	85.39	0.00e+00	704.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence