iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.80e-09	36.5	17	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliq 66
            flC++   + + P+ lp+ + + +++I +wla++++ cP +r++++ +++v  + lr++i 
   Q: 17   NFLCSVCHGVLKRPMRLPCSHIFCKKCIFQWLARQNT-CPCCRKEVKRRKMVQVNKLRKTIG 77
           69**********************************9.*********************996 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSGGYDLNLF ASPPDCNFLC SVCHGVLKRP MRLPCSHIFC KKCIFQWLAR QNTCPCCRKE 60
VKRRKMVQVN KLRKTIGRLQ VKCKNAAAGC LVTCPLAHRK GHQDSCPFEL MACPNEGCTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCCACAGG TGCTGCCAAG TGCAGTCTCC TAAGCCTTTA GTCTCAGTGG AGCTGCCGTC 60
CAGATACAGA TCATGGTGAG CCCCTGGTCT CCACCAGCTC TGAGATTTGT ACTCAATTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR013010--Znf_SIAH
IPR001293--Znf_TRAF

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS51081--ZF_SIAH
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

KEGG

rno:302977

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002248	Ailuropoda melanoleuca	77.73	2.00e-100	358.00
IUUC-Atr-002634	Amborella trichopoda	29.17	2.00e-07	52.80
IUUC-Ago-007863	Ashbya gossypii	46.88	2.00e-06	47.80
IUUC-Afl-008741	Aspergillus flavus	29.60	2.00e-11	61.60
IUUC-Bta-012933	Bos taurus	70.78	1.00e-93	335.00
IUUC-Cja-019617	Callithrix jacchus	74.52	8.00e-88	315.00
IUUC-Cfa-020196	Canis familiaris	74.36	2.00e-98	352.00
IUUC-Cpo-021600	Cavia porcellus	73.42	3.00e-82	297.00
IUUC-Csa-023783	Chlorocebus sabaeus	76.44	1.00e-94	339.00
IUUC-Dre-027766	Danio rerio	40.43	7.00e-48	183.00
IUUC-Dno-029210	Dasypus novemcinctus	73.44	8.00e-95	339.00
IUUC-Dor-030784	Dipodomys ordii	78.54	1.00e-83	302.00
IUUC-Dse-031550	Dothistroma septosporum	45.31	1.00e-09	56.60
IUUC-Eca-034043	Equus caballus	76.03	1.00e-102	365.00
IUUC-Fca-036189	Felis catus	75.31	4.00e-98	350.00
IUUC-Ggo-044555	Gorilla gorilla	77.99	2.00e-89	321.00
IUUC-Hsa-046097	Homo sapiens	77.73	4.00e-84	303.00
IUUC-Itr-048127	Ictidomys tridecemlineatus	79.92	6.00e-88	316.00
IUUC-Kpa-049286	Komagataella pastoris	45.45	1.00e-06	48.10
IUUC-Lch-049574	Latimeria chalumnae	51.21	2.00e-57	214.00
IUUC-Loc-052061	Lepisosteus oculatus	54.10	3.00e-36	143.00
IUUC-Laf-053951	Loxodonta africana	77.03	4.00e-85	307.00
IUUC-Mcc-055550	Macaca mulatta	77.97	3.00e-85	308.00
IUUC-Mmr-061238	Microcebus murinus	79.92	7.00e-91	326.00
IUUC-Mdo-062616	Monodelphis domestica	69.38	3.00e-77	281.00
IUUC-Mmu-063267	Mus musculus	86.61	2.00e-104	370.00
IUUC-Mpu-065982	Mustela putorius furo	74.79	1.00e-97	348.00
IUUC-Mlu-068169	Myotis lucifugus	67.74	2.00e-79	288.00
IUUC-Ncr-068907	Neurospora crassa	33.33	2.00e-07	51.60
IUUC-Nle-069905	Nomascus leucogenys	76.44	5.00e-82	296.00
IUUC-Oar-089320	Ovis aries	68.05	2.00e-90	324.00
IUUC-Ptr-091262	Pan troglodytes	77.03	8.00e-88	316.00
IUUC-Pan-092613	Papio anubis	77.88	1.00e-84	305.00
IUUC-Pab-098534	Pongo abelii	79.05	1.00e-85	309.00
IUUC-Pva-103027	Pteropus vampyrus	75.11	6.00e-95	340.00
IUUC-Sce-106136	Saccharomyces cerevisiae	43.59	2.00e-07	50.80
IUUC-Sha-106717	Sarcophilus harrisii	69.90	5.00e-77	280.00
IUUC-Ssc-115651	Sus scrofa	76.80	1.00e-81	295.00
IUUC-Tbe-127330	Tupaia belangeri	74.67	4.00e-87	313.00
IUUC-Ttr-128564	Tursiops truncatus	74.47	8.00e-90	322.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence