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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-045824
UUCD1 version UUC-HoS-00921
Ensembl Protein ID ENSP00000301724.10
UniProt Accession A0A0A0MR05; A0A0A0MR05_HUMAN
Genbank Protein ID ENSP00000301724
Protein Name Target of rapamycin complex subunit LST8
Genbank Nucleotide ID AC009065
Gene Name MLST8
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000167965.17 ENST00000564088.5 ENSP00000457870.1
ENSG00000167965.17 ENST00000382450.8 ENSP00000371888.4
ENSG00000167965.17 ENST00000570224.5 ENSP00000454629.1
ENSG00000167965.17 ENST00000567623.6 ENSP00000455850.1
ENSG00000167965.17 ENST00000562352.5 ENSP00000456944.1
ENSG00000167965.17 ENST00000563107.5 ENSP00000455475.1
ENSG00000167965.17 ENST00000567282.5 ENSP00000459612.1
ENSG00000167965.17 ENST00000301724.14 ENSP00000301724.10
ENSG00000167965.17 ENST00000566835.5 ENSP00000455458.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
circBaseCircNetmiRTarBasemicroRNA
TRANSFACmiRWalkTargetScanmiRNAMap
miRcodeRAID2
Protein-protein Interaction
iRefIndexHINTInWeb_IM
Disease-associated Variation
OMIM
Post-translational Modifications (PTMs)
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.30e-26 92.4 219 249
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           Ht     ++f +d tll+++s D t+k+W++
   Q: 219  HTRYALQCRFsPDsTLLATCSADQTCKIWRT 249
           888888999**999***************96 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MNTSPGTVGS DPVILATAGY DHTVRFWQAH SGICTRTVQH QDSQVNALEV TPDRSMIAAA 60
GYQHIRMYDL NSNNPNPIIS YDGVNKNIAS VGFHEDGRWM YTGGEDCTAR IWDLRSRNLQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045824|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTAATCCCAG CACTTTGGGA GGCTGAGGTA GGCGGATCAC TTGAGGTCAG GAGTTTGAGA 60
CCAGCCTTGC GAACATGGTG AAATCCCGTC TCCACTAAAA ATACAAAAAT CAGCCAGGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045824|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000595 Aegilops tauschii 48.04 2.00e-72 265.00
IUUC-Aml-001813 Ailuropoda melanoleuca 98.26 6.00e-171 593.00
IUUC-Atr-002512 Amborella trichopoda 46.26 7.00e-69 254.00
IUUC-Apl-003495 Anas platyrhynchos 89.02 1.00e-129 456.00
IUUC-Aca-004613 Anolis carolinensis 93.40 1.00e-164 572.00
IUUC-Aly-006340 Arabidopsis lyrata 44.77 6.00e-69 254.00
IUUC-Ath-007273 Arabidopsis thaliana 44.40 3.00e-68 251.00
IUUC-Ago-007737 Ashbya gossypii 45.68 2.00e-69 255.00
IUUC-Acl-008090 Aspergillus clavatus 47.46 7.00e-60 224.00
IUUC-Afl-008490 Aspergillus flavus 41.84 1.00e-40 160.00
IUUC-Afu-009060 Aspergillus fumigatus 45.98 5.00e-53 201.00
IUUC-Ani-009251 Aspergillus nidulans 47.88 5.00e-60 224.00
IUUC-Ang-009528 Aspergillus niger 44.83 2.00e-63 236.00
IUUC-Aor-010005 Aspergillus oryzae 43.12 1.00e-56 213.00
IUUC-Ate-010423 Aspergillus terreus 47.88 5.00e-60 224.00
IUUC-Ame-011752 Astyanax mexicanus 91.67 1.00e-162 565.00
IUUC-Bgr-012299 Blumeria graminis 41.16 6.00e-58 217.00
IUUC-Bta-013007 Bos taurus 98.26 3.00e-171 594.00
IUUC-Bci-013987 Botrytis cinerea 43.39 3.00e-67 248.00
IUUC-Bdi-014082 Brachypodium distachyon 47.69 4.00e-72 264.00
IUUC-Bol-015088 Brassica oleracea 45.13 7.00e-69 253.00
IUUC-Bra-016682 Brassica rapa 38.67 1.00e-56 213.00
IUUC-Cel-018473 Caenorhabditis elegans 25.41 1.00e-30 127.00
IUUC-Cja-019216 Callithrix jacchus 98.69 1.00e-134 472.00
IUUC-Cfa-021229 Canis familiaris 98.61 5.00e-172 596.00
IUUC-Cpo-022270 Cavia porcellus 98.96 2.00e-172 598.00
IUUC-Cre-022742 Chlamydomonas reinhardtii 46.81 5.00e-72 264.00
IUUC-Csa-023275 Chlorocebus sabaeus 98.96 2.00e-172 598.00
IUUC-Cin-025588 Ciona intestinalis 62.14 5.00e-111 394.00
IUUC-Csv-026252 Ciona savignyi 63.35 3.00e-113 401.00
IUUC-Cgl-026418 Colletotrichum gloeosporioides 45.20 8.00e-65 240.00
IUUC-Cne-027013 Cryptococcus neoformans 41.58 2.00e-59 222.00
IUUC-Cme-027131 Cyanidioschyzon merolae 31.33 4.00e-42 165.00
IUUC-Dre-028424 Danio rerio 91.32 4.00e-162 563.00
IUUC-Dno-029327 Dasypus novemcinctus 98.61 8.00e-172 595.00
IUUC-Dor-030186 Dipodomys ordii 99.38 2.00e-93 335.00
IUUC-Dse-031475 Dothistroma septosporum 42.95 8.00e-63 234.00
IUUC-Dme-031826 Drosophila melanogaster 48.08 2.00e-80 292.00
IUUC-Ete-032252 Echinops telfairi 84.08 4.00e-139 487.00
IUUC-Eca-034067 Equus caballus 96.00 1.00e-127 448.00
IUUC-Fca-035989 Felis catus 98.26 2.00e-171 594.00
IUUC-Fal-036637 Ficedula albicollis 93.06 5.00e-165 573.00
IUUC-Fox-038066 Fusarium oxysporum 46.26 4.00e-68 251.00
IUUC-Fso-038288 Fusarium solani 43.77 3.00e-62 231.00
IUUC-Gmo-039477 Gadus morhua 92.23 5.00e-161 560.00
IUUC-Ggr-039990 Gaeumannomyces graminis 45.61 3.00e-66 245.00
IUUC-Gga-040890 Gallus gallus 93.06 7.00e-165 573.00
IUUC-Gac-041502 Gasterosteus aculeatus 91.32 6.00e-162 563.00
IUUC-Gma-042985 Glycine max 46.62 2.00e-69 256.00
IUUC-Ggo-045629 Gorilla gorilla 98.62 1.00e-171 595.00
IUUC-Hvu-047767 Hordeum vulgare 47.69 4.00e-72 265.00
IUUC-Itr-047932 Ictidomys tridecemlineatus 98.96 2.00e-172 598.00
IUUC-Kpa-049173 Komagataella pastoris 44.60 1.00e-69 256.00
IUUC-Lch-049703 Latimeria chalumnae 93.06 1.00e-164 572.00
IUUC-Lpe-050744 Leersia perrieri 45.61 4.00e-67 248.00
IUUC-Loc-052507 Lepisosteus oculatus 91.32 1.00e-161 562.00
IUUC-Lma-053084 Leptosphaeria maculans 43.30 5.00e-60 224.00
IUUC-Laf-053595 Loxodonta africana 96.88 4.00e-169 587.00
IUUC-Mcc-055634 Macaca mulatta 93.97 4.00e-174 603.00
IUUC-Meu-055925 Macropus eugenii 87.54 3.00e-168 584.00
IUUC-Mor-057131 Magnaporthe oryzae 42.81 3.00e-66 245.00
IUUC-Mpo-057524 Magnaporthe poae 45.26 3.00e-66 245.00
IUUC-Mtr-057980 Medicago truncatula 46.62 7.00e-70 257.00
IUUC-Mla-059082 Melampsora laricipopulina 37.66 2.00e-50 192.00
IUUC-Mga-059552 Meleagris gallopavo 90.61 2.00e-131 461.00
IUUC-Mvi-060504 Microbotryum violaceum 42.16 4.00e-60 226.00
IUUC-Mdo-062886 Monodelphis domestica 94.44 9.00e-166 575.00
IUUC-Mmu-063477 Mus musculus 97.22 7.00e-170 589.00
IUUC-Mac-065439 Musa acuminata 46.98 2.00e-70 259.00
IUUC-Mpu-066708 Mustela putorius furo 98.61 1.00e-171 595.00
IUUC-Mlu-067311 Myotis lucifugus 94.98 5.00e-168 583.00
IUUC-Nfi-068294 Neosartorya fischeri 45.81 2.00e-53 202.00
IUUC-Ncr-068811 Neurospora crassa 43.42 6.00e-63 234.00
IUUC-Nle-069632 Nomascus leucogenys 99.31 5.00e-173 599.00
IUUC-Opr-071128 Ochotona princeps 96.34 3.00e-109 387.00
IUUC-Ont-071494 Oreochromis niloticus 92.36 4.00e-163 567.00
IUUC-Oan-073298 Ornithorhynchus anatinus 92.05 1.00e-81 295.00
IUUC-Ocu-073983 Oryctolagus cuniculus 98.61 1.00e-171 595.00
IUUC-Oba-076001 Oryza barthii 44.56 7.00e-66 243.00
IUUC-Obr-076833 Oryza brachyantha 45.91 5.00e-69 254.00
IUUC-Ogl-077680 Oryza glaberrima 45.91 3.00e-69 255.00
IUUC-Ogu-078086 Oryza glumaepatula 44.56 7.00e-66 244.00
IUUC-Oin-079336 Oryza indica 45.91 3.00e-69 255.00
IUUC-Olo-080368 Oryza longistaminata 42.13 2.00e-52 198.00
IUUC-Oni-083046 Oryza nivara 44.56 6.00e-66 244.00
IUUC-Opu-084173 Oryza punctata 44.56 7.00e-66 243.00
IUUC-Oru-084599 Oryza rufipogon 44.56 7.00e-66 243.00
IUUC-Osa-086193 Oryza sativa 45.91 3.00e-69 255.00
IUUC-Ola-087216 Oryzias latipes 91.67 7.00e-163 566.00
IUUC-Olu-087852 Ostreococcus lucimarinus 44.77 2.00e-67 249.00
IUUC-Oga-088840 Otolemur garnettii 98.28 3.00e-171 593.00
IUUC-Oar-089294 Ovis aries 97.92 3.00e-170 590.00
IUUC-Ptr-090565 Pan troglodytes 99.31 5.00e-173 599.00
IUUC-Pan-092175 Papio anubis 98.96 2.00e-172 598.00
IUUC-Psi-093180 Pelodiscus sinensis 93.13 7.00e-133 466.00
IUUC-Pma-094705 Petromyzon marinus 81.94 4.00e-148 517.00
IUUC-Pno-095001 Phaeosphaeria nodorum 40.49 3.00e-50 191.00
IUUC-Ppa-095628 Physcomitrella patens 47.33 3.00e-71 261.00
IUUC-Pfo-097128 Poecilia formosa 91.32 1.00e-162 565.00
IUUC-Pab-098386 Pongo abelii 99.31 5.00e-173 599.00
IUUC-Pop-099064 Populus trichocarpa 46.62 5.00e-70 258.00
IUUC-Pca-100971 Procavia capensis 95.99 7.00e-172 596.00
IUUC-Ppe-101871 Prunus persica 46.62 1.00e-69 256.00
IUUC-Pva-102230 Pteropus vampyrus 76.55 5.00e-132 463.00
IUUC-Pgr-103511 Puccinia graminis 39.29 2.00e-52 199.00
IUUC-Ptt-103882 Puccinia triticina 35.78 1.00e-49 190.00
IUUC-Pte-104402 Pyrenophora teres 44.18 8.00e-61 227.00
IUUC-Pyt-104448 Pyrenophora triticirepentis 44.18 9.00e-61 227.00
IUUC-Rno-104880 Rattus norvegicus 97.22 3.00e-170 590.00
IUUC-Sce-106266 Saccharomyces cerevisiae 45.68 3.00e-70 258.00
IUUC-Sha-106966 Sarcophilus harrisii 94.44 9.00e-166 575.00
IUUC-Sja-107797 Schizosaccharomyces japonicus 45.49 2.00e-70 259.00
IUUC-Spo-108366 Schizosaccharomyces pombe 43.68 2.00e-69 256.00
IUUC-Smo-108749 Selaginella moellendorffii 46.10 7.00e-68 250.00
IUUC-Sit-110807 Setaria italica 47.69 3.00e-71 261.00
IUUC-Sly-111879 Solanum lycopersicum 40.69 9.00e-39 153.00
IUUC-Sbi-114551 Sorghum bicolor 47.69 4.00e-71 261.00
IUUC-Sre-114962 Sporisorium reilianum 36.92 2.00e-57 216.00
IUUC-Ssc-115363 Sus scrofa 97.93 1.00e-170 592.00
IUUC-Tgu-116695 Taeniopygia guttata 74.65 5.00e-118 417.00
IUUC-Tru-117999 Takifugu rubripes 89.66 6.00e-160 556.00
IUUC-Tni-119973 Tetraodon nigroviridis 90.28 2.00e-161 561.00
IUUC-Tca-121688 Theobroma cacao 46.81 7.00e-70 257.00
IUUC-Tre-122158 Trichoderma reesei 41.64 1.00e-62 233.00
IUUC-Tvi-122511 Trichoderma virens 44.21 2.00e-64 239.00
IUUC-Tae-124124 Triticum aestivum 48.04 3.00e-72 265.00
IUUC-Tur-126228 Triticum urartu 50.20 1.00e-68 253.00
IUUC-Tme-127100 Tuber melanosporum 47.65 1.00e-73 270.00
IUUC-Ttr-128216 Tursiops truncatus 98.98 1.00e-54 206.00
IUUC-Uma-129358 Ustilago maydis 37.93 6.00e-59 221.00
IUUC-Vda-129756 Verticillium dahliae 45.00 2.00e-66 245.00
IUUC-Vvi-131581 Vitis vinifera 45.55 5.00e-68 251.00
IUUC-Xtr-132363 Xenopus tropicalis 89.93 5.00e-159 553.00
IUUC-Xma-133857 Xiphophorus maculatus 91.32 1.00e-162 565.00
IUUC-Yli-134368 Yarrowia lipolytica 44.96 4.00e-68 251.00
IUUC-Zma-135854 Zea mays 47.69 3.00e-71 261.00
Created Date 25-Jun-2017

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