iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090731

UUCD1 version

UUC-PaT-00294

Ensembl Protein ID

ENSPTRP00000013118.3

UniProt Accession

H2QAF1; H2QAF1_PANTR

Genbank Protein ID

JAA09497.1; JAA09498.1; JAA13562.1; JAA27192.1; JAA27193.1; JAA41818.1; JAA41819.1

Protein Name

THO complex 6 homolog

Genbank Nucleotide ID

AACZ03103582; GABC01001840; GABF01008583; GABD01005908; GABD01005907; GABE01002921; GABE01002920

Gene Name

THOC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000007680.5	ENSPTRT00000014161.3	ENSPTRP00000013118.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.60e-14	51.1	166	205

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gHtd ++cla+   ++ ++sG+ Dg +++WDlrt + +++
   Q: 166  GHTDYIHCLALreRSPEVLSGGEDGAVRLWDLRTAKEVQT 205
           8**********98559******************998875 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MERAVPLAVP LGQTEVFQAL QRLHMTIFSQ SVSPCGKFLA AGNNYGQIAI FSLSAALSSE 60
AKEESKKPVV TFQAHDGPVY SMVSTDRHLL SAGDGEVKAW LWAEMLKKGC KELWRRQPPY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCACAGCG GCGAGGTTCT GCGCGGGCGC GGAAGACGGG CGGCGCGTGG CGGAAGGCAG 60
GCTTGCTCCT CGGGGTGGGG GAGGGTATCC GGCTTAAGGG GGCTGCGGTG GACGCCACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0000784--C:nuclear chromosome, telomeric region
GO:0016607--C:nuclear speck
GO:0000445--C:THO complex part of transcription export complex
GO:0007417--P:central nervous system development
GO:0043066--P:negative regulation of apoptotic process
GO:0046784--P:viral mRNA export from host cell nucleus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001101	Aegilops tauschii	30.24	5.00e-30	125.00
IUUC-Aml-001693	Ailuropoda melanoleuca	97.07	0.00e+00	629.00
IUUC-Atr-002699	Amborella trichopoda	29.20	3.00e-23	102.00
IUUC-Aca-004231	Anolis carolinensis	70.64	3.00e-127	447.00
IUUC-Aly-006385	Arabidopsis lyrata	30.53	2.00e-28	119.00
IUUC-Ath-006723	Arabidopsis thaliana	29.70	1.00e-28	120.00
IUUC-Ame-010813	Astyanax mexicanus	65.58	8.00e-90	322.00
IUUC-Bta-013458	Bos taurus	96.19	8.00e-180	622.00
IUUC-Bdi-014935	Brachypodium distachyon	29.84	5.00e-30	125.00
IUUC-Bol-015442	Brassica oleracea	29.75	6.00e-29	121.00
IUUC-Bra-017807	Brassica rapa	30.41	7.00e-29	120.00
IUUC-Cja-019061	Callithrix jacchus	98.54	0.00e+00	634.00
IUUC-Cfa-021146	Canis familiaris	97.65	0.00e+00	632.00
IUUC-Cpo-022512	Cavia porcellus	96.48	0.00e+00	628.00
IUUC-Csa-023055	Chlorocebus sabaeus	98.53	0.00e+00	643.00
IUUC-Cho-024693	Choloepus hoffmanni	96.39	8.00e-100	355.00
IUUC-Cin-025181	Ciona intestinalis	36.34	9.00e-58	216.00
IUUC-Csv-025852	Ciona savignyi	34.93	2.00e-49	189.00
IUUC-Dre-028221	Danio rerio	60.25	2.00e-119	421.00
IUUC-Dno-029200	Dasypus novemcinctus	91.53	5.00e-89	319.00
IUUC-Dor-030863	Dipodomys ordii	95.60	3.00e-179	620.00
IUUC-Dme-032016	Drosophila melanogaster	28.75	2.00e-37	149.00
IUUC-Eca-034363	Equus caballus	97.36	0.00e+00	632.00
IUUC-Fca-036546	Felis catus	97.07	0.00e+00	631.00
IUUC-Gmo-038513	Gadus morhua	57.23	2.00e-109	388.00
IUUC-Gac-042606	Gasterosteus aculeatus	57.76	8.00e-113	399.00
IUUC-Gma-043171	Glycine max	28.52	2.00e-32	133.00
IUUC-Ggo-044877	Gorilla gorilla	99.71	0.00e+00	647.00
IUUC-Hsa-045813	Homo sapiens	99.71	0.00e+00	647.00
IUUC-Hvu-047782	Hordeum vulgare	31.08	1.00e-20	92.40
IUUC-Itr-047876	Ictidomys tridecemlineatus	97.36	0.00e+00	632.00
IUUC-Lch-049506	Latimeria chalumnae	64.44	3.00e-120	424.00
IUUC-Lpe-051203	Leersia perrieri	29.83	8.00e-25	107.00
IUUC-Loc-052451	Lepisosteus oculatus	51.23	8.00e-90	323.00
IUUC-Laf-053864	Loxodonta africana	95.60	1.00e-178	618.00
IUUC-Mcc-055705	Macaca mulatta	90.72	3.00e-158	550.00
IUUC-Meu-055926	Macropus eugenii	91.13	1.00e-157	548.00
IUUC-Mtr-058556	Medicago truncatula	29.13	1.00e-32	133.00
IUUC-Mmr-060836	Microcebus murinus	97.65	0.00e+00	635.00
IUUC-Mdo-062534	Monodelphis domestica	91.13	1.00e-156	545.00
IUUC-Mmu-063560	Mus musculus	95.60	3.00e-179	620.00
IUUC-Mac-065134	Musa acuminata	29.20	2.00e-26	113.00
IUUC-Mpu-066031	Mustela putorius furo	98.24	0.00e+00	636.00
IUUC-Mlu-068051	Myotis lucifugus	93.26	5.00e-172	596.00
IUUC-Nle-069080	Nomascus leucogenys	99.12	0.00e+00	642.00
IUUC-Opr-070787	Ochotona princeps	92.08	2.00e-169	587.00
IUUC-Ont-071952	Oreochromis niloticus	56.52	3.00e-111	394.00
IUUC-Oan-073334	Ornithorhynchus anatinus	86.54	2.00e-119	421.00
IUUC-Oba-075175	Oryza barthii	30.39	1.00e-25	110.00
IUUC-Obr-076393	Oryza brachyantha	30.94	1.00e-25	110.00
IUUC-Ogl-077603	Oryza glaberrima	35.59	7.00e-19	87.40
IUUC-Ogu-078211	Oryza glumaepatula	30.39	1.00e-25	110.00
IUUC-Oin-079554	Oryza indica	30.39	6.00e-26	111.00
IUUC-Olo-080922	Oryza longistaminata	32.48	3.00e-23	102.00
IUUC-Ome-081127	Oryza meridionalis	23.76	2.00e-12	67.40
IUUC-Oni-082376	Oryza nivara	30.39	1.00e-25	110.00
IUUC-Opu-083163	Oryza punctata	29.83	3.00e-25	108.00
IUUC-Oru-084311	Oryza rufipogon	30.39	2.00e-25	109.00
IUUC-Osa-085762	Oryza sativa	35.59	1.00e-18	87.00
IUUC-Oga-088804	Otolemur garnettii	95.89	2.00e-180	624.00
IUUC-Oar-090095	Ovis aries	95.60	6.00e-179	619.00
IUUC-Pan-092595	Papio anubis	99.12	0.00e+00	640.00
IUUC-Psi-093866	Pelodiscus sinensis	70.53	5.00e-118	417.00
IUUC-Pma-094236	Petromyzon marinus	59.88	3.00e-117	414.00
IUUC-Pfo-096095	Poecilia formosa	56.52	6.00e-107	380.00
IUUC-Pab-098385	Pongo abelii	99.12	0.00e+00	645.00
IUUC-Pop-099433	Populus trichocarpa	27.24	3.00e-29	122.00
IUUC-Pca-101119	Procavia capensis	96.35	1.00e-117	415.00
IUUC-Ppe-101677	Prunus persica	28.63	5.00e-27	115.00
IUUC-Pva-102726	Pteropus vampyrus	96.77	0.00e+00	628.00
IUUC-Rno-105576	Rattus norvegicus	96.19	3.00e-180	624.00
IUUC-Sha-106774	Sarcophilus harrisii	91.74	1.00e-158	551.00
IUUC-Sit-109988	Setaria italica	28.12	5.00e-28	118.00
IUUC-Sly-110864	Solanum lycopersicum	30.56	2.00e-29	123.00
IUUC-Sar-113060	Sorex araneus	87.45	5.00e-129	452.00
IUUC-Sbi-114699	Sorghum bicolor	29.43	8.00e-29	120.00
IUUC-Ssc-116445	Sus scrofa	97.36	0.00e+00	633.00
IUUC-Tru-117834	Takifugu rubripes	57.27	1.00e-115	409.00
IUUC-Tni-119651	Tetraodon nigroviridis	57.76	2.00e-114	405.00
IUUC-Tca-121318	Theobroma cacao	27.42	5.00e-28	118.00
IUUC-Tae-124184	Triticum aestivum	30.24	5.00e-30	125.00
IUUC-Tur-126226	Triticum urartu	30.39	1.00e-26	113.00
IUUC-Tbe-128079	Tupaia belangeri	81.27	3.00e-107	380.00
IUUC-Ttr-128391	Tursiops truncatus	92.11	8.00e-170	589.00
IUUC-Vvi-131148	Vitis vinifera	27.02	7.00e-25	107.00
IUUC-Xtr-132743	Xenopus tropicalis	62.31	1.00e-117	416.00
IUUC-Xma-133722	Xiphophorus maculatus	56.83	1.00e-111	395.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence