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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063602
UUCD1 version UUC-MuM-00519
Ensembl Protein ID ENSMUSP00000140303.1
UniProt Accession Q6PB97; Q7TSH0; Q8BIB4; FXL19_MOUSE
Genbank Protein ID BAC27400.1; AAH53109.1; AAH59812.1
Protein Name F-box/LRR-repeat protein 19; F-box and leucine-rich repeat protein 19
Genbank Nucleotide ID AK031431; BC053109; BC059812
Gene Name Fbxl19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000030811.14 ENSMUST00000186207.6 ENSMUSP00000140303.1
ENSMUSG00000030811.14 ENSMUST00000188580.2 ENSMUSP00000140021.1
ENSMUSG00000030811.14 ENSMUST00000206893.1 ENSMUSP00000145616.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IIDPINAHINTMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 2.20e-12 48.1 66 130
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggede......k....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrs 53
           +vCl+Cge+g+++      +    sl+eC++C+e++Hp+Clk+      +++e pn+  w+Cp+C++
   Q: 66   AVCLLCGEAGKEDtvegedEkfslSLMECTICNEIVHPGCLKMGkaegvINSEIPNC--WECPRCTQ 130
           79*********9977776516779*******************99************..******97 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
 Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Protein Sequence
(Fasta)
MSSSSRGPGA GARRRRTRCR RCRACVRTEC GDCHFCRDMK KFGGPGRMKQ SCLLRQCTAP 60
VLPHTAVCLL CGEAGKEDTV EGEDEKFSLS LMECTICNEI VHPGCLKMGK AEGVINSEIP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063602|E3,PHD|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTGCTGGGTA GAGATGGTTG GAAGACTCAG ATGAGGACTG AAGAGGGAGG GGTGGGGGTT 60
AAGATGGGGG TAGCCTACTC GTCAATTTTC TTTTCGCAGA AGCTAACTGT CCGGCATGAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063602|E3,PHD|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0433--Leucine-rich repeat
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR019786--Zinc_finger_PHD-type_CS
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51058--ZF_CXXC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF00646--F-box
PF16866--PHD_4
PF02008--zf-CXXC
SMART

SM00256--FBOX
SM00367--LRR_CC
SM00249--PHD
Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0003677--F:DNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
KEGG mmu:233902
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001680 Ailuropoda melanoleuca 95.51 0.00e+00 907.00
IUUC-Aca-004456 Anolis carolinensis 62.22 0.00e+00 702.00
IUUC-Ame-010726 Astyanax mexicanus 60.33 9.00e-97 348.00
IUUC-Bta-012874 Bos taurus 97.21 0.00e+00 989.00
IUUC-Cja-019918 Callithrix jacchus 96.90 0.00e+00 985.00
IUUC-Cfa-020078 Canis familiaris 97.21 0.00e+00 956.00
IUUC-Cpo-021482 Cavia porcellus 97.21 0.00e+00 961.00
IUUC-Csa-023072 Chlorocebus sabaeus 97.21 0.00e+00 989.00
IUUC-Dno-029532 Dasypus novemcinctus 88.92 0.00e+00 835.00
IUUC-Dor-030932 Dipodomys ordii 96.90 0.00e+00 954.00
IUUC-Eca-033707 Equus caballus 97.37 0.00e+00 967.00
IUUC-Eeu-034841 Erinaceus europaeus 94.18 4.00e-155 541.00
IUUC-Fca-036214 Felis catus 95.98 0.00e+00 952.00
IUUC-Gmo-039631 Gadus morhua 62.61 3.00e-83 302.00
IUUC-Ggo-045362 Gorilla gorilla 96.94 0.00e+00 895.00
IUUC-Hsa-046325 Homo sapiens 97.37 0.00e+00 957.00
IUUC-Itr-048488 Ictidomys tridecemlineatus 97.21 0.00e+00 957.00
IUUC-Lch-049586 Latimeria chalumnae 60.99 2.00e-113 403.00
IUUC-Laf-053994 Loxodonta africana 96.12 0.00e+00 753.00
IUUC-Mcc-054810 Macaca mulatta 97.37 0.00e+00 957.00
IUUC-Meu-056447 Macropus eugenii 98.49 1.00e-144 506.00
IUUC-Mmr-060961 Microcebus murinus 97.06 0.00e+00 986.00
IUUC-Mpu-066470 Mustela putorius furo 97.37 0.00e+00 953.00
IUUC-Mlu-068033 Myotis lucifugus 94.78 0.00e+00 831.00
IUUC-Nle-069352 Nomascus leucogenys 97.06 0.00e+00 951.00
IUUC-Opr-070370 Ochotona princeps 96.93 0.00e+00 887.00
IUUC-Ont-071246 Oreochromis niloticus 62.18 1.00e-92 334.00
IUUC-Ocu-074480 Oryctolagus cuniculus 96.28 0.00e+00 940.00
IUUC-Oga-088335 Otolemur garnettii 97.06 0.00e+00 957.00
IUUC-Oar-090135 Ovis aries 84.31 6.00e-132 464.00
IUUC-Ptr-091271 Pan troglodytes 97.87 2.00e-178 618.00
IUUC-Pan-092365 Papio anubis 96.90 0.00e+00 986.00
IUUC-Pab-097786 Pongo abelii 90.71 0.00e+00 847.00
IUUC-Pca-100857 Procavia capensis 94.81 3.00e-162 565.00
IUUC-Pva-102613 Pteropus vampyrus 97.52 0.00e+00 970.00
IUUC-Rno-106113 Rattus norvegicus 99.54 0.00e+00 1011.00
IUUC-Sha-106914 Sarcophilus harrisii 86.86 0.00e+00 825.00
IUUC-Ssc-115503 Sus scrofa 96.76 0.00e+00 932.00
IUUC-Tru-118079 Takifugu rubripes 64.73 2.00e-92 333.00
IUUC-Tni-120597 Tetraodon nigroviridis 64.00 4.00e-89 322.00
IUUC-Tur-126327 Triticum urartu 35.06 4.00e-04 39.30
IUUC-Tbe-127536 Tupaia belangeri 89.15 0.00e+00 842.00
IUUC-Ttr-128198 Tursiops truncatus 97.32 0.00e+00 936.00
IUUC-Xtr-132076 Xenopus tropicalis 50.18 5.00e-64 238.00
Created Date 25-Jun-2017

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