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Tag Content
iUUCD ID IUUC-Mdo-062983
Ensembl Protein ID ENSMODP00000016381.2
UniProt Accession F7EXR1; F7EXR1_MONDO
Protein Name Uncharacterized protein
Gene Name NOD2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMODG00000013087.2 ENSMODT00000016683.2 ENSMODP00000016381.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/CARD 68.02 0.00e+00 1126.00 IUUC-Hsa-046093
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Monodelphis domestica
Protein Sequence
(Fasta)
MERVSTSSSK LMYPTLARRL LDFAKVKDNG VAQFLLQHIL QLPVLPVPLP DVTACKKYTA 60
KLKATVSAQS RFLSTYDGTE NLCLENIYTE NILEIRKNLS LGVPSQKGHD TLELAEIFNH 120
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Protein Fasta Sequence



>IUUC-Mdo-062983|UBD,CARD|Monodelphis domestica
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Nucleotide Sequence
(Fasta)
CGGCGCTGGC GCTGCCAGAA CTTTGGTGGC AGAGCCCAGG CTGCTGGAGG GGCAGACAGG 60
AGCAGGCGGA GTCAATGGCC TGAGTGATCT TGCAGGTGTG TGGAAGGGTC GGGGAGAGGG 120
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Nucleotide Fasta Sequence



>IUUC-Mdo-062983|UBD,CARD|Monodelphis domestica
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase

PROSITE

PS51450--LRR
PS50837--NACHT

Pfam

PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0009986--C:cell surface
GO:0008180--C:COP9 signalosome
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0031982--C:vesicle
GO:0005524--F:ATP binding
GO:0032500--F:muramyl dipeptide binding
GO:0042834--F:peptidoglycan binding
GO:0071225--P:cellular response to muramyl dipeptide
GO:0002374--P:cytokine secretion involved in immune response
GO:0042742--P:defense response to bacterium
GO:0016045--P:detection of bacterium
GO:0032498--P:detection of muramyl dipeptide
GO:0045087--P:innate immune response
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0070431--P:nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0050871--P:positive regulation of B cell activation
GO:1900017--P:positive regulation of cytokine production involved in inflammatory response
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050718--P:positive regulation of interleukin-1 beta secretion
GO:0032740--P:positive regulation of interleukin-17 production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:0002830--P:positive regulation of type 2 immune response

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001822 Ailuropoda melanoleuca 67.13 0.00e+00 1020.00
IUUC-Ame-011021 Astyanax mexicanus 48.61 0.00e+00 808.00
IUUC-Bta-013241 Bos taurus 68.52 0.00e+00 1145.00
IUUC-Cja-019633 Callithrix jacchus 61.99 0.00e+00 772.00
IUUC-Cfa-020039 Canis familiaris 67.83 0.00e+00 1120.00
IUUC-Cpo-022337 Cavia porcellus 64.93 0.00e+00 1041.00
IUUC-Csa-023906 Chlorocebus sabaeus 67.09 0.00e+00 1125.00
IUUC-Dre-027568 Danio rerio 48.73 0.00e+00 764.00
IUUC-Dno-029098 Dasypus novemcinctus 66.82 0.00e+00 1058.00
IUUC-Dor-031102 Dipodomys ordii 72.46 9.00e-159 554.00
IUUC-Ete-032943 Echinops telfairi 66.46 0.00e+00 945.00
IUUC-Eca-034310 Equus caballus 66.90 0.00e+00 1125.00
IUUC-Eeu-034589 Erinaceus europaeus 69.37 2.00e-136 479.00
IUUC-Fca-036252 Felis catus 72.70 1.00e-155 544.00
IUUC-Gac-041442 Gasterosteus aculeatus 47.99 0.00e+00 735.00
IUUC-Ggo-044861 Gorilla gorilla 68.37 0.00e+00 1093.00
IUUC-Hsa-046093 Homo sapiens 68.02 0.00e+00 1088.00
IUUC-Itr-048543 Ictidomys tridecemlineatus 66.35 0.00e+00 1007.00
IUUC-Lch-049454 Latimeria chalumnae 55.90 0.00e+00 956.00
IUUC-Laf-053553 Loxodonta africana 69.80 0.00e+00 1041.00
IUUC-Mcc-055772 Macaca mulatta 67.33 0.00e+00 1107.00
IUUC-Meu-056785 Macropus eugenii 82.92 2.00e-139 490.00
IUUC-Mmr-060596 Microcebus murinus 66.74 0.00e+00 1072.00
IUUC-Mmu-063951 Mus musculus 61.38 0.00e+00 1045.00
IUUC-Mpu-066412 Mustela putorius furo 67.36 0.00e+00 1110.00
IUUC-Mlu-067601 Myotis lucifugus 64.23 0.00e+00 1039.00
IUUC-Nle-069913 Nomascus leucogenys 67.67 0.00e+00 1081.00
IUUC-Opr-070999 Ochotona princeps 63.45 0.00e+00 729.00
IUUC-Ont-072512 Oreochromis niloticus 49.60 0.00e+00 818.00
IUUC-Oan-073564 Ornithorhynchus anatinus 65.94 0.00e+00 1001.00
IUUC-Ocu-074837 Oryctolagus cuniculus 67.71 0.00e+00 1085.00
IUUC-Ogu-078061 Oryza glumaepatula 28.92 1.50e+00 29.60
IUUC-Oni-083091 Oryza nivara 26.74 3.30e-01 32.00
IUUC-Ola-086555 Oryzias latipes 49.00 0.00e+00 754.00
IUUC-Oga-088909 Otolemur garnettii 67.25 0.00e+00 1067.00
IUUC-Oar-089315 Ovis aries 67.94 0.00e+00 1095.00
IUUC-Ptr-090542 Pan troglodytes 68.02 0.00e+00 1089.00
IUUC-Pan-092545 Papio anubis 67.21 0.00e+00 1102.00
IUUC-Pma-094167 Petromyzon marinus 32.39 3.00e-62 233.00
IUUC-Ppa-095344 Physcomitrella patens 34.94 8.00e-06 46.20
IUUC-Pfo-096976 Poecilia formosa 48.79 0.00e+00 800.00
IUUC-Pab-098481 Pongo abelii 68.14 0.00e+00 1090.00
IUUC-Pca-100135 Procavia capensis 68.41 0.00e+00 970.00
IUUC-Pva-102127 Pteropus vampyrus 66.40 0.00e+00 1042.00
IUUC-Rno-105783 Rattus norvegicus 64.92 0.00e+00 1038.00
IUUC-Sar-113448 Sorex araneus 61.79 6.00e-164 571.00
IUUC-Tru-118708 Takifugu rubripes 47.24 0.00e+00 717.00
IUUC-Tni-120172 Tetraodon nigroviridis 35.88 1.00e-32 133.00
IUUC-Tca-121582 Theobroma cacao 25.00 2.60e-01 29.30
IUUC-Tbe-127661 Tupaia belangeri 67.86 0.00e+00 662.00
IUUC-Ttr-128318 Tursiops truncatus 60.39 0.00e+00 930.00
IUUC-Vpa-130502 Vicugna pacos 63.13 7.00e-72 265.00
Created Date 25-Jun-2017

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