iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013560

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02048838

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000000120.5	ENSBTAT00000000131.5	ENSBTAP00000000131.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-91	305.9	100	710

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+gNtC+mN+v+QcLsn+  l+e+l     ++ ++   +   +e++++l+ l+++lw+++ +     e+++a++k+  +f+g++q
   Q: 100  QGLKNHGNTCFMNAVVQCLSNTDLLAEFLAL---RRYRA---EPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGAQFQGNAQ 182
           6***************************999...33333...235689***************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +Da Efl +lld+++e+l+ +++ p +++ + + +++s++  +++ + + ++s+++  Fq q++s+++c++c ++s++++pfl +slp+
   Q: 183  HDALEFLLWLLDRVHEDLEGSSRGPGSDKLQPEARKTSENllSPSAPLSMGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPI 271
           ******************988887777777777677766677999999***************************************** PP
   S: 177  pgkeetkke................................................................................ 185
           p ++++ ++                                                                                
   Q: 272  PLRQTRFLSvtlvfpsksqrflriglavpilstvaalrkmvaeeggvspeevilvelypsglqrsffdeedlntiaegdnvyafqapps 360
           ****98888******************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 361  pgqemlsarpsgllvspclaaregqrlslpvhnetsvlilfcnlvgsgqqasrfgppflvredraiswiqlqqcilskvrylmksevpi 449
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 450  qnlgslfsirvvglslacsylspqdsrplchwavdralhlrrpggpphiklavewdvdtkerlfgspqeervqdadsvrrqqqahqqhs 538
           ***************************************************************************************** PP
   S: 186  .slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekq 272
            +l++c++ +tkee+l +++++ c++c+++q+ + kl+l++lP++Li+hLkRf   + +++r+k+++ v+fpl  L+++p++++++++ 
   Q: 539  cTLDECFQFYTKEEQLAQDDAWRCPHCQALQQGVVKLSLWTLPDILIIHLKRF--CQVGERRNKLSTLVKFPLAgLNMAPHVAQRSTSP 625
           *****************************************************..88899************************88887 PP
   S: 273  ke.....................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           k                      +  Y+L+av++H+Gsl++GHY+ay++n  +g+W+ +dDs V+++ e+ev++   + aY+lfY++r
   Q: 626  KAmpgawppswkqpaclptsyppDFLYDLYAVCNHHGSLQGGHYTAYCRNsLDGQWYSYDDSMVEPLLEDEVNT---RGAYILFYQKR 710
           779999999999999******99***************************55788*******************...********985 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MDPSAGAAAE EEPPAPRPRR RRSLRRLFGR FLLALGSRSR LGDSPPRPRP QPQSGHGDGD 60
GEGGFEGKDP AAPGSPGEER PPGPQPQLPA GDAARPPGAQ GLKNHGNTCF MNAVVQCLSN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCCAA GCGCGGGGGC CGCGGCCGAA GAGGAGCCGC CTGCGCCCCG GCCCCGCCGC 60
CGCCGCTCCC TGCGCCGCCT GTTCGGCCGC TTCCTGCTGG CGCTGGGCAG TCGCTCCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	77.25	0.00e+00	1426.00
IUUC-Aca-004436	Anolis carolinensis	52.77	0.00e+00	791.00
IUUC-Ame-011153	Astyanax mexicanus	49.15	0.00e+00	865.00
IUUC-Cja-018737	Callithrix jacchus	77.37	0.00e+00	1514.00
IUUC-Cfa-020347	Canis familiaris	77.84	0.00e+00	1466.00
IUUC-Csa-023656	Chlorocebus sabaeus	79.96	0.00e+00	1553.00
IUUC-Cho-024864	Choloepus hoffmanni	70.45	0.00e+00	877.00
IUUC-Dre-028066	Danio rerio	48.72	0.00e+00	884.00
IUUC-Dno-028855	Dasypus novemcinctus	72.17	0.00e+00	1314.00
IUUC-Dor-030475	Dipodomys ordii	86.29	0.00e+00	697.00
IUUC-Dme-032088	Drosophila melanogaster	37.22	2.00e-110	394.00
IUUC-Eca-034147	Equus caballus	86.33	0.00e+00	1476.00
IUUC-Eeu-034703	Erinaceus europaeus	71.77	4.00e-141	495.00
IUUC-Fca-036550	Felis catus	74.97	0.00e+00	1268.00
IUUC-Gac-042087	Gasterosteus aculeatus	60.56	0.00e+00	850.00
IUUC-Ggo-045171	Gorilla gorilla	80.23	0.00e+00	1555.00
IUUC-Hsa-045961	Homo sapiens	80.10	0.00e+00	1557.00
IUUC-Itr-048673	Ictidomys tridecemlineatus	68.55	1.00e-176	612.00
IUUC-Loc-052852	Lepisosteus oculatus	62.16	0.00e+00	917.00
IUUC-Laf-054033	Loxodonta africana	76.47	0.00e+00	1464.00
IUUC-Mcc-055431	Macaca mulatta	79.67	0.00e+00	1555.00
IUUC-Mmr-061035	Microcebus murinus	81.03	0.00e+00	1546.00
IUUC-Mdo-062172	Monodelphis domestica	66.80	0.00e+00	944.00
IUUC-Mmu-063966	Mus musculus	74.57	0.00e+00	1450.00
IUUC-Mpu-066307	Mustela putorius furo	77.93	0.00e+00	1403.00
IUUC-Nle-070172	Nomascus leucogenys	79.65	0.00e+00	1553.00
IUUC-Opr-070499	Ochotona princeps	70.30	0.00e+00	1321.00
IUUC-Ont-071920	Oreochromis niloticus	51.60	0.00e+00	914.00
IUUC-Ocu-074014	Oryctolagus cuniculus	80.00	0.00e+00	1159.00
IUUC-Ola-086360	Oryzias latipes	60.82	0.00e+00	882.00
IUUC-Oga-088202	Otolemur garnettii	78.83	0.00e+00	1526.00
IUUC-Oar-089819	Ovis aries	94.83	0.00e+00	1865.00
IUUC-Ptr-091076	Pan troglodytes	80.00	0.00e+00	1555.00
IUUC-Pan-092248	Papio anubis	79.48	0.00e+00	1539.00
IUUC-Pfo-096534	Poecilia formosa	58.45	0.00e+00	802.00
IUUC-Pab-098453	Pongo abelii	77.72	0.00e+00	1490.00
IUUC-Pca-100290	Procavia capensis	60.14	0.00e+00	690.00
IUUC-Pva-102317	Pteropus vampyrus	73.55	0.00e+00	1403.00
IUUC-Rno-104948	Rattus norvegicus	73.32	0.00e+00	1320.00
IUUC-Sha-106558	Sarcophilus harrisii	57.53	0.00e+00	1099.00
IUUC-Sar-113105	Sorex araneus	62.45	0.00e+00	1019.00
IUUC-Ssc-115312	Sus scrofa	83.89	0.00e+00	1657.00
IUUC-Tru-117995	Takifugu rubripes	63.52	0.00e+00	901.00
IUUC-Tsy-119325	Tarsius syrichta	73.07	0.00e+00	721.00
IUUC-Tni-120517	Tetraodon nigroviridis	58.73	0.00e+00	861.00
IUUC-Tbe-127439	Tupaia belangeri	64.18	2.00e-122	433.00
IUUC-Ttr-128829	Tursiops truncatus	79.35	0.00e+00	1546.00
IUUC-Vpa-130306	Vicugna pacos	83.88	0.00e+00	660.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence