iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054033

UUCD1 version

UUC-LoA-01084

Ensembl Protein ID

ENSLAFP00000022664.1

UniProt Accession

G3U4A6; G3U4A6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000014238.4	ENSLAFT00000033851.1	ENSLAFP00000022664.1
ENSLAFG00000014238.4	ENSLAFT00000014240.4	ENSLAFP00000011924.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.40e-92	309.6	93	694

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+gNtC+mN+v+QcLsn+  l+e+l     ++ +        +e++++l+ l+++lw+++ +     e+++a++k+ ++f+g++q
   Q: 93   QGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPG------RAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQ 175
           6****************************9955555555......479***************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpke.eeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           +Da Efl +lld+++e+l+ +++  ++ +++ e+++++++ ++  +   ++s+++  Fq q++s+++c++c ++s++++pfl +slp+p
   Q: 176  HDALEFLLWLLDRVHEDLDGSSQRGVSdKLQPETSKHSENLSSTAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIP 264
           ******************775555554055555556666668899999999************************************** PP
   S: 178  gkeetkke................................................................................. 185
            ++++ ++                                                                                 
   Q: 265  LRQTRFLSvtlafpsksqrflrvglavpilstvaalrkmvadegnvpadevilvelhpsgfhrsffddddlnsiaegdnvyafhcpssp 353
           ***98888********************************************************************************* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 354  gqgrrsvhpsglpvsprlaaregqrgnkvlilccnvvgsgqqasrfgppflvredrgiswpqlqqcilskvcylmkreaplqnlgvpfs 442
           ***************************************************************************************** PP
   S: 186  ..................................................................................slqdcLe 192
                                                                                             +l++c++
   Q: 443  irvvglslacsylspqdgrplchwvvdralhlrrpggpphvklavewdscakerlfgslqeervqdaesvwqqqqahqqpscTLDECFQ 531
           ***************************************************************************************** PP
   S: 193  sftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke...... 274
            +tkee+l+++++++c++ck +q+ + kl+l++lP++Li+hLkRf   + +++r+k+++ v+fpl+ L+++p+++ ++++ +       
   Q: 532  FYTKEEQLTQDDAWKCPHCKVLQQGTVKLSLWTLPDILIIHLKRF--CQVGERRNKLSTLVKFPLSgLNMAPHVAPRSTGPQPgsgpwp 618
           *********************************************..88899***********************98877766999999 PP
   S: 275  ..............kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
                         +  Y+L+av++H+Gsl++GHY+ay++n  +g+W+ +dDs+V++++e+ev++   + aY+lfY++r
   Q: 619  swkqptclpngyplDFLYDLYAVCNHHGSLQGGHYTAYCRNsLDGRWYSYDDSTVEPLREDEVNT---RGAYILFYQKR 694
           99999999999999***************************44666*******************...********985 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

AGPGDASAQG PPLPRRRSSL RRLLSRFLLA LGSRARPGAS PLRPGSCNGE GEGGFAHARV 60
PAPSAPGSPG EERQPRPQPQ LPAGDGARPP GAQGLKNHGN TCFMNAVVQC LSNTDLLAEF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGGCCCGG GGGATGCGAG CGCACAGGGG CCGCCCCTGC CCCGCCGCCG CAGCTCCCTA 60
CGCCGCCTGC TCAGCCGCTT CCTGCTGGCT CTGGGCAGCC GCGCCCGCCC GGGGGCTTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	73.25	0.00e+00	1321.00
IUUC-Apl-003186	Anas platyrhynchos	51.02	3.00e-153	536.00
IUUC-Aca-004436	Anolis carolinensis	51.50	0.00e+00	767.00
IUUC-Ame-011153	Astyanax mexicanus	48.40	0.00e+00	838.00
IUUC-Bta-013560	Bos taurus	76.38	0.00e+00	1469.00
IUUC-Cel-018710	Caenorhabditis elegans	26.78	3.00e-45	177.00
IUUC-Cja-018737	Callithrix jacchus	76.73	0.00e+00	1486.00
IUUC-Cfa-020347	Canis familiaris	75.48	0.00e+00	1395.00
IUUC-Csa-023656	Chlorocebus sabaeus	78.70	0.00e+00	1524.00
IUUC-Cho-024864	Choloepus hoffmanni	69.97	0.00e+00	872.00
IUUC-Csv-026086	Ciona savignyi	38.99	3.00e-118	419.00
IUUC-Dre-028066	Danio rerio	48.78	0.00e+00	862.00
IUUC-Dno-028855	Dasypus novemcinctus	71.25	0.00e+00	1346.00
IUUC-Dor-030475	Dipodomys ordii	84.02	0.00e+00	674.00
IUUC-Dme-032088	Drosophila melanogaster	36.76	1.00e-108	388.00
IUUC-Ete-032975	Echinops telfairi	41.51	2.00e-101	363.00
IUUC-Eca-034147	Equus caballus	82.09	0.00e+00	1355.00
IUUC-Eeu-034703	Erinaceus europaeus	70.63	5.00e-130	459.00
IUUC-Fca-036550	Felis catus	71.29	0.00e+00	1184.00
IUUC-Fal-036874	Ficedula albicollis	51.29	8.00e-154	538.00
IUUC-Gmo-039164	Gadus morhua	50.65	1.00e-172	600.00
IUUC-Gga-041092	Gallus gallus	52.32	0.00e+00	634.00
IUUC-Gac-042087	Gasterosteus aculeatus	49.58	0.00e+00	827.00
IUUC-Ggo-045171	Gorilla gorilla	78.68	0.00e+00	1519.00
IUUC-Hsa-045961	Homo sapiens	79.22	0.00e+00	1531.00
IUUC-Itr-048673	Ictidomys tridecemlineatus	70.45	5.00e-178	617.00
IUUC-Lch-050332	Latimeria chalumnae	48.35	6.00e-173	602.00
IUUC-Loc-052852	Lepisosteus oculatus	60.37	0.00e+00	877.00
IUUC-Mcc-055431	Macaca mulatta	78.80	0.00e+00	1529.00
IUUC-Meu-056822	Macropus eugenii	43.58	1.00e-117	418.00
IUUC-Mga-060115	Meleagris gallopavo	50.59	1.00e-153	537.00
IUUC-Mmr-061035	Microcebus murinus	78.63	0.00e+00	1470.00
IUUC-Mdo-062172	Monodelphis domestica	65.37	0.00e+00	938.00
IUUC-Mmu-063966	Mus musculus	75.69	0.00e+00	1451.00
IUUC-Mpu-066307	Mustela putorius furo	73.37	0.00e+00	1316.00
IUUC-Mlu-067870	Myotis lucifugus	50.68	1.00e-170	593.00
IUUC-Nle-070172	Nomascus leucogenys	78.69	0.00e+00	1531.00
IUUC-Opr-070499	Ochotona princeps	84.57	0.00e+00	1035.00
IUUC-Ont-071920	Oreochromis niloticus	60.42	0.00e+00	858.00
IUUC-Oan-073175	Ornithorhynchus anatinus	50.08	2.00e-151	530.00
IUUC-Ocu-074014	Oryctolagus cuniculus	78.65	0.00e+00	1095.00
IUUC-Ola-086360	Oryzias latipes	50.65	0.00e+00	872.00
IUUC-Oga-088202	Otolemur garnettii	75.63	0.00e+00	1454.00
IUUC-Oar-089819	Ovis aries	76.23	0.00e+00	1415.00
IUUC-Ptr-091076	Pan troglodytes	79.31	0.00e+00	1532.00
IUUC-Pan-092248	Papio anubis	78.22	0.00e+00	1509.00
IUUC-Psi-093881	Pelodiscus sinensis	50.25	2.00e-151	530.00
IUUC-Pfo-096534	Poecilia formosa	48.05	0.00e+00	789.00
IUUC-Pab-098453	Pongo abelii	76.59	0.00e+00	1467.00
IUUC-Pca-100290	Procavia capensis	70.84	0.00e+00	858.00
IUUC-Pva-102317	Pteropus vampyrus	70.39	0.00e+00	1318.00
IUUC-Rno-104948	Rattus norvegicus	73.82	0.00e+00	1290.00
IUUC-Sha-106558	Sarcophilus harrisii	57.23	0.00e+00	1105.00
IUUC-Sar-113105	Sorex araneus	60.43	0.00e+00	961.00
IUUC-Ssc-115312	Sus scrofa	76.97	0.00e+00	1482.00
IUUC-Tgu-116889	Taeniopygia guttata	50.93	5.00e-153	535.00
IUUC-Tru-117995	Takifugu rubripes	60.48	0.00e+00	847.00
IUUC-Tsy-119325	Tarsius syrichta	70.83	0.00e+00	688.00
IUUC-Tni-120517	Tetraodon nigroviridis	57.75	0.00e+00	805.00
IUUC-Tbe-127439	Tupaia belangeri	65.32	1.00e-119	424.00
IUUC-Ttr-128829	Tursiops truncatus	69.41	0.00e+00	1297.00
IUUC-Vpa-130306	Vicugna pacos	76.32	4.00e-167	582.00
IUUC-Xtr-132509	Xenopus tropicalis	52.17	0.00e+00	628.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence