iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118098

UUCD1 version

UUC-TaR-00944

Ensembl Protein ID

ENSTRUP00000043726.1

UniProt Accession

H2V3E4; H2V3E4_TAKRU

Protein Name

Uncharacterized protein

Gene Name

KLHL10 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000017069.1	ENSTRUT00000043872.1	ENSTRUP00000043726.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.30e-13	50.4	15	79
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-08	33.6	114	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +D i++vg  ef+ hki+L+ +S++F+alf++     + k+ +ei+d++p+v r ++ + Yt++++ 
   Q: 15   TDAIIKVGHAEFQIHKIILSKCSRYFQALFTTWSAP-D-KNVYEIRDLSPDVTRLIIFYAYTSTVPV 79
           699***************************775554.4.7**********************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           eNc+gi +f+d++ c++L ++a++fil +F
   Q: 114  ENCIGIWQFSDICYCSQLQEKAFEFILCNF 143
           9*************************9887 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSESLYSKSC DNSFTDAIIK VGHAEFQIHK IILSKCSRYF QALFTTWSAP DKNVYEIRDL 60
SPDVTRLIIF YAYTSTVPVT STNAMELLLA ADRYNVLGIV EVCCDFLMEM LSTENCIGIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTTGGTGG TAACACTAGT AGCGTGTACT TTGTTCACTA CTACAGAAAA CTGATGCTTT 60
TTAACATCCT TACAGAAACA AAGAAGCTGT GGTTCTCTCT AATTCAACAA CCTGCTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0009566--P:fertilization
GO:0008584--P:male gonad development
GO:0016567--P:protein ubiquitination
GO:0007286--P:spermatid development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001576	Ailuropoda melanoleuca	48.82	2.00e-161	561.00
IUUC-Apl-003525	Anas platyrhynchos	45.83	9.00e-152	530.00
IUUC-Aca-005295	Anolis carolinensis	49.15	5.00e-134	471.00
IUUC-Ate-010500	Aspergillus terreus	25.51	2.00e-21	97.10
IUUC-Ame-010953	Astyanax mexicanus	39.82	2.00e-124	439.00
IUUC-Bta-013447	Bos taurus	48.82	4.00e-161	561.00
IUUC-Cja-019472	Callithrix jacchus	46.48	1.00e-98	353.00
IUUC-Cfa-020332	Canis familiaris	49.00	1.00e-161	563.00
IUUC-Cpo-021949	Cavia porcellus	47.48	4.00e-161	561.00
IUUC-Csa-023573	Chlorocebus sabaeus	49.00	4.00e-161	561.00
IUUC-Cho-024451	Choloepus hoffmanni	48.26	2.00e-145	508.00
IUUC-Cin-025680	Ciona intestinalis	38.51	7.00e-120	424.00
IUUC-Csv-026085	Ciona savignyi	38.41	6.00e-116	411.00
IUUC-Dre-028188	Danio rerio	45.60	2.00e-141	496.00
IUUC-Dno-029608	Dasypus novemcinctus	48.82	5.00e-161	561.00
IUUC-Dor-030200	Dipodomys ordii	49.03	7.00e-153	533.00
IUUC-Dme-031964	Drosophila melanogaster	36.16	2.00e-105	376.00
IUUC-Ete-032475	Echinops telfairi	47.18	1.00e-153	536.00
IUUC-Eca-034237	Equus caballus	48.82	5.00e-161	561.00
IUUC-Fca-036271	Felis catus	48.63	6.00e-161	560.00
IUUC-Fal-037352	Ficedula albicollis	47.17	4.00e-151	528.00
IUUC-Gga-040205	Gallus gallus	47.25	4.00e-155	541.00
IUUC-Gac-042569	Gasterosteus aculeatus	48.91	5.00e-162	564.00
IUUC-Ggo-045241	Gorilla gorilla	48.82	1.00e-160	559.00
IUUC-Hsa-047022	Homo sapiens	49.00	4.00e-161	561.00
IUUC-Itr-048079	Ictidomys tridecemlineatus	48.82	4.00e-161	561.00
IUUC-Lch-050637	Latimeria chalumnae	49.00	5.00e-161	561.00
IUUC-Loc-052412	Lepisosteus oculatus	43.85	7.00e-139	487.00
IUUC-Laf-054118	Loxodonta africana	48.82	5.00e-161	561.00
IUUC-Mcc-055476	Macaca mulatta	43.90	1.00e-136	479.00
IUUC-Meu-056158	Macropus eugenii	48.82	4.00e-161	561.00
IUUC-Mga-059634	Meleagris gallopavo	47.07	2.00e-153	536.00
IUUC-Mmr-061217	Microcebus murinus	42.81	3.00e-131	462.00
IUUC-Mdo-062138	Monodelphis domestica	48.82	9.00e-161	560.00
IUUC-Mmu-063769	Mus musculus	48.82	4.00e-161	561.00
IUUC-Mpu-066045	Mustela putorius furo	48.82	5.00e-161	561.00
IUUC-Mlu-067348	Myotis lucifugus	48.82	3.00e-161	561.00
IUUC-Nle-069331	Nomascus leucogenys	49.36	2.00e-160	559.00
IUUC-Opr-071203	Ochotona princeps	46.99	2.00e-152	532.00
IUUC-Ont-071882	Oreochromis niloticus	40.07	3.00e-114	405.00
IUUC-Ocu-073757	Oryctolagus cuniculus	48.82	1.00e-160	559.00
IUUC-Ola-086791	Oryzias latipes	44.57	3.00e-135	475.00
IUUC-Oga-088676	Otolemur garnettii	49.18	1.00e-161	563.00
IUUC-Oar-089804	Ovis aries	48.82	1.00e-160	560.00
IUUC-Ptr-090767	Pan troglodytes	48.82	2.00e-160	558.00
IUUC-Pan-092856	Papio anubis	49.00	4.00e-161	561.00
IUUC-Psi-094041	Pelodiscus sinensis	48.45	1.00e-159	556.00
IUUC-Ppa-095209	Physcomitrella patens	30.26	1.00e-25	110.00
IUUC-Pfo-096673	Poecilia formosa	48.02	7.00e-157	547.00
IUUC-Pab-097694	Pongo abelii	48.82	7.00e-161	560.00
IUUC-Pca-100693	Procavia capensis	44.21	5.00e-126	444.00
IUUC-Pva-102153	Pteropus vampyrus	47.20	4.00e-108	385.00
IUUC-Rno-105012	Rattus norvegicus	48.82	5.00e-161	561.00
IUUC-Sha-106593	Sarcophilus harrisii	48.82	4.00e-161	561.00
IUUC-Sar-113188	Sorex araneus	48.27	3.00e-154	538.00
IUUC-Tgu-116852	Taeniopygia guttata	46.29	2.00e-146	512.00
IUUC-Tsy-119581	Tarsius syrichta	41.53	7.00e-125	441.00
IUUC-Tni-120002	Tetraodon nigroviridis	80.27	0.00e+00	879.00
IUUC-Tbe-127778	Tupaia belangeri	44.38	3.00e-138	485.00
IUUC-Ttr-128966	Tursiops truncatus	46.81	4.00e-148	518.00
IUUC-Vpa-130421	Vicugna pacos	46.48	5.00e-99	355.00
IUUC-Xtr-131853	Xenopus tropicalis	44.89	1.00e-137	483.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence